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Non-ionic detergent assists formation of supercharged nanodiscs and insertion of membrane proteins
Authors: Frederik G Tidemand, Sara Blemmer, Nicolai T Johansen, Lise Arleth, Martin Cramer Pedersen
Journal: Biochim Biophys Acta Biomembr
PubMed ID: 35182589
Doi: 10.1016/j.bbamem.2022.183884
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TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A
Authors: X Rosa Ma, Mercedes Prudencio, Yuka Koike, Sarat C Vatsavayai, Garam Kim, Fred Harbinski, Adam Briner, Caitlin M Rodriguez, Caiwei Guo, Tetsuya Akiyama, H Broder Schmidt, Beryl B Cummings, David W Wyatt, Katherine Kurylo, Georgiana Miller, Shila Mekhoubad, Nathan Sallee, Gemechu Mekonnen, Laura Ganser, Jack D Rubien, Karen Jansen-West, Casey N Cook, Sarah Pickles, Björn Oskarsson, Neill R Graff-Radford, Bradley F Boeve, David S Knopman, Ronald C Petersen, Dennis W Dickson, James Shorter, Sua Myong, Eric M Green, William W Seeley, Leonard Petrucelli, Aaron D Gitler
Journal: Nature
PubMed ID: 35197626
Doi: 10.1038/s41586-022-04424-7
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DNA Vaccines Expressing the Envelope and Membrane Proteins Provide Partial Protection Against SARS-CoV-2 in Mice
Authors: Jinni Chen, Yao Deng, Baoying Huang, Di Han, Wen Wang, Mengjing Huang, Chengcheng Zhai, Zhimin Zhao, Ren Yang, Ying Zhao, Wenling Wang, Desheng Zhai, Wenjie Tan
Journal: Front Immunol
PubMed ID: 35281016
Doi: 10.3389/fimmu.2022.827605
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Deciphering the Molecular Mechanism of HCV Protease Inhibitor Fluorination as a General Approach to Avoid Drug Resistance
Authors: Jacqueto Zephyr, Desaboini Nageswara Rao, Sang V Vo, Mina Henes, Klajdi Kosovrasti, Ashley N Matthew, Adam K Hedger, Jennifer Timm, Elise T Chan, Akbar Ali, Nese Kurt Yilmaz, Celia A Schiffer
Journal: J Mol Biol
PubMed ID: 35183560
Doi: 10.1016/j.jmb.2022.167503
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Evaluation of Hydroxycarboxylic Acid Receptor 1 (HCAR1) as a Building Block for Genetically Encoded Extracellular Lactate Biosensors
Authors: Joel Wellbourne-Wood, Marc Briquet, Maxime Alessandri, Francesca Binda, Maylis Touya, Jean-Yves Chatton
Journal: Biosensors (Basel)
PubMed ID: 35323413
Doi: 10.3390/bios12030143
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From musk to body odor: Decoding olfaction through genetic variation
Authors: Bingjie Li, Marissa L Kamarck, Qianqian Peng, Fei-Ling Lim, Andreas Keller, Monique A M Smeets, Joel D Mainland, Sijia Wang
Journal: PLoS Genet
PubMed ID: 35113854
Doi: 10.1371/journal.pgen.1009564
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Identification, functional characterization, assembly and structure of ToxIN type III toxin-antitoxin complex from E coli
Authors: Parthasarathy Manikandan, Sankaran Sandhya, Kavyashree Nadig, Souradip Paul, Narayanaswamy Srinivasan, Ulli Rothweiler, Mahavir Singh
Journal: Nucleic Acids Res
PubMed ID: 35018473
Doi: 10.1093/nar/gkab1264
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Genome-wide association study and functional follow-up identifies 14q12 as a candidate risk locus for cervical cancer
Authors: Dhanya Ramachandran, Joe Dennis, Laura Fachal, Peter Schürmann, Kristine Bousset, Fabienne Hülse, Qianqian Mao, Yingying Wang, Matthias Jentschke, Gerd Böhmer, Hans-Georg Strauß, Christine Hirchenhain, Monika Schmidmayr, Florian Müller, Ingo Runnebaum, Alexander Hein, Frederik Stübs, Martin Koch, Matthias Ruebner, Matthias W Beckmann, Peter A Fasching, Alexander Luyten, Matthias Dürst, Peter Hillemanns, Douglas F Easton, Thilo Dörk
Journal: Hum Mol Genet
PubMed ID: 35157032
Doi: 10.1093/hmg/ddac031
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Development of a Nanoparticle Multiepitope DNA Vaccine against Virulent Infectious Bronchitis Virus Challenge
Authors: Yifeng Qin, Qingyuan Teng, Delan Feng, Yu Pei, Ye Zhao, Guozhong Zhang
Journal: J Immunol
PubMed ID: 35217582
Doi: 10.4049/jimmunol.2100909
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Enzymatic activity of glycosyltransferase GLT8D1 promotes human glioblastoma cell migration
Authors: Elena I Ilina, Camille Cialini, Dietlind L Gerloff, Maitane Duarte Garcia-Escudero, Céline Jeanty, Marie-Laëtitia Thézénas, Antoine Lesur, Vincent Puard, François Bernardin, Alina Moter, Anne Schuster, Monika Dieterle, Anna Golebiewska, Jean-Jacques Gérardy, Gunnar Dittmar, Simone P Niclou, Tanja Müller, Michel Mittelbronn
Journal: iScience
PubMed ID: 35198895
Doi: 10.1016/j.isci.2022.103842
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