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An integrated electrochemical nanodevice for single-cell MiRNA-155 detection and drug evaluation

Authors: Zhuo Li , Zhaohan Wang , Jun Chen , Yafeng Wu

Journal: BIOSENSORS & BIOELECTRONICS

PubMed ID: 40695112

Doi: 10.1016/j.bios.2025.117804

Products & Services: PCR Cloning and Subcloning

Localized Delivery of the mRNAs Encoding CD47 Inhibitor and Interleukins 12, 15, and 21 Elicits Robust Antitumor Immunity

Authors: Tao Jiang, Shuaiyang Jing, Haojun Li, Bao Xiao, Jiahui Jin, Xiu Sun, Juan Wang, Jing Liang, Tongze Cai, Huili Hu, Meilan Wei, Xuanrui Zhong, Yang Ji, Peng George Wang, Jianlong Zhou

Journal: Advanced Science

PubMed ID: 40652522

Doi: 10.1002/advs.202417205

Products & Services: PCR Cloning and Subcloning

Precision-edited histone tails disrupt polycistronic gene expression controls in trypanosomes

Authors: Markéta Novotná, Michele Tinti, Joana R C Faria, David Horn

Journal: Nature Communications

PubMed ID: 40615444

Doi: 10.1038/s41467-025-61480-z

Products & Services: PCR Cloning and Subcloning

Rewiring endogenous genes in CAR T cells for tumour-restricted payload delivery

Authors: Amanda X Y Chen, Kah Min Yap, Joelle S Kim, Kevin Sek, Yu-Kuan Huang, Phoebe A Dunbar, Volker Wiebking, Jesse D Armitage, Isabelle Munoz, Kirsten L Todd, Emily B Derrick, Dat Nguyen, Junming Tong, Cheok Weng Chan, Thang X Hoang, Katherine M Audsley, Marit J van Elsas, Jim Middelburg, Joel N Lee, Maria N de Menezes, Thomas J Cole, Jasmine Li, Christina Scheffler, Andrew M Scott, Laura K Mackay, Jason Waithman, Jane Oliaro, Simon J Harrison, Ian A Parish, Junyun Lai, Matthew H Porteus, Imran G House, Phillip K Darcy, Paul A Beavis

Journal: Nature

PubMed ID: 40604285

Doi: 10.1038/s41586-025-09212-7

Products & Services: PCR Cloning and Subcloning

NXT2 is a key component of the RNA nuclear export factor complex in the human testis and essential for spermatogenesis

Authors: Ann-Kristin Dicke, Ammar Ahmedani, Lin Ma, Leonie Herrmann, Godfried W van der Heijden, Sophie A Koser, Claudia Krallmann, Oguzhan Kalyon, Miguel J Xavier, Joris A Veltman, Sabine Kliesch, Nina Neuhaus, Noora Kotaja, Frank Tüttelmann, Birgit Stallmeyer

Journal: Nature Communications

PubMed ID: 40624043

Doi: 10.1038/s41467-025-61463-0

Products & Services: PCR Cloning and Subcloning

Ion channel structure and function of the MERS coronavirus E protein

Authors: Iva Sučec, Bingqing Xia, Noah H Somberg, Yi Wang, Hyunil Jo, Shuangqu Li, Barbara Perrone, Zhaobing Gao, Mei Hong

Journal: SCIENCE ADVANCES

PubMed ID: 40632851

Doi: 10.1126/sciadv.adx1788

Products & Services: PCR Cloning and Subcloning

The defensome of prokaryotes in aquifers

Authors: Pengwei Li, Zongzhi Wu, Tang Liu, Chunfang Deng, Quan Liu, Jinren Ni

Journal: Nature Communications

PubMed ID: 40659683

Doi: 10.1038/s41467-025-61467-w

Products & Services: PCR Cloning and Subcloning

A post-assembly conformational change makes the SARS-CoV-2 polymerase elongation-competent

Authors: Misha Klein, Arnab Das, Subhas C Bera, Thomas K Anderson, Dana Kocincova, Hery W Lee, Bing Wang, Flavia S Papini, John C Marecki, Jamie J Arnold, Craig E Cameron, Kevin D Raney, Irina Artsimovitch, Mathias Götte, Robert N Kirchdoerfer, Martin Depken, David Dulin

Journal: Nucleic Acids Research

PubMed ID: 40464687

Doi: 10.1093/nar/gkaf450

Products & Services: PCR Cloning and Subcloning

Lysosomal TMEM165 controls cellular ion homeostasis and survival by mediating lysosomal Ca2+ import and H+ efflux

Authors: Ran Chen, Bin Liu, Dawid Jaślan, Lucija Kucej, Veronika Kudrina, Belinda Warnke, Yvonne E Klingl, Arnas Petrauskas, Sandra Prat Castro, Kenji Maeda, Christian Grimm, Marja Jäättelä

Journal: Nature Communications

PubMed ID: 40473625

Doi: 10.1038/s41467-025-60349-5

Products & Services: PCR Cloning and Subcloning

The TRIP12 E3 ligase induces SWI/SNF component BRG1-β-catenin interaction to promote Wnt signaling

Authors: Sara Kassel, Kai Yuan, Nawat Bunnag, Leif R Neitzel, Wenhui Lu, Anna Schwarzkopf, Benjamin Maines, Matthew A Loberg, George Xu, Amber Adams, Andrew D McCray, Alex Cho, Mary Rockouski, Gemma Orton, Lily Goldsmith, Md Mubtaseem Ahnaf Aronno, Zachary T Spencer, Omar M Khan, Fei Ye, Charles Williams, Andres M Lebensohn, Rajat Rohatgi, Xiaofeng Wang, Vivian L Weiss, Charles C Hong, Arminja N Kettenbach, David J Robbins, Yashi Ahmed, Ethan Lee

Journal: Nature Communications

PubMed ID: 40473626

Doi: 10.1038/s41467-025-60535-5

Products & Services: PCR Cloning and Subcloning