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A systematic analysis of affinity tags in the haloarchaeal expression system, for protein purification
Authors: Ram Karan, Dominik Renn, Thorsten Allers, Magnus Rueping
Journal: Front Microbiol
PubMed ID: 38873150
Doi: 10.3389/fmicb.2024.1403623
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CRISPR-Cas9 immune-evasive hESCs are rejected following transplantation into immunocompetent mice
Authors: Henriette Reventlow Frederiksen, Alexandra Glantz, Kåre Kryger Vøls, Søren Skov, Pernille Tveden-Nyborg, Kristine Freude, Ulrik Doehn
Journal: Front Genome Ed
PubMed ID: 38863835
Doi: 10.3389/fgeed.2024.1403395
Products & Services: Molecular Biology Reagents   
Understanding the Enzyme ()-Norcoclaurine Synthase Promiscuity to Aldehydes and Ketones
Authors: Brunno A Salvatti, Marcelo A Chagas, Phillipe O Fernandes, Yan F X Ladeira, Aline S Bozzi, Veronica S Valadares, Ana Paula Valente, Amanda S de Miranda, Willian R Rocha, Vinicius G Maltarollo, Adolfo H Moraes
Journal: J Chem Inf Model
PubMed ID: 38776464
Doi: 10.1021/acs.jcim.3c01773
Products & Services: Molecular Biology Reagents   
Therapeutic potentials of nonpeptidic V2R agonists for partial cNDI-causing V2R mutants
Authors: Ritsuki Kuramoto, Ryoji Kise, Mayu Kanno, Kouki Kawakami, Tatsuya Ikuta, Noriko Makita, Asuka Inoue
Journal: PLoS ONE
PubMed ID: 38748623
Doi: 10.1371/journal.pone.0303507
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HIV BG505 SOSIP664 trimer with 3M-052-AF/alum induces human autologous tier-2 neutralizing antibodies
Authors: William O Hahn, K Rachael Parks, Mingchao Shen, Gabriel Ozorowski, Holly Janes, Lamar Ballweber-Fleming, Amanda S Woodward Davis, Chris Duplessis, Mark Tomai, Antu K Dey, Zachary K Sagawa, Stephen C De Rosa, Aaron Seese, Latha Kallur Siddaramaiah, Leonidas Stamatatos, Wen-Hsin Lee, Leigh M Sewall, Dalton Karlinsey, Hannah L Turner, Vanessa Rubin, Sarah Furth, Kellie MacPhee, Michael Duff, Lawrence Corey, Michael C Keefer, Srilatha Edupuganti, Ian Frank, Janine Maenza, Lindsey R Baden, Ollivier Hyrien, Rogier W Sanders, John P Moore, Andrew B Ward, Georgia D Tomaras, David C Montefiori, Nadine Rouphael, M Juliana McElrath
Journal: medrxiv
PubMed ID: 38766048
Doi: 10.1101/2024.05.08.24306957
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A Novel Fluorescence-Based Microplate Assay for High-Throughput Screening of hSULT1As Inhibitors
Authors: Xiaoting Niu, Yufan Fan, Liwei Zou, Guangbo Ge
Journal: Biosensors (Basel)
PubMed ID: 38920579
Doi: 10.3390/bios14060275
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Anticancer Effects of the Trivalent Organoarsenical 2-Amino-4-(dihydroxyarsinoyl) Butanoate
Authors: Venkadesh Sarkarai Nadar, Kunie Yoshinaga-Sakurai, Barry P Rosen
Journal: Organometallics
PubMed ID: 38817537
Doi: 10.1021/acs.organomet.4c00082
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The intrinsic substrate specificity of the human tyrosine kinome
Authors: Tomer M. Yaron-Barir, Brian A. Joughin, Emily M. Huntsman, Alexander Kerelsky, Daniel M. Cizin, Benjamin M. Cohen, Amit Regev, Junho Song, Neil Vasan, Ting-Yu Lin, Jose M. Orozco, Christina Schoenherr, Cari Sagum, Mark T. Bedford, R. Max Wynn, Shih-Chia Tso, David T. Chuang, Lei Li, Shawn S.-C. Li, Pau Creixell, Konstantin Krismer, Mina Takegami, Harin Lee, Bin Zhang, Jingyi Lu, Ian Cossentino, Sean D. Landry, Mohamed Uduman, John Blenis, Olivier Elemento, Margaret C. Frame, Peter V. Hornbeck, Lewis C. Cantley, Benjamin E. Turk, Michael B. Yaffe & Jared L. Johnson
Journal: Nature
PubMed ID: 38720073
Doi: 10.1038/s41586-024-07407-y
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Mycobacterial biotin synthases require an auxiliary protein to convert dethiobiotin into biotin
Authors: Di Qu, Peng Ge, Laure Botella, Sae Woong Park, Ha-Na Lee, Natalie Thornton, James M. Bean, Inna V. Krieger, James C. Sacchettini, Sabine Ehrt, Courtney C. Aldrich & Dirk Schnappinger
Journal: Nat Commun
PubMed ID: 38755122
Doi: 10.1038/s41467-024-48448-1.
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Contemporary HIV-1 consensus Env with AI-assisted redesigned hypervariable loops promote antibody binding
Authors: Hongjun Bai, Eric Lewitus, Yifan Li, Paul V. Thomas, Michelle Zemil, Mélanie Merbah, Caroline E. Peterson, Thujitha Thuraisamy, Phyllis A. Rees, Agnes Hajduczki, Vincent Dussupt, Bonnie Slike, Letzibeth Mendez-Rivera, Annika Schmid, Erin Kavusak, Mekhala Rao, Gabriel Smith, Jessica Frey, Alicea Sims, Lindsay Wieczorek, Victoria Polonis, Shelly J. Krebs, Julie A. Ake, Sandhya Vasan, Diane L. Bolton, M. Gordon Joyce, Samantha Townsley & Morgane Rolland
Journal: Nat Commun
PubMed ID: 38724518
Doi: 10.1038/s41467-024-48139-x
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