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A streamlined CRISPR-based test for tuberculosis detection directly from sputum

Authors: Alexandra G Bell, Owen R S Dunkley, Nisha H Modi, Yujia Huang, Soleil Tseng, Robert Reiss, Naranjargal Daivaa, J Lucian Davis, Deninson Alejandro Vargas, Padmapriya Banada, Yingda L Xie, Cameron Myhrvold

Journal: SCIENCE ADVANCES

PubMed ID: 40768573

Doi: 10.1126/sciadv.adx2067

Products & Services: Catalog Gene Editing

Guanidine aptamers are present in vertebrate RNAs associated with calcium signaling and neuromuscular function

Authors: Kumari Kavita, Aya Narunsky, Jessica J Mohsen, Isha Mahadeshwar, Michael G Mohsen, Yu-Shin Chang, Ronald R Breaker

Journal: Nature Communications

PubMed ID: 40783389

Doi: 10.1038/s41467-025-62815-6

Products & Services: Gene Synthesis

eIF2A regulates cell migration in a translation-independent manner

Authors: Jennifer Jungfleisch, Neus Mestre-Farràs, Raúl Gómez-Riera, Oriane Pourcelot, Edouard Bertrand, Nadia Halidi, Fátima Gebauer

Journal: SCIENCE ADVANCES

PubMed ID: 40749049

Doi: 10.1126/sciadv.adu5668

Dopamine signaling drives skin invasion by human-infective nematodes

Authors: Ruhi Patel, Gloria Bartolo, Michelle L Castelletto, Aracely Garcia Romero, Astra S Bryant, George W Agak, Elissa A Hallem

Journal: Nature Communications

PubMed ID: 40804046

Doi: 10.1038/s41467-025-62517-z.

Products & Services: Gene Synthesis

HERV-K TM Subunit Elicits CD8+ T Cell Anergy and Tumor Immune Evasion via Targeting CD3 Coreceptor ε in AML and PDAC

Authors: Mengyuan Li, Shuwen Zheng, Qinyuan Gong, Zhaoxing Wu, Wen Lei, Wanyue Cao, Ping Wang, Xuzhao Zhang, Wenbin Qian, Yun Liang, Ying Lu, Fenglin Li, Qi Zhang, Rongzhen Xu

Journal: Advanced Science

PubMed ID: 40801282

Doi: 10.1002/advs.202417432

Products & Services: Cell Isolation

4D structural biology-quantitative dynamics in the eukaryotic RNA exosome complex

Authors: Jobst Liebau, Daniela Lazzaretti, Torben Fürtges, Anna Bichler, Michael Pilsl, Till Rudack, Remco Sprangers

Journal: Nature Communications

PubMed ID: 40849410

Doi: 10.1038/s41467-025-62982-6.

Products & Services: Codon Optimization

Epsin1 enforces a condensation-dependent checkpoint for ubiquitylated cargo during clathrin-mediated endocytosis

Authors: Susovan Sarkar, Hao-Yang Liu, Feng Yuan, Brandon T Malady, Liping Wang, Eileen M Lafer, Jessica Perez, Jon M Huibregtse, Jeanne C Stachowiak

Journal: Nature Communications

PubMed ID: 40854908

Doi: 10.1038/s41467-025-63238-z.

Products & Services: Custom Vector Construction

Viral proteins suppress rice defenses by boosting OsTSN1 RNA decay via phase separation and multimerization

Authors: Ming Zeng, Shuai Fu, Youping Xu, Liyan Li, Dan Wang, Shi-Bo Gao, Lianshun Zheng, Yunge Zhang, Cui Zhang, Shifang Fei, Xuan Ye, Lele Chen, Yaqin Wang, Tong Zhang, Xueping Zhou, Jianxiang Wu

Journal: Nature Communications

PubMed ID: 40796552

Doi: 10.1038/s41467-025-62395-5.

Products & Services: Protein and Antibody Isolation

Control of Golgi- V-ATPase through Sac1-dependent co-regulation of PI(4)P and cholesterol

Authors: Xin Zhou, Miesje M van der Stoel, Shreyas Kaptan, Haoran Li, Shiqian Li, Maarit Hölttä, Helena Vihinen, Eija Jokitalo, Christoph Thiele, Olli Pietiläinen, Shin Morioka, Junko Sasaki, Takehiko Sasaki, Ilpo Vattulainen, Elina Ikonen

Journal: Nature Communications

PubMed ID: 40841558

Doi: 10.1038/s41467-025-63125-7.

Products & Services: Polyclonal Antibody Services

Noncanonical roles of chemokine regions in CCR9 activation revealed by structural modeling and mutational mapping

Authors: Inês De Magalhaes Pinheiro, John R D Dawson, Nicolas Calo, Marianne Paolini-Bertrand, Kalyana Bharati Akondi, Gavin Tan, Tracy M Handel, Irina Kufareva, Oliver Hartley

Journal: Nature Communications

PubMed ID: 40825773

Doi: 10.1038/s41467-025-62321-9.

Products & Services: Mutagenesis Services