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Ion channel structure and function of the MERS coronavirus E protein

Authors: Iva Sučec, Bingqing Xia, Noah H Somberg, Yi Wang, Hyunil Jo, Shuangqu Li, Barbara Perrone, Zhaobing Gao, Mei Hong

Journal: SCIENCE ADVANCES

PubMed ID: 40632851

Doi: 10.1126/sciadv.adx1788

Products & Services: PCR Cloning and Subcloning

The defensome of prokaryotes in aquifers

Authors: Pengwei Li, Zongzhi Wu, Tang Liu, Chunfang Deng, Quan Liu, Jinren Ni

Journal: Nature Communications

PubMed ID: 40659683

Doi: 10.1038/s41467-025-61467-w

Products & Services: PCR Cloning and Subcloning

A post-assembly conformational change makes the SARS-CoV-2 polymerase elongation-competent

Authors: Misha Klein, Arnab Das, Subhas C Bera, Thomas K Anderson, Dana Kocincova, Hery W Lee, Bing Wang, Flavia S Papini, John C Marecki, Jamie J Arnold, Craig E Cameron, Kevin D Raney, Irina Artsimovitch, Mathias Götte, Robert N Kirchdoerfer, Martin Depken, David Dulin

Journal: Nucleic Acids Research

PubMed ID: 40464687

Doi: 10.1093/nar/gkaf450

Products & Services: PCR Cloning and Subcloning

The TRIP12 E3 ligase induces SWI/SNF component BRG1-β-catenin interaction to promote Wnt signaling

Authors: Sara Kassel, Kai Yuan, Nawat Bunnag, Leif R Neitzel, Wenhui Lu, Anna Schwarzkopf, Benjamin Maines, Matthew A Loberg, George Xu, Amber Adams, Andrew D McCray, Alex Cho, Mary Rockouski, Gemma Orton, Lily Goldsmith, Md Mubtaseem Ahnaf Aronno, Zachary T Spencer, Omar M Khan, Fei Ye, Charles Williams, Andres M Lebensohn, Rajat Rohatgi, Xiaofeng Wang, Vivian L Weiss, Charles C Hong, Arminja N Kettenbach, David J Robbins, Yashi Ahmed, Ethan Lee

Journal: Nature Communications

PubMed ID: 40473626

Doi: 10.1038/s41467-025-60535-5

Products & Services: PCR Cloning and Subcloning

Lysosomal TMEM165 controls cellular ion homeostasis and survival by mediating lysosomal Ca2+ import and H+ efflux

Authors: Ran Chen, Bin Liu, Dawid Jaślan, Lucija Kucej, Veronika Kudrina, Belinda Warnke, Yvonne E Klingl, Arnas Petrauskas, Sandra Prat Castro, Kenji Maeda, Christian Grimm, Marja Jäättelä

Journal: Nature Communications

PubMed ID: 40473625

Doi: 10.1038/s41467-025-60349-5

Products & Services: PCR Cloning and Subcloning

Identification and characterisation of vaginal bacteria-glycan interactions implicated in reproductive tract health and pregnancy outcomes

Authors: Virginia Tajadura-Ortega, Wengang Chai, Lauren A Roberts, Yibing Zhang, Antonio Di Maio, Alexiane C Decout, Benedita A Pinheiro, Angelina S Palma, Gian De Nicola, Lucia Riaposova, Belen Gimeno-Molina, Yun S Lee, Hongzhi Cao, Vladimir Piskarev, Yukie Akune, Tiago R D Costa, Himani Amin, Lynne Sykes, Phillip R Bennett, Julian R Marchesi, Ten Feizi, Yan Liu, David A MacIntyre

Journal: Nature Communications

PubMed ID: 40467588

Doi: 10.1038/s41467-025-60404-1

Products & Services: PCR Cloning and Subcloning

Strategy to overcome a nirmatrelvir resistance mechanism in the SARS-CoV-2 nsp5 protease

Authors: Grace Neilsen, Shuiyun Lan, Ryan L Slack, Zachary C Lorson, Andres Emanuelli Castaner, Rachel Lee, Kristin G Edwards, Huanchun Zhang, Jasper Lee, William A Cantara, Maria E Cilento, Hongwang Zhang, Ramyani De, Franck Amblard, Philip R Tedbury, Karen A Kirby, Raymond F Schinazi, Stefan G Sarafianos

Journal: SCIENCE ADVANCES

PubMed ID: 40479048

Doi: 10.1126/sciadv.adv8875

Products & Services: PCR Cloning and Subcloning

Designing Sandwich ELISA with Broadly Reactive Anti-Nucleocapsid Monoclonal Antibodies to Detect Bat-Borne Merbecoviruses

Authors: Kong Yen Liew, Yaju Wang, Sneha Sree Mullapudi, Dinah Binte Aziz, Wenjie Fan, Min Luo, Paul Anantharajah Tambyah, Yee-Joo Tan

Journal: Viruses

PubMed ID: 40733504

Doi: 10.3390/v17070886

Products & Services: Gene Synthesis Codon Optimization PCR Cloning and Subcloning

UniClo: scarless hierarchical DNA assembly without sequence constraint

Authors: Carol N Flores-Fernández , Da Lin , Katherine Robins , Chris A O'Callaghan

Journal: Nucleic Acids Research

PubMed ID: 40548934

Doi: 10.1093/nar/gkaf548

Products & Services: PCR Cloning and Subcloning

Synthesis of an E2-Ub-nucleosome conjugate to capture the E3 ligase PHF7-catalyzed H3K14 ubiquitination intermediate

Authors: Shixian Tao, Wei He, Chuntong Li, Jiawei Liang, Zebin Tong, Zhiheng Deng, Liying Zhang, Huasong Ai, Lu-Jun Liang, Lei Liu

Journal: Science China-Chemistry

Doi: 10.1007/s11426-025-2697-6

Products & Services: PCR Cloning and Subcloning