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Robust, persistent adaptive immune responses to SARS-CoV-2 in the oropharyngeal lymphoid tissue of children

Authors: Kalpana Manthiram, Qin Xu, Pedro Milanez-Almeida, Andrew Martins, Andrea Radtke, Kenneth Hoehn, Jinguo Chen, Can Liu, Juanjie Tang, Gabrielle Grubbs, Sydney Stein, Sabrina Ramelli, Juraj Kabat, Hengameh Behzadpour, Maria Karkanitsa, Jacquelyn Spathies, Heather Kalish, Lela Kardava, Martha Kirby, Foo Cheung, Silvia Preite, Patrick Duncker, Nahir Romero, Diego Preciado, Lyuba Gitman, Galina Koroleva, Grace Smith, Arthur Shaffer, Ian McBain, Stefania Pittaluga, Ronald Germain, Richard Apps, Kaitlyn Sadtler, Susan Moir, Daniel Chertow, Steven Kleinstein, Surender Khurana, John Tsang, Pamela Mudd, Pamela Schwartzberg

Journal: Res Sq

PubMed ID: 35350206

Doi: 10.21203/rs.3.rs-1276578/v1

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Monomodular Pseudomonas aeruginosa phage JG004 lysozyme (Pae87) contains a bacterial surface-active antimicrobial peptide-like region and a possible substrate-binding subdomain

Authors: Roberto Vázquez, Mateo Seoane-Blanco, Virginia Rivero-Buceta, Susana Ruiz, Mark J van Raaij, Pedro García

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 35362467

Doi: 10.1107/S2059798322000936

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KIR3DL05 and KIR3DS02 Recognition of a Nonclassical MHC Class I Molecule in the Rhesus Macaque Implicated in Pregnancy Success

Authors: Rachel E Nicholas, Kjell Sandstrom, Jennifer L Anderson, Willow R Smith, Molly Wetzel, Priyankana Banerjee, Sanath Kumar Janaka, David T Evans

Journal: Front Immunol

PubMed ID: 35401580

Doi: 10.3389/fimmu.2022.841136

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A mixed-valent Fe(II)Fe(III) species converts cysteine to an oxazolone/thioamide pair in methanobactin biosynthesis

Authors: Yun Ji Park, Richard J Jodts, Jeffrey W Slater, Reyvin M Reyes, Valerie J Winton, Rana A Montaser, Paul M Thomas, William B Dowdle, Anahi Ruiz, Neil L Kelleher, J Martin Bollinger, Carsten Krebs, Brian M Hoffman, Amy C Rosenzweig

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35320042

Doi: 10.1073/pnas.2123566119

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OvoA from ovothiol biosynthesis is a bifunction enzyme: thiol oxygenase and sulfoxide synthase activities

Authors: Ronghai Cheng, Andrew C Weitz, Jared Paris, Yijie Tang, Jingyu Zhang, Heng Song, Nathchar Naowarojna, Kelin Li, Lu Qiao, Juan Lopez, Mark W Grinstaff, Lixin Zhang, Yisong Guo, Sean Elliott, Pinghua Liu

Journal: Chem Sci

PubMed ID: 35432880

Doi: 10.1039/d1sc05479a

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MicroRNA-378 contributes to osteoarthritis by regulating chondrocyte autophagy and bone marrow mesenchymal stem cell chondrogenesis

Authors: Lu Feng, Zhengmeng Yang, Yucong Li, Qi Pan, Xiaoting Zhang, Xiaomin Wu, Jessica Hiu Tung Lo, Haixing Wang, Shanshan Bai, Xuan Lu, Ming Wang, Sien Lin, Xiaohua Pan, Gang Li

Journal: Mol Ther Nucleic Acids

PubMed ID: 35474736

Doi: 10.1016/j.omtn.2022.03.016

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Method for quantification of porcine type I interferon activity using luminescence, by direct and indirect means

Authors: Michael Puckette, J Barrera, M Schwarz, M Rasmussen

Journal: BMC Biotechnol

PubMed ID: 35351081

Doi: 10.1186/s12896-022-00743-9

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Systematic Discovery of FBXW7-Binding Phosphodegrons Highlights Mitogen-Activated Protein Kinases as Important Regulators of Intracellular Protein Levels

Authors: Neha Singh, András Zeke, Attila Reményi

Journal: Int J Mol Sci

PubMed ID: 35328741

Doi: 10.3390/ijms23063320

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Physical Interaction between Cyclin-Dependent Kinase 5 (CDK5) and Clock Factors Affects the Circadian Rhythmicity in Peripheral Oscillators

Authors: Jürgen A Ripperger, Rohit Chavan, Urs Albrecht, Andrea Brenna

Journal: Clocks Sleep

PubMed ID: 35323171

Doi: 10.3390/clockssleep4010017

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Structural and functional characterizations of infectivity and immune evasion of SARS-COV-2Omicron

Authors: Zhen Cui, Pan Liu, Nan Wang, Lei Wang, Kaiyue Fan, Qianhui Zhu, Kang Wang, Ruihong Chen, Rui Feng, Zijing Jia, Minnan Yang, Ge Xu, Boling Zhu, Wangjun Fu, Tianming Chu, Leilei Feng, Yide Wang, Xinran Pei, Peng Yang, Xiaoliang Sunney Xie, Lei Cao, Yunlong Cao, Xiangxi Wang

Journal: Cell

PubMed ID: 35120603

Doi: 10.1016/j.cell.2022.01.019

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