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Phosphorylation-inducing chimera rewires oncogenic kinase to trigger apoptosis
Authors: Manuel L. Merz; Veronika M. Shoba; Rajaiah Pergu; Zachary C. Severance; Dhanushka N. P. Munkanatta Godage; Arghya Deb; Hui Si Kwok; Prashant Singh; Sameek Singh; Jonathan B. Allen; Wenzhi Tian; Pallavi M. Gosavi; Santosh K. Chaudhary; Viktoriya Anokhina; Ellen L. Weisberg; N. Connor Payne; Yao He; Reilly Osadchey; Mrinal Shekhar; Ralph Mazitschek; Matthew G. Rees; Jennifer A. Roth; Qiang Cui; James D. Griffin; Brian B. Liau; Amit Choudhary
Journal: biorxiv
PubMed ID: 40661463
Doi: 10.1101/2025.06.13.659082
Products & Services: PCR Cloning and Subcloning   
Phosphorylation-inducing chimera rewires oncogenic kinase to trigger apoptosis
Authors: Manuel L. Merz; Veronika M. Shoba; Rajaiah Pergu; Zachary C. Severance; Dhanushka N. P. Munkanatta Godage; Arghya Deb; Hui Si Kwok; Prashant Singh; Sameek Singh; Jonathan B. Allen; Wenzhi Tian; Pallavi M. Gosavi; Santosh K. Chaudhary; Viktoriya Anokhina; Ellen L. Weisberg; N. Connor Payne; Yao He; Reilly Osadchey; Mrinal Shekhar; Ralph Mazitschek; Matthew G. Rees; Jennifer A. Roth; Qiang Cui; James D. Griffin; Brian B. Liau; Amit Choudhary
Journal: biorxiv
PubMed ID: 40661463
Doi: 10.1101/2025.06.13.659082
Products & Services: PCR Cloning and Subcloning   
Designing Sandwich ELISA with Broadly Reactive Anti-Nucleocapsid Monoclonal Antibodies to Detect Bat-Borne Merbecoviruses
Authors: Kong Yen Liew, Yaju Wang, Sneha Sree Mullapudi, Dinah Binte Aziz, Wenjie Fan, Min Luo, Paul Anantharajah Tambyah, Yee-Joo Tan
Journal: Viruses
PubMed ID: 40733504
Doi: 10.3390/v17070886
Products & Services: Gene Synthesis   Codon Optimization   PCR Cloning and Subcloning   
Identification and characterisation of vaginal bacteria-glycan interactions implicated in reproductive tract health and pregnancy outcomes
Authors: Virginia Tajadura-Ortega, Wengang Chai, Lauren A Roberts, Yibing Zhang, Antonio Di Maio, Alexiane C Decout, Benedita A Pinheiro, Angelina S Palma, Gian De Nicola, Lucia Riaposova, Belen Gimeno-Molina, Yun S Lee, Hongzhi Cao, Vladimir Piskarev, Yukie Akune, Tiago R D Costa, Himani Amin, Lynne Sykes, Phillip R Bennett, Julian R Marchesi, Ten Feizi, Yan Liu, David A MacIntyre
Journal: Nature Communications
PubMed ID: 40467588
Doi: 10.1038/s41467-025-60404-1
Products & Services: PCR Cloning and Subcloning   
Strategy to overcome a nirmatrelvir resistance mechanism in the SARS-CoV-2 nsp5 protease
Authors: Grace Neilsen, Shuiyun Lan, Ryan L Slack, Zachary C Lorson, Andres Emanuelli Castaner, Rachel Lee, Kristin G Edwards, Huanchun Zhang, Jasper Lee, William A Cantara, Maria E Cilento, Hongwang Zhang, Ramyani De, Franck Amblard, Philip R Tedbury, Karen A Kirby, Raymond F Schinazi, Stefan G Sarafianos
Journal: SCIENCE ADVANCES
PubMed ID: 40479048
Doi: 10.1126/sciadv.adv8875
Products & Services: PCR Cloning and Subcloning   
UniClo: scarless hierarchical DNA assembly without sequence constraint
Authors: Carol N Flores-Fernández , Da Lin , Katherine Robins , Chris A O'Callaghan
Journal: Nucleic Acids Research
PubMed ID: 40548934
Doi: 10.1093/nar/gkaf548
Products & Services: PCR Cloning and Subcloning   
Phosphorylation-inducing chimera rewires oncogenic kinase to trigger apoptosis
Authors: Manuel L. Merz; Veronika M. Shoba; Rajaiah Pergu; Zachary C. Severance; Dhanushka N. P. Munkanatta Godage; Arghya Deb; Hui Si Kwok; Prashant Singh; Sameek Singh; Jonathan B. Allen; Wenzhi Tian; Pallavi M. Gosavi; Santosh K. Chaudhary; Viktoriya Anokhina; Ellen L. Weisberg; N. Connor Payne; Yao He; Reilly Osadchey; Mrinal Shekhar; Ralph Mazitschek; Matthew G. Rees; Jennifer A. Roth; Qiang Cui; James D. Griffin; Brian B. Liau; Amit Choudhary
Journal: biorxiv
PubMed ID: 40661463
Doi: 10.1101/2025.06.13.659082
Products & Services: PCR Cloning and Subcloning   
Phosphorylation-inducing chimera rewires oncogenic kinase to trigger apoptosis
Authors: Manuel L. Merz; Veronika M. Shoba; Rajaiah Pergu; Zachary C. Severance; Dhanushka N. P. Munkanatta Godage; Arghya Deb; Hui Si Kwok; Prashant Singh; Sameek Singh; Jonathan B. Allen; Wenzhi Tian; Pallavi M. Gosavi; Santosh K. Chaudhary; Viktoriya Anokhina; Ellen L. Weisberg; N. Connor Payne; Yao He; Reilly Osadchey; Mrinal Shekhar; Ralph Mazitschek; Matthew G. Rees; Jennifer A. Roth; Qiang Cui; James D. Griffin; Brian B. Liau; Amit Choudhary
Journal: biorxiv
PubMed ID: 40661463
Doi: 10.1101/2025.06.13.659082
Products & Services: PCR Cloning and Subcloning   
Synthesis of an E2-Ub-nucleosome conjugate to capture the E3 ligase PHF7-catalyzed H3K14 ubiquitination intermediate
Authors: Shixian Tao, Wei He, Chuntong Li, Jiawei Liang, Zebin Tong, Zhiheng Deng, Liying Zhang, Huasong Ai, Lu-Jun Liang, Lei Liu
Journal: Science China-Chemistry
Doi: 10.1007/s11426-025-2697-6
Products & Services: PCR Cloning and Subcloning   
Single-Cell and Spatial Transcriptomic Profiling of Penile Squamous Cell Carcinoma Reveals Dynamics of Tumor Differentiation and Immune Microenvironment
Authors: Hongjian Song, Zhichao Tong, Guixiang Xie, Yaowei Li, Yubo Zhao, Fengpu Fan, Zongzheng Yang, Qing Shi, Qian Zhang, Feng Wen, Hongxue Meng, Haonan Li, Pengyu Guo, Dayong Hou, Zhenwei Zhang, Zhihao Yin, Ziyi Liu, Jianwei Wang, Peng Zhang, Peng Dai, Changfu Li, Lichen Teng, Yangyang Xu, Dexin Ding, Tao Xu, Jianzhang Li, Yongsheng Chen, Yu Qiu, XiaoWei Hu, Wentao Liu, Liang Wu, Roman Nawroth, Guibo Li, Hang Su, Ziqing Deng, Ziqi Wang, Di Wang, Wanhai Xu
Journal: Advanced Science
PubMed ID: 40470730
Doi: 10.1002/advs.202500216
Products & Services: PCR Cloning and Subcloning   
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