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Analysis of diverse eukaryotes suggests the existence of an ancestral mitochondrial apparatus derived from the bacterial type II secretion system
Authors: Lenka Horváthová, Vojtěch Žárský, Tomáš Pánek, Romain Derelle, Jan Pyrih, Alžběta Motyčková, Veronika Klápšťová, Martina Vinopalová, Lenka Marková, Luboš Voleman, Vladimír Klimeš, Markéta Petrů, Zuzana Vaitová, Ivan Čepička, Klára Hryzáková, Karel Harant, Michael W Gray, Mohamed Chami, Ingrid Guilvout, Olivera Francetic, B Franz Lang, Čestmír Vlček, Anastasios D Tsaousis, Marek Eliáš, Pavel Doležal
Journal: Nat Commun
PubMed ID: 34011950
Doi: 10.1038/s41467-021-23046-7
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Aldo-Keto Reductase 1C3 Mediates Chemotherapy Resistance in Esophageal Adenocarcinoma via ROS Detoxification
Authors: Chenghui Zhou, Zhefang Wang, Jiahui Li, Xiaolin Wu, Ningbo Fan, Dai Li, Fanyu Liu, Patrick S Plum, Sascha Hoppe, Axel M Hillmer, Alexandar Quaas, Florian Gebauer, Seung-Hun Chon, Christiane J Bruns, Yue Zhao
Journal: Cancers (Basel)
PubMed ID: 34065695
Doi: 10.3390/cancers13102403
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Single Cell Transcriptomic Analyses Reveal the Impact of bHLH Factors on Human Retinal Organoid Development
Authors: Xiangmei Zhang, Igor Mandric, Kevin H Nguyen, Thao T T Nguyen, Matteo Pellegrini, James C R Grove, Steven Barnes, Xian-Jie Yang
Journal: Front Cell Dev Biol
PubMed ID: 34055784
Doi: 10.3389/fcell.2021.653305
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Cardiac Late Sodium Channel Current Is a Molecular Target for the Sodium/Glucose Cotransporter 2 Inhibitor Empagliflozin
Authors: Koenraad Philippaert, Subha Kalyaanamoorthy, Mohammad Fatehi, Wentong Long, Shubham Soni, Nikole J Byrne, Amy Barr, Jyoti Singh, Jordan Wong, Taylor Palechuk, Chloe Schneider, Ahmed M Darwesh, Zaid H Maayah, John M Seubert, Khaled Barakat, Jason R B Dyck, Peter E Light
Journal: Circulation
PubMed ID: 33832341
Doi: 10.1161/CIRCULATIONAHA.121.053350
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Novel serine/threonine-O-glycosylation with N-acetylneuraminic acid and 3-deoxy-D-manno-octulosonic acid by bacterial flagellin glycosyltransferases
Authors: Khairnar A, Sunsunwal S, Babu P, Ramya TNC
Journal: Glycobiology
PubMed ID: 32886756
Doi: 10.1093/glycob/cwaa084
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Signal transduction through Cys-loop receptors is mediated by the nonspecific bumping of closely apposed domains
Authors: Gisela D Cymes, Claudio Grosman
Journal: Proc Natl Acad Sci U S A
PubMed ID: 33785596
Doi: 10.1073/pnas.2021016118
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Deficiency of macrophage PHACTR1 impairs efferocytosis and promotes atherosclerotic plaque necrosis
Authors: Canan Kasikara, Maaike Schilperoort, Brennan Gerlach, Chenyi Xue, Xiaobo Wang, Ze Zheng, George Kuriakose, Bernhard Dorweiler, Hanrui Zhang, Gabrielle Fredman, Danish Saleheen, Muredach P Reilly, Ira Tabas
Journal: J Clin Invest
PubMed ID: 33630758
Doi: 10.1172/JCI145275
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Janus Kinase 3 Deficiency Promotes Vascular Reendothelialization-Brief Report
Authors: Yung-Chun Wang, Dunpeng Cai, Xiao-Bing Cui, Ya-Hui Chuang, William P Fay, Shi-You Chen
Journal: Arterioscler Thromb Vasc Biol
PubMed ID: 33910370
Doi: 10.1161/ATVBAHA.121.316293
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FRET-based Microscopy Assay to Measure Activity of Membrane Amino Acid Transporters with Single-transporter Resolution
Authors: Didar Ciftci, Gerard H M Huysmans, Xiaoyu Wang, Changhao He, Daniel Terry, Zhou Zhou, Gabriel Fitzgerald, Scott C Blanchard, Olga Boudker
Journal: Bio Protoc
PubMed ID: 33889664
Doi: 10.21769/BioProtoc.3970
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CLK1/SRSF5 pathway induces aberrant exon skipping of METTL14 and Cyclin L2 and promotes growth and metastasis of pancreatic cancer
Authors: Shi Chen, Can Yang, Zu-Wei Wang, Jian-Fei Hu, Jing-Jing Pan, Cheng-Yu Liao, Jia-Qiang Zhang, Jiang-Zhi Chen, Yi Huang, Long Huang, Qian Zhan, Yi-Feng Tian, Bai-Yong Shen, Yao-Dong Wang
Journal: J Hematol Oncol
PubMed ID: 33849617
Doi: 10.1186/s13045-021-01072-8
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