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Protein delivery to the eye: assessing therapeutic potential across inner and outer retina

Authors: Giuditta Dal Cortivo, Carmen Longo, Brigitte Müller, Anna Avesani, Raffaella Pacchiana, Maria Weller, Valerio Marino, Lyubomyr Lytvynchuk, Knut Stieger, Daniele Dell'Orco

Journal: International journal of pharmaceutics

PubMed ID: 41500346

Doi: doi.org/10.1016/j.ijpharm.2026.126568

Products & Services: PCR Cloning and Subcloning

Adenine Base Editing Potently Suppresses Hepatitis B Surface Antigen Expression and Inhibits Hepatitis D Virus Release

Authors: Anuj Kumar, Emmanuel Combe, Elena M Smekalova, Selam Dejene, Dominique Leboeuf, Chao-Ying Chen, Léa Mougené, Marine Deleume, Caroline Scholtes, Marie-Laure Plissonnier, Xavier Grand, Maria G Martinez, Giuseppe Ciaramella, Francine Gregoire, Michael S Packer, Barbara Testoni, Fabien Zoulim

Journal: bioRvix

PubMed ID: 41676540

Doi: 10.64898/2026.02.06.704371

Products & Services: PCR Cloning and Subcloning

A tripartite AAV System with Engineered Lox Sites Enables Efficient Delivery of the EYS Gene for Retinal Gene Therapy

Authors: Kun-Do Rhee, Poppy Datta, Clairissa Baccam, Seongjin Seo

Journal: Human gene therapy

PubMed ID: 41714294

Doi: 10.11710430342261426597

Products & Services: PCR Cloning and Subcloning Custom Vector Construction

Antibody-induced internalization and degradation of PLA2R amplifies CD4+ T cell activation

Authors: Yuning Liu, Yinyin Li, Hui Zhou, Jieli Yu, Pei Deng, Weiwei Xu, Bingqian Pan, Lei Zhang, Hong Zhou, Jing Zhang, Xiaohan Liu, Min Shi, Xianchi Dong, Bei Tong, Enguang Bi, Nannan Guo, Yu Hu

Journal: Theranostics

PubMed ID: 41328348

Doi: 10.7150/thno.123035

Products & Services: Gene Synthesis PCR Cloning and Subcloning

Bringing the ends together: cryo-EM structures of mycobacterial Ku in complex with DNA define its role in NHEJ synapsis

Authors: Joydeep Baral, Ching-Seng Ang, Paul James McMillan, Kalyan Shobhana, Ayushi Saini, Elizabeth Hinde, Amit Kumar Das, Isabelle Rouiller

Journal: Nucleic Acids Research

PubMed ID: 41521670

Doi: 10.1093/nar/gkaf1418

Products & Services: PCR Cloning and Subcloning

Actomyosin-dependent assembly of the mechanosensitive machinery from adherens junctions triggers actin polymerization and organization

Authors: Aurélie Favarin, Rayan Said, Hong Wang, Emilie Zeine, Amaury Pierrard, Julien Pernier, Hemalatha Narassimprakash, Stéphane Roméro, Alexis M Gautreau, René-Marc Mège, Christophe Le Clainche

Journal: SCIENCE ADVANCES

PubMed ID: 41477870

Doi: 10.1126/sciadv.ady4863

Products & Services: PCR Cloning and Subcloning

A Multimodal Ensemble Framework for Optimal Mutant Prediction and Computational Enzyme Engineering

Authors: Ding Luo, Huining Ji, Baodong Hu, Jinxing Cai, Kaiqi Wen, Xiaoyang Qu, Mingfeng Cao, Xinrui Zhao, Binju Wang

Journal: ANGEWANDTE CHEMIE

PubMed ID: 41410226

Doi: 10.1002/anie.202521396

Products & Services: Gene Synthesis PCR Cloning and Subcloning

Acyl-CoA-binding protein AcbdA is required for peroxisome hitchhiking on early endosomes in Aspergillus nidulans

Authors: Bellana E Driscoll, Madison B Fountain, Isabella N Gates, Reihane Abdollahi, Allison M Langley, Matthew B Owens, Jenna R Christensen, John Salogiannis

Journal: Molecular biology of the cell

PubMed ID: 40901736

Doi: 10.1091/mbc.e25-04-0186

Products & Services: Gene Synthesis PCR Cloning and Subcloning

Engineering Multicellular Inter-communication Systems Using a Synthetic Homodimer-inducible Kinase Receptor

Authors: Quan Zhang, Miao Zhang, Yao Zhang, Fenglin Wang, Jian-Hui Jiang

Journal: Angewandte Chemie (International ed. in English)

PubMed ID: 41267507

Doi: 10.1002/anie.202513254

Products & Services: PCR Cloning and Subcloning DNA Sequencing

A genome-wide CRISPR screen in Anopheles mosquito cells identifies fitness and immune cell function-related genes

Authors: Enzo Mameli, George-Rafael Samantsidis, Raghuvir Viswanatha, Hyeogsun Kwon, David R Hall, Matthew Butnaru, Yanhui Hu, Stephanie E Mohr, Norbert Perrimon, Ryan C Smith

Journal: Nature Communications

PubMed ID: 41285753

Doi: 10.1038/s41467-025-65304-y.

Products & Services: PCR Cloning and Subcloning