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Mitochondrial CMPK2 mediates immunomodulatory and antiviral activities through IFN-dependent and IFN-independent pathways

Authors: Jenn-Haung Lai, De-Wei Wu, Chien-Hsiang Wu, Li-Feng Hung, Chuan-Yueh Huang, Shuk-Man Ka, Ann Chen, Zee-Fen Chang, Ling-Jun Ho

Journal: iScience

PubMed ID: 34142025

Doi: 10.1016/j.isci.2021.102498

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YWHAE-NUTM2 oncoprotein regulates proliferation and cyclin D1 via RAF/MAPK and Hippo pathways

Authors: Wen-Bin Ou, Meijun Z Lundberg, Shuihao Zhu, Nacef Bahri, Anastasios Kyriazoglou, Liangliang Xu, Ting Chen, Adrian Mariño-Enriquez, Jonathan A Fletcher

Journal: Oncogenesis

PubMed ID: 33947829

Doi: 10.1038/s41389-021-00327-w

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Nanomolar Pulse Dipolar EPR Spectroscopy in Proteins: Cu-Cu and Nitroxide-Nitroxide Cases

Authors: Katrin Ackermann, Joshua L Wort, Bela E Bode

Journal: J Phys Chem B

PubMed ID: 33998795

Doi: 10.1021/acs.jpcb.1c03666

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Direct Observation of the Self-Aggregation of R3R4 Bi-repeat of Tau Protein

Authors: Parvathy Jayan, Arshad A Vahid, Safwa T Kizhakkeduth, Shafeek O H Muhammed, Ajmala B Shibina, Vinesh Vijayan

Journal: Chembiochem

PubMed ID: 33826208

Doi: 10.1002/cbic.202100013

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The antiviral enzyme viperin inhibits cholesterol biosynthesis

Authors: Timothy J Grunkemeyer, Soumi Ghosh, Ayesha M Patel, Keerthi Sajja, James Windak, Venkatesha Basrur, Youngsoo Kim, Alexey I Nesvizhskii, Robert T Kennedy, E Neil G Marsh

Journal: J Biol Chem

PubMed ID: 34029588

Doi: 10.1016/j.jbc.2021.100824

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SpRY Cas9 Can Utilize a Variety of Protospacer Adjacent Motif Site Sequences To Edit the Candida albicans Genome

Authors: Ben A Evans, Douglas A Bernstein

Journal: mSphere

PubMed ID: 34011687

Doi: 10.1128/mSphere.00303-21

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Reenacting the Birth of a Function: Functional Divergence of HIUases and Transthyretins as Inferred by Evolutionary and Biophysical Studies

Authors: Lucas Carrijo de Oliveira, Mariana Amalia Figueiredo Costa, Natan Gonçalves Pedersolli, Fernanda Aparecida Heleno Batista, Ana Carolina Migliorini Figueira, Rafaela Salgado Ferreira, Ronaldo Alves Pinto Nagem, Laila Alves Nahum, Lucas Bleicher

Journal: J Mol Evol

PubMed ID: 33956179

Doi: 10.1007/s00239-021-10010-8

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Human Immunodeficiency Viruses Pseudotyped with SARS-CoV-2 Spike Proteins Infect a Broad Spectrum of Human Cell Lines through Multiple Entry Mechanisms

Authors: Chuan Xu, Annie Wang, Ke Geng, William Honnen, Xuening Wang, Natalie Bruiners, Sukhwinder Singh, Fortunato Ferrara, Sara D'Angelo, Andrew R M Bradbury, Maria Laura Gennaro, Dongfang Liu, Abraham Pinter, Theresa L Chang

Journal: Viruses

PubMed ID: 34064066

Doi: 10.3390/v13060953

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Knockdown of ANXA10 inhibits proliferation and promotes apoptosis of papillary thyroid carcinoma cells by down-regulating TSG101 thereby inactivating the MAPK/ERK signaling pathway

Authors: Tianjun Wei, Xiangming Zhu

Journal: J Bioenerg Biomembr

PubMed ID: 34032966

Doi: 10.1007/s10863-021-09902-7

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Structural basis of tetanus toxin neutralization by native human monoclonal antibodies

Authors: Yueming Wang, Changwen Wu, Jinfang Yu, Shujian Lin, Tong Liu, Lipeng Zan, Nan Li, Po Hong, Xiaoli Wang, Zhenxing Jia, Jason Li, Yao Wang, Ming Zhang, Xiaohui Yuan, Chengming Li, Wenwen Xu, Weihong Zheng, Xinquan Wang, Hua-Xin Liao

Journal: Cell Rep

PubMed ID: 33951441

Doi: 10.1016/j.celrep.2021.109070

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