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Targeted Radionuclide Therapy Using Auger Electron Emitters: The Quest for the Right Vector and the Right Radionuclide
Authors: Malick Bio Idrissou, Alexandre Pichard, Bryan Tee, Tibor Kibedi, Sophie Poty, Jean-Pierre Pouget
Journal: Pharmaceutics
PubMed ID: 34209637
Doi: 10.3390/pharmaceutics13070980
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Atherosclerosis-associated hepatic secretion of VLDL but not PCSK9 is dependent on cargo receptor protein Surf4
Authors: Bingxiang Wang, Yishi Shen, Lei Zhai, Xiaodan Xia, Hong-Mei Gu, Maggie Wang, Yongfang Zhao, Xiaole Chang, Adekunle Alabi, Sijie Xing, Shijun Deng, Boyan Liu, Guiqing Wang, Shucun Qin, Da-Wei Zhang
Journal: J Lipid Res
PubMed ID: 34118252
Doi: 10.1016/j.jlr.2021.100091
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Order and disorder-An integrative structure of the full-length human growth hormone receptor
Authors: Noah Kassem, Raul Araya-Secchi, Katrine Bugge, Abigail Barclay, Helena Steinocher, Adree Khondker, Yong Wang, Aneta J Lenard, Jochen Bürck, Cagla Sahin, Anne S Ulrich, Michael Landreh, Martin Cramer Pedersen, Maikel C Rheinstädter, Per Amstrup Pedersen, Kresten Lindorff-Larsen, Lise Arleth, Birthe B Kragelund
Journal: Sci Adv
PubMed ID: 34193419
Doi: 10.1126/sciadv.abh3805
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A newly identified linear epitope on non-RBD region of SARS-CoV-2 spike protein improves the serological detection rate of COVID-19 patients
Authors: Yunwen Zhang, Zhengrong Yang, Sicheng Tian, Baisheng Li, Tiejian Feng, Jianfan He, Min Jiang, Xiujuan Tang, Shujiang Mei, Hao Li, Yifan Zhong, Guilian Li, Mingyuan Tang, Sijing Liu, Tian Tang, Chuan Wang, Xiaohui Wang
Journal: BMC Microbiol
PubMed ID: 34174835
Doi: 10.1186/s12866-021-02241-y
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MiR-379-5p aggravates experimental autoimmune uveitis in mice via the regulation of SEMA3A
Authors: Mohan Li, Xiang Gao, Kou Liu, Ning Bao, Zhengxuan Jiang
Journal: Autoimmunity
PubMed ID: 34060391
Doi: 10.1080/08916934.2021.1931841
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Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation
Authors: Sushila A Toulmin, Chaitali Bhadiadra, Andrew J Paris, Jeffrey H Lin, Jeremy Katzen, Maria C Basil, Edward E Morrisey, G Scott Worthen, Laurence C Eisenlohr
Journal: Nat Commun
PubMed ID: 34183650
Doi: 10.1038/s41467-021-23619-6
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Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs
Authors: Shira Weingarten-Gabbay, Susan Klaeger, Siranush Sarkizova, Leah R Pearlman, Da-Yuan Chen, Kathleen M E Gallagher, Matthew R Bauer, Hannah B Taylor, W Augustine Dunn, Christina Tarr, John Sidney, Suzanna Rachimi, Hasahn L Conway, Katelin Katsis, Yuntong Wang, Del Leistritz-Edwards, Melissa R Durkin, Christopher H Tomkins-Tinch, Yaara Finkel, Aharon Nachshon, Matteo Gentili, Keith D Rivera, Isabel P Carulli, Vipheaviny A Chea, Abishek Chandrashekar, Cansu Cimen Bozkus, Mary Carrington, Nina Bhardwaj, Dan H Barouch, Alessandro Sette, Marcela V Maus, Charles M Rice, Karl R Clauser, Derin B Keskin, Daniel C Pregibon, Nir Hacohen, Steven A Carr, Jennifer G Abelin, Mohsan Saeed, Pardis C Sabeti
Journal: Cell
PubMed ID: 34171305
Doi: 10.1016/j.cell.2021.05.046
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Crizotinib acts as ABL1 inhibitor combining ATP-binding with allosteric inhibition and is active against native BCR-ABL1 and its resistance and compound mutants BCR-ABL1 and BCR-ABL1
Authors: Afsar Ali Mian, Isabella Haberbosch, Hazem Khamaisie, Abed Agbarya, Larissa Pietsch, Elizabeh Eshel, Dally Najib, Claudia Chiriches, Oliver Gerhard Ottmann, Oliver Hantschel, Ricardo M Biondi, Martin Ruthardt, Jamal Mahajna
Journal: Ann Hematol
PubMed ID: 34110462
Doi: 10.1007/s00277-020-04357-z
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Therapeutic Potential of HLA-I Polyreactive mAbs Mimicking the HLA-I Polyreactivity and Immunoregulatory Functions of IVIg
Authors: Mepur H Ravindranath, Fatiha El Hilali, Edward J Filippone
Journal: Vaccines (Basel)
PubMed ID: 34205517
Doi: 10.3390/vaccines9060680
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A vaccine inducing solely cytotoxic T lymphocytes fully prevents Zika virus infection and fetal damage
Authors: Frank Gambino, Wanbo Tai, Denis Voronin, Yi Zhang, Xiujuan Zhang, Juan Shi, Xinyi Wang, Ning Wang, Lanying Du, Liang Qiao
Journal: Cell Rep
PubMed ID: 33979612
Doi: 10.1016/j.celrep.2021.109107
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