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Aldo-Keto Reductase 1C3 Mediates Chemotherapy Resistance in Esophageal Adenocarcinoma via ROS Detoxification

Authors: Chenghui Zhou, Zhefang Wang, Jiahui Li, Xiaolin Wu, Ningbo Fan, Dai Li, Fanyu Liu, Patrick S Plum, Sascha Hoppe, Axel M Hillmer, Alexandar Quaas, Florian Gebauer, Seung-Hun Chon, Christiane J Bruns, Yue Zhao

Journal: Cancers (Basel)

PubMed ID: 34065695

Doi: 10.3390/cancers13102403

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Single Cell Transcriptomic Analyses Reveal the Impact of bHLH Factors on Human Retinal Organoid Development

Authors: Xiangmei Zhang, Igor Mandric, Kevin H Nguyen, Thao T T Nguyen, Matteo Pellegrini, James C R Grove, Steven Barnes, Xian-Jie Yang

Journal: Front Cell Dev Biol

PubMed ID: 34055784

Doi: 10.3389/fcell.2021.653305

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Cardiac Late Sodium Channel Current Is a Molecular Target for the Sodium/Glucose Cotransporter 2 Inhibitor Empagliflozin

Authors: Koenraad Philippaert, Subha Kalyaanamoorthy, Mohammad Fatehi, Wentong Long, Shubham Soni, Nikole J Byrne, Amy Barr, Jyoti Singh, Jordan Wong, Taylor Palechuk, Chloe Schneider, Ahmed M Darwesh, Zaid H Maayah, John M Seubert, Khaled Barakat, Jason R B Dyck, Peter E Light

Journal: Circulation

PubMed ID: 33832341

Doi: 10.1161/CIRCULATIONAHA.121.053350

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Novel serine/threonine-O-glycosylation with N-acetylneuraminic acid and 3-deoxy-D-manno-octulosonic acid by bacterial flagellin glycosyltransferases

Authors: Khairnar A, Sunsunwal S, Babu P, Ramya TNC

Journal: Glycobiology

PubMed ID: 32886756

Doi: 10.1093/glycob/cwaa084

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Signal transduction through Cys-loop receptors is mediated by the nonspecific bumping of closely apposed domains

Authors: Gisela D Cymes, Claudio Grosman

Journal: Proc Natl Acad Sci U S A

PubMed ID: 33785596

Doi: 10.1073/pnas.2021016118

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Deficiency of macrophage PHACTR1 impairs efferocytosis and promotes atherosclerotic plaque necrosis

Authors: Canan Kasikara, Maaike Schilperoort, Brennan Gerlach, Chenyi Xue, Xiaobo Wang, Ze Zheng, George Kuriakose, Bernhard Dorweiler, Hanrui Zhang, Gabrielle Fredman, Danish Saleheen, Muredach P Reilly, Ira Tabas

Journal: J Clin Invest

PubMed ID: 33630758

Doi: 10.1172/JCI145275

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Janus Kinase 3 Deficiency Promotes Vascular Reendothelialization-Brief Report

Authors: Yung-Chun Wang, Dunpeng Cai, Xiao-Bing Cui, Ya-Hui Chuang, William P Fay, Shi-You Chen

Journal: Arterioscler Thromb Vasc Biol

PubMed ID: 33910370

Doi: 10.1161/ATVBAHA.121.316293

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FRET-based Microscopy Assay to Measure Activity of Membrane Amino Acid Transporters with Single-transporter Resolution

Authors: Didar Ciftci, Gerard H M Huysmans, Xiaoyu Wang, Changhao He, Daniel Terry, Zhou Zhou, Gabriel Fitzgerald, Scott C Blanchard, Olga Boudker

Journal: Bio Protoc

PubMed ID: 33889664

Doi: 10.21769/BioProtoc.3970

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The final step of 40S ribosomal subunit maturation is controlled by a dual key lock

Authors: Laura Plassart, Ramtin Shayan, Christian Montellese, Dana Rinaldi, Natacha Larburu, Carole Pichereaux, Carine Froment, Simon Lebaron, Marie-Françoise O'Donohue, Ulrike Kutay, Julien Marcoux, Pierre-Emmanuel Gleizes, Celia Plisson-Chastang

Journal: Elife

PubMed ID: 33908345

Doi: 10.7554/eLife.61254

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CLK1/SRSF5 pathway induces aberrant exon skipping of METTL14 and Cyclin L2 and promotes growth and metastasis of pancreatic cancer

Authors: Shi Chen, Can Yang, Zu-Wei Wang, Jian-Fei Hu, Jing-Jing Pan, Cheng-Yu Liao, Jia-Qiang Zhang, Jiang-Zhi Chen, Yi Huang, Long Huang, Qian Zhan, Yi-Feng Tian, Bai-Yong Shen, Yao-Dong Wang

Journal: J Hematol Oncol

PubMed ID: 33849617

Doi: 10.1186/s13045-021-01072-8

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