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Structural basis of tetanus toxin neutralization by native human monoclonal antibodies

Authors: Yueming Wang, Changwen Wu, Jinfang Yu, Shujian Lin, Tong Liu, Lipeng Zan, Nan Li, Po Hong, Xiaoli Wang, Zhenxing Jia, Jason Li, Yao Wang, Ming Zhang, Xiaohui Yuan, Chengming Li, Wenwen Xu, Weihong Zheng, Xinquan Wang, Hua-Xin Liao

Journal: Cell Rep

PubMed ID: 33951441

Doi: 10.1016/j.celrep.2021.109070

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ADAM9 enhances Th17 cell differentiation and autoimmunity by activating TGF-β1

Authors: Masataka Umeda, Nobuya Yoshida, Ryo Hisada, Catalina Burbano, Seo Yeon K Orite, Michihito Kono, Vasileios C Kyttaris, Suzanne Krishfield, Caroline A Owen, George C Tsokos

Journal: Proc Natl Acad Sci U S A

PubMed ID: 33911034

Doi: 10.1073/pnas.2023230118

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Enhanced dengue vaccine virus replication and neutralizing antibody responses in immune primed rhesus macaques

Authors: Michael K McCracken, Caitlin H Kuklis, Chandrika B Kannadka, David A Barvir, Mark A Sanborn, Adam T Waickman, Hayden C Siegfried, Kaitlin A Victor, Kristin L Hatch, Rafael De La Barrera, Shannon D Walls, Wiriya Rutvisuttinunt, Jeffrey R Currier, Heather Friberg, Richard G Jarman, Gregory D Gromowski

Journal: npj Vaccines

PubMed ID: 34021159

Doi: 10.1038/s41541-021-00339-y

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Circular RNA ITCH promotes extracellular matrix degradation via activating Wnt/β-catenin signaling in intervertebral disc degeneration

Authors: Feng Zhang, Feili Lin, Zhiwen Xu, Zheng Huang

Journal: Aging (Albany NY)

PubMed ID: 34015763

Doi: 10.18632/aging.203036

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Dopaminergic signalling limits suppressive activity and gut homing of regulatory T cells upon intestinal inflammation

Authors: Ugalde V, Contreras F, Prado C, Chovar O, Espinoza A, Pacheco R

Journal: Mucosal Immunology

PubMed ID: 33184477

Doi: 10.1038/s41385-020-00354-7

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Extracellular vesicles-encapsulated microRNA-10a-5p shed from cancer-associated fibroblast facilitates cervical squamous cell carcinoma cell angiogenesis and tumorigenicity via Hedgehog signaling pathway

Authors: Zhang X, Wang Y, Wang X, Zou B, Mei J, Peng X, Wu Z

Journal: Cancer gene therapy

PubMed ID: 33235271

Doi: 10.1038/s41417-020-00238-9

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Structural characterization of NORAD reveals a stabilizing role of spacers and two new repeat units

Authors: Uciel Chorostecki, Ester Saus, Toni Gabaldón

Journal: Comput Struct Biotechnol J

PubMed ID: 34141143

Doi: 10.1016/j.csbj.2021.05.045

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Lovastatin attenuates sevoflurane-induced cognitive disorder in aged rats via reducing Aβ accumulation

Authors: Ying Xu, Yunxia Dong, Cong Wang, Qian Jiang, Haichao Chu, Yue Tian

Journal: Neurochem Int

PubMed ID: 34048842

Doi: 10.1016/j.neuint.2021.105078

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CNP regulates cardiac contractility and increases cGMP near both SERCA and TnI - difference from BNP visualized by targeted cGMP biosensors

Authors: Ornella Manfra, Gaia Calamera, Alexander Froese, Dulasi Arunthavarajah, Nicoletta C Surdo, Silja Meier, Arne Olav Melleby, Monica Aasrum, Jan Magnus Aronsen, Viacheslav O Nikolaev, Manuela Zaccolo, Lise Román Moltzau, Finn Olav Levy, Kjetil Wessel Andressen

Journal: Cardiovasc Res

PubMed ID: 33970224

Doi: 10.1093/cvr/cvab167

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Subthreshold Nanosecond Laser, from Trials to Real-Life Clinical Practice: A Cohort Study

Authors: Hasan Chichan, Matthias Maus, Ludwig M Heindl

Journal: Clin Ophthalmol

PubMed ID: 33986589

Doi: 10.2147/OPTH.S307671

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