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CD112 Lactylation Drives Dual Immune Evasion From CD8+ T Cells and NK Cells

Authors: Zhuoshuo Xu, Xinyu Zhang, Fang Dong, Nenghao Shen, Jun Zhou, Zihan Xi, Zhenghao Wu

Journal: Advanced Science

PubMed ID: 42829916

Doi: 10.1002/advs.78088

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Sensory neuron-derived CGRP ameliorates kidney injury and fibrosis via monocytes and macrophages

Authors: Lei Wang, Huaikang Li, Ji Feng, Jianwen Chen, Tongyu Jia, Tailai Zhou, Li Wang, Lu Tang, Xu Zhang, Xin Ma

Journal: Cell Research

PubMed ID: 42918818

Doi: 10.1038/s41422-026-01308-7

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Cofilin1-driven cytoskeletal remodeling modulates pan-cancer CD8 T cell immunotherapy responses

Authors: Le Li, Zheng Chao, Junbo Li, Chao Ma, Ren Zhang, Jie Zhang, Jing Luo, David Horne, Yanan Wang, Xiaodong Hao, Chunyu Zhang, Xiangdong Guo, Sheng Ma, Hao Peng, Zhiquan Hu, Bertram Yuh, Gong-Hong Wei, Xiangping Yang, Qiang Zhang, Baojun Wang, Xu Zhang, Zheng Liu, Zhihong Zhang, Peixiang Lan, Zhihua Wang

Journal: Cell Reports Medicine

PubMed ID: 42586064

Doi: 10.1016/j.xcrm.2026.102984

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Surface immune signaling unlocks NLR activation through mRNA alternative splicing

Authors: Chuyun Gao, Xi Meng, Xianchu Chen, Leiyun Yang, Tarhan Ibrahim, AmirAli Toghani, Enoch Lok Him Yuen, Nick Eilmann, Freddie King, Kangping Li, Luyao Wang, Biying Sun, Yuanchao Wang, Tolga Osman Bozkurt, Suomeng Dong

Journal: Science

PubMed ID: 42391383

Doi: 10.1126/science.adx9929

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DGAT1 Inhibition Induces Ferroptosis and Enhances Cancer Immunotherapy Efficacy

Authors: Dong Pan, Meng Jiao, Yanyan Zhu, Mengjie Hu, Fang Li, Jinming Yu, Chuan-Yuan Li

Journal: Cancer Research

PubMed ID: 41812065

Doi: 10.1158/0008-5472.CAN-25-0840

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Substituent-Based Modulation of Self-Assembly and Immunogenicity of Amphipathic Peptides

Authors: Anirban Das, Ushasi Pramanik, Elise M Brown, Chih-Yun Liu, Huan Gong, Jonathan Fascetti, Mark Gibson, Samuel Stealey, Silviya P Zustiak, Cory Berkland, Piyoosh Sharma, Meredith E Jackrel, Mark A White, Jai S Rudra

Journal: Advanced Science

PubMed ID: 41560329

Doi: 10.1002/advs.202518567

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A dsRNA Viral Transcriptional Regulator Evades Innate Immunity by Hijacking Host CoTranscription Factor DHX9

Authors: Xueyang Pang, Shiyu Liu, Yixiao Zhu, Meleana M Hinchman, Nan Qiao, Xuejun Li, Weiqian Dai, Yingying Tong, Man Xing, Jiling Ren, John S L Parker, Yingying Guo, Dongming Zhou

Journal: Advanced Science

PubMed ID: 41431149

Doi: 10.1002/advs.202512262

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Structural snapshots capture nucleotide release at the μ-opioid receptor

Authors: Saif Khan, Aaliyah S Tyson, Mohsen Ranjbar, Zixin Zhang, Jaskaran Singh, Gye Won Han, Cornelius Gati

Journal: Nature

PubMed ID: 41193810

Doi: 10.1038/s41586-025-09677-6.

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A ternary switch model governing ERα ligand binding domain conformation

Authors: Daniel P McDougal, Jordan L Pederick, Scott J Novick, Blagojce Jovcevski, Annmaree K Warrender, Bruce D Pascal, Patrick R Griffin, John B Bruning

Journal: Nature Communications

PubMed ID: 41285747

Doi: 10.1038/s41467-025-65323-9.

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A de novo missense variant in MIDEAS results in increased deacetylase activity of the MiDAC HDAC complex causing a neurodevelopmental syndrome

Authors: Louise Fairall, Kristupas Sirvydis, Robert E Turnbull, Suzan Jg Knottnerus, Oksana Gonchar, Frederick W Muskett, Rebekah Jukes-Jones, Lonneke van Brussel, Ellen van de Geer, Koen van Gassen, Paul Badenhorst, Diana Johnson, Paulien A Terhal, Peter M van Hasselt, Richard H van Jaarsveld, John Wr Schwabe

Journal: Nature Communications

PubMed ID: 41290615

Doi: 10.1038/s41467-025-65472-x.

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