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Structural basis for double-stranded RNA recognition by SID1

Authors: Runhao Wang, Ye Cong, Dandan Qian, Chuangye Yan, Deshun Gong

Journal: Nucleic Acids Res

PubMed ID: 38742627

Doi: 10.1093/nar/gkae395

Enhanced detection of ligand-PPARγ binding based on surface plasmon resonance through complexation with SRC1- or NCOR2-related polypeptide

Authors: Yiting Wang , Mingzhu Luo , Luyang Che , Qixin Wu , Jingzhe Li , Yanyan Ma , Jingyi Wang , Changzhen Liu

Journal: International Journal of Biological Macromolecules

PubMed ID: 38670200

Doi: 10.1016/j.ijbiomac.2024.131865

Products & Services: Gene Synthesis

A Tag-Free Platform for Synthesis and Screening of Cyclic Peptide Libraries

Authors: Angele Bruce , Victor Adebomi , Patrick Czabala , Jonathan Palmer , William M McFadden , Zachary C Lorson , Ryan L Slack , Gaurav Bhardwaj , Stefan G Sarafianos , Monika Raj

Journal: Angew Chem Int Ed Engl

PubMed ID: 38529717

Doi: 10.1002/anie.202320045

Products & Services: PCR Cloning and Subcloning

Gene network-based and ensemble modeling-based selection of tumor-associated antigens with a predicted low risk of tissue damage for targeted immunotherapy

Authors: Christopher Lischer, Martin Eberhardt, Cindy Flamann, Johannes Berges, Esther Güse, Anja Wessely, Adrian Weich, Jimmy Retzlaff, Jan Dörrie, Niels Schaft, Manuel Wiesinger, Johannes März, Beatrice Schuler-Thurner, Harald Knorr, Shailendra Gupta, Krishna Pal Singh, Gerold Schuler, Markus Vincent Heppt, Elias Andreas Thomas Koch, Nadine D van Kleef, Julian J Freen-van Heeren, Annelies W Turksma, Olaf Wolkenhauer, Bettina Hohberger, Carola Berking, Heiko Bruns, Julio Vera

Journal: J Immunother Cancer

PubMed ID: 38724462

Doi: 10.1136/jitc-2023-008104

Products & Services: Gene Synthesis

CircZFR promotes colorectal cancer progression via stabilizing BCLAF1 and regulating the miR-3127-5p/RTKN2 axis

Authors: Jiaxin Chen, Huijuan Wang, Jianbin Xu, Engeng Chen, Qing Meng, Jiawei Wang, Haoyi Xiang, Wei Zhou, Ge Shan, Zhenyu Ju, Zhangfa Song

Journal: Sci China Life Sci

PubMed ID: 38805063

Doi: 10.1007/s11427-023-2514-y

Products & Services: Protein and Antibody Isolation

Structure-Based Virtual Screening for Methyltransferase Inhibitors of SARS-CoV-2 nsp14 and nsp16

Authors: Kejue Wu, Yinfeng Guo, Tiefeng Xu, Weifeng Huang, Deyin Guo, Liu Cao, Jinping Lei

Journal: Molecules

PubMed ID: 38792173

Doi: 10.3390/molecules29102312

Products & Services: Molecular Biology Reagents

Design, synthesis and evaluation of thieno[3,2-d]pyrimidine derivatives as novel potent CDK7 inhibitors

Authors: Hongjin Zhang, Guohao Lin, Suyun Jia, Jianbo Wu, Ying Zhang, Yanxin Tao, Weixue Huang, Meiru Song, Ke Ding, Dawei Ma, Mengyang Fan

Journal: Bioorg Chem

PubMed ID: 38761706

Doi: 10.1016/j.bioorg.2024.107456

Products & Services: Recombinant Proteins

Kanglexin counters vascular smooth muscle cell dedifferentiation and associated arteriosclerosis through inhibiting PDGFR

Authors: Shuang Yang, Yixiu Zhao, Shifeng Cao, Xinxin Liu, Min Feng, Yi Chen, Chunyue Ma, Tingting Zhan, Qi Zhang, Honglin Jia, Yu Zhao, Ming Tong, Yuanyuan Yu, Xue Liu, Baofeng Yang, Yan Zhang

Journal: Phytomedicine

PubMed ID: 38759316

Doi: 10.1016/j.phymed.2024.155704

Products & Services: Molecular Biology Reagents

TOP CAR with TMIGD2 as a safe and effective costimulatory domain in CAR cells treating human solid tumors

Authors: Christopher D Nishimura, Devin Corrigan, Xiang Yu Zheng, Phillip M Galbo, Shan Wang, Yao Liu, Yao Wei, Linna Suo, Wei Cui, Nadia Mercado, Deyou Zheng, Cheng Cheng Zhang, Xingxing Zang

Journal: Sci Adv

PubMed ID: 38718110

Doi: 10.1126/sciadv.adk1857

Products & Services: Protein and Antibody Isolation

Glycan Profile and Sequence Variants of Certified Ricin Reference Material and Other Ricin Samples Yield Unique Molecular Signature Features

Authors: Roland Josuran, Andreas Wenger, Christian Müller, Bettina Kampa, Sylvia Worbs, Brigitte G Dorner, Sabina Gerber

Journal: Toxins (Basel)

PubMed ID: 38922138

Doi: 10.3390/toxins16060243

Products & Services: Protein and Antibody Isolation