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Kinetic Characterization and Inhibition of Hypoxanthine-Guanine Phosphoribosyltransferases

Authors: Kayla Glockzin, Demetrios Kostomiris, Yacoba V T Minnow, Kajitha Suthagar, Keith Clinch, Sinan Gai, Joshua N Buckler, Vern L Schramm, Peter C Tyler, Thomas D Meek, Ardala Katzfuss

Journal: Biochemistry

PubMed ID: 36193631

Doi: 10.1021/acs.biochem.2c00312

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PGAM1 Promotes Glycolytic Metabolism and Paclitaxel Resistance via Pyruvic Acid Production in Ovarian Cancer Cells

Authors: Yan Feng, Xu Zhang, Songfa Zhang, Shanshan Xu, Xiaojing Chen, Caiyun Zhou, Yongmei Xi, Xing Xie, Weiguo Lu

Journal: Front Biosci (Landmark Ed)

PubMed ID: 36224008

Doi: 10.31083/j.fbl2709262

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The design of protozoan phosphoribosyltransferase inhibitors containing non-charged phosphate mimic residues

Authors: Sinan Gai, Kajitha Suthagar, Karl J Shaffer, Wanting Jiao, Yacoba V T Minnow, Kayla Glockzin, Sean W Maatouk, Ardala Katzfuss, Thomas D Meek, Vern L Schramm, Peter C Tyler

Journal: Bioorg Med Chem

PubMed ID: 36209571

Doi: 10.1016/j.bmc.2022.117038

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Utilization of Receptor-Binding Domain of SARS-CoV-2 Spike Protein Expressed in Escherichia coli for the Development of Neutralizing Antibody Assay

Authors: Termsak Tantiwiwat, Apisitt Thaiprayoon, Ake-Kavitch Siriatcharanon, Chakrit Tachaapaikoon, Nongluk Plongthongkum, Dujduan Waraho-Zhmayev

Journal: Mol Biotechnol

PubMed ID: 36103078

Doi: 10.1007/s12033-022-00563-4

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Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1

Authors: Callum Beach; David MacLean; Dominika Majorova; Stavros Melemenidis; Dhanya K. Nambiar; Ryan K. Kim; Gabriel N. Valbuena; Silvia Guglietta; Carsten Krieg; Mahnaz Darvish-Damavandi; Tatsuya Suwa; Alistair Easton; Lily V.S. Hillson; Ashley K. McCulloch; Ross K. McMahon; Kathryn Pennel; Joanne Edwards; Sean M. O Cathail; Campbell S. Roxburgh; Enric Domingo; Eui Jung Moon; Dadi Jiang; Yanyan Jiang; Qingyang Zhang; Albert C. Koong; Trent M. Woodruff; Edward E. Graves; Tim Maughan; Simon J.A. Buczacki; Manuel Stucki; Quynh-Thu Le; Simon J. Leedham; Amato J. Giaccia; Monica M. Olcina

Journal: The Journal of clinical investigation

PubMed ID: 37824211

Doi: 10.1172/JCI168277

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Allelic polymorphism controls autoreactivity and vaccine elicitation of human broadly neutralizing antibodies against influenza virus

Authors: Maya Sangesland, Alba Torrents de la Peña, Seyhan Boyoglu-Barnum, Larance Ronsard, Faez Amokrane Nait Mohamed, Thalia Bracamonte Moreno, Ralston M Barnes, Daniel Rohrer, Nils Lonberg, Musie Ghebremichael, Masaru Kanekiyo, Andrew Ward, Daniel Lingwood

Journal: Immunity

PubMed ID: 35952670

Doi: 10.1016/j.immuni.2022.07.006

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Expression of ENaC subunits in epithelia

Authors: Gustavo Frindt, Joel R Meyerson, Alexandra Satty, Joseph M Scandura, Lawrence G Palmer

Journal: J Gen Physiol

PubMed ID: 35939271

Doi: 10.1085/jgp.202213124

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miR-657 Targets SRCIN1 via the Slug Pathway to Promote NSCLC Tumor Growth and EMT Induction

Authors: Yingqian Zhang, Jiao Yuan, Mengfei Guo, Run Xiang, Xiang Wang, Tianpeng Xie, Xiang Zhuang, Qiang Li, Qi Lai

Journal: Dis Markers

PubMed ID: 36033827

Doi: 10.1155/2022/4842454

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Integrated AlphaFold2 and DEER investigation of the conformational dynamics of a pH-dependent APC antiporter

Authors: Diego Del Alamo, Lillian DeSousa, Rahul M Nair, Suhaila Rahman, Jens Meiler, Hassane S Mchaourab

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35969794

Doi: 10.1073/pnas.2206129119

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A novel ZsGreen knock-in melanoma cell line reveals the function of CD11b in tumor phagocytosis

Authors: Lichen Zhang, Xinyu Feng, Yingzhuo Shen, Yingbin Wang, Zhuangzhuang Liu, Yuang Ma, Yanrong Gu, Guo Guo, Liangwei Duan, Liaoxun Lu, Yinming Liang, Toby Lawrence, Rong Huang

Journal: Immunol Cell Biol

PubMed ID: 35849045

Doi: 10.1111/imcb.12575

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