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Insights into PCSK9-LDLR Regulation and Trafficking via the Differential Functions of MHC-I Proteins HFE and HLA-C

Authors: Sepideh Mikaeeli, Ali Ben Djoudi Ouadda, Alexandra Evagelidis, Rachid Essalmani, Oscar Henrique Pereira Ramos, Carole Fruchart-Gaillard, Nabil G Seidah

Journal: Cells

PubMed ID: 38786080

Doi: 10.3390/cells13100857

Products & Services: Mutant Libraries

L-serine deficiency: on the properties of the Asn133Ser variant of human phosphoserine phosphatase

Authors: Loredano Pollegioni, Barbara Campanini, Jean-Marc Good, Zoraide Motta, Giulia Murtas, Valeria Buoli Comani, Despina-Christina Pavlidou, Noëlle Mercier, Laureane Mittaz-Crettol, Silvia Sacchi, Francesco Marchesani

Journal: Sci Rep

PubMed ID: 38816452

Doi: 10.1038/s41598-024-63164-y

Products & Services: Protein and Antibody Isolation

The interaction of GRP78 and Zika virus E and NS1 proteins occurs in a chaperone-client manner

Authors: Wannapa Sornjai, Ploenphit Promma, Suphansa Priewkhiew, Suwipa Ramphan, Janejira Jaratsittisin, Pailin Jinagool, Nitwara Wikan, Michael Greenwood, David Murphy, Duncan R Smith

Journal: Sci Rep

PubMed ID: 38710792

Doi: 10.1038/s41598-024-61195-z

Products & Services: Molecular Biology Reagents

Gene network-based and ensemble modeling-based selection of tumor-associated antigens with a predicted low risk of tissue damage for targeted immunotherapy

Authors: Christopher Lischer, Martin Eberhardt, Cindy Flamann, Johannes Berges, Esther Güse, Anja Wessely, Adrian Weich, Jimmy Retzlaff, Jan Dörrie, Niels Schaft, Manuel Wiesinger, Johannes März, Beatrice Schuler-Thurner, Harald Knorr, Shailendra Gupta, Krishna Pal Singh, Gerold Schuler, Markus Vincent Heppt, Elias Andreas Thomas Koch, Nadine D van Kleef, Julian J Freen-van Heeren, Annelies W Turksma, Olaf Wolkenhauer, Bettina Hohberger, Carola Berking, Heiko Bruns, Julio Vera

Journal: J Immunother Cancer

PubMed ID: 38724462

Doi: 10.1136/jitc-2023-008104

Products & Services: Gene Synthesis

CircZFR promotes colorectal cancer progression via stabilizing BCLAF1 and regulating the miR-3127-5p/RTKN2 axis

Authors: Jiaxin Chen, Huijuan Wang, Jianbin Xu, Engeng Chen, Qing Meng, Jiawei Wang, Haoyi Xiang, Wei Zhou, Ge Shan, Zhenyu Ju, Zhangfa Song

Journal: Sci China Life Sci

PubMed ID: 38805063

Doi: 10.1007/s11427-023-2514-y

Products & Services: Protein and Antibody Isolation

Structure-Based Virtual Screening for Methyltransferase Inhibitors of SARS-CoV-2 nsp14 and nsp16

Authors: Kejue Wu, Yinfeng Guo, Tiefeng Xu, Weifeng Huang, Deyin Guo, Liu Cao, Jinping Lei