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IgE-activated mast cells enhance TLR4-mediated antigen-specific CD4 T cell responses
Authors: Binh L Phong, Shaina J D'Souza, Robin L Baudier, Eric Wu, Victoria E Immethun, David L Bauer, James B McLachlan
Journal: Sci Rep
PubMed ID: 33958642
Doi: 10.1038/s41598-021-88956-4
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Minimally invasive brain injections for viral-mediated transgenesis: New tools for behavioral genetics in sticklebacks
Authors: Noelle James, Alison Bell
Journal: PLoS ONE
PubMed ID: 33999965
Doi: 10.1371/journal.pone.0251653
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S-acylation of P2K1 mediates extracellular ATP-induced immune signaling in Arabidopsis
Authors: Dongqin Chen, Fengsheng Hao, Huiqi Mu, Nagib Ahsan, Jay J Thelen, Gary Stacey
Journal: Nat Commun
PubMed ID: 33980819
Doi: 10.1038/s41467-021-22854-1
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Qki activates Srebp2-mediated cholesterol biosynthesis for maintenance of eye lens transparency
Authors: Seula Shin, Hao Zhou, Chenxi He, Yanjun Wei, Yunfei Wang, Takashi Shingu, Ailiang Zeng, Shaobo Wang, Xin Zhou, Hongtao Li, Qiang Zhang, Qinling Mo, Jiafu Long, Fei Lan, Yiwen Chen, Jian Hu
Journal: Nat Commun
PubMed ID: 34021134
Doi: 10.1038/s41467-021-22782-0
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Lipid-nanoparticle-encapsulated mRNA vaccines induce protective memory CD8 T cells against a lethal viral infection
Authors: Cory J Knudson, Pedro Alves-Peixoto, Hiromi Muramatsu, Colby Stotesbury, Lingjuan Tang, Paulo J C Lin, Ying K Tam, Drew Weissman, Norbert Pardi, Luis J Sigal
Journal: Mol Ther
PubMed ID: 33992803
Doi: 10.1016/j.ymthe.2021.05.011
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Qki regulates myelinogenesis through Srebp2-dependent cholesterol biosynthesis
Authors: Xin Zhou, Seula Shin, Chenxi He, Qiang Zhang, Matthew N Rasband, Jiangong Ren, Congxin Dai, Rocío I Zorrilla-Veloz, Takashi Shingu, Liang Yuan, Yunfei Wang, Yiwen Chen, Fei Lan, Jian Hu
Journal: Elife
PubMed ID: 33942715
Doi: 10.7554/eLife.60467
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The human tRNA-guanine transglycosylase displays promiscuous nucleobase preference but strict tRNA specificity
Authors: Claire Fergus, Mashael Al-Qasem, Michelle Cotter, Ciara M McDonnell, Emiliano Sorrentino, Franciane Chevot, Karsten Hokamp, Mathias O Senge, John M Southern, Stephen J Connon, Vincent P Kelly
Journal: Nucleic Acids Res
PubMed ID: 34009357
Doi: 10.1093/nar/gkab289
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PD-L2 suppresses T cell signaling via coinhibitory microcluster formation and SHP2 phosphatase recruitment
Authors: Tomohiro Takehara, Ei Wakamatsu, Hiroaki Machiyama, Wataru Nishi, Katsura Emoto, Miyuki Azuma, Kenzo Soejima, Koichi Fukunaga, Tadashi Yokosuka
Journal: Commun Biol
PubMed ID: 33990697
Doi: 10.1038/s42003-021-02111-3
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A participant-derived xenograft model of HIV enables long-term evaluation of autologous immunotherapies
Authors: Chase D McCann, Christiaan H van Dorp, Ali Danesh, Adam R Ward, Thomas R Dilling, Talia M Mota, Elizabeth Zale, Eva M Stevenson, Shabnum Patel, Chanson J Brumme, Winnie Dong, Douglas S Jones, Thomas L Andresen, Bruce D Walker, Zabrina L Brumme, Catherine M Bollard, Alan S Perelson, Darrell J Irvine, R Brad Jones
Journal: J Exp Med
PubMed ID: 33988715
Doi: 10.1084/jem.20201908
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Calmodulin complexes with brain and muscle creatine kinase peptides
Authors: Janina Sprenger, Anda Trifan, Neal Patel, Ashley Vanderbeck, Jenny Bredfelt, Emad Tajkhorshid, Roger Rowlett, Leila Lo Leggio, Karin S Åkerfeldt, Sara Linse
Journal: Curr Res Struct Biol
PubMed ID: 34235492
Doi: 10.1016/j.crstbi.2021.05.001
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