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Human-specific morphoregulatory signatures in basal radial glia characterise neocortex evolution

Authors: Theresa M Schütze, Annika Kolodziejczyk, Nora Ditzer, Silvia Vangelisti, Emanuele Capra, Jeong-Eun Lee, Ilaria Chiaradia, Vida Kufrin, Seiya Yamada, Jula Peters, Maximilian Krause, Christina Eugster Oegema, Razvan P Derihaci, Cahit Birdir, Takashi Namba, Alexander A Wurm, Ulrich Martin, Pauline Wimberger, Katherine R Long, Madeline A Lancaster, Nereo Kalebic, Boyan Bonev, Mareike Albert

Journal: Nature Communications

PubMed ID: 42855494

Doi: 10.1038/s41467-026-78474-0

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Gliadin-specific CD4+ T cells exhibit functional diversity independent of TCR usage or epitope specificity

Authors: Claerwen M Jones, Jia Jia Lim, Stefan A Schattgen, Tiing Jen Loh, Hien Thy Dao, Mai T Tran, Angela Nguyen, Pirooz Zareie, Nathan J Felix, Paul G Thomas, Melinda Y Hardy, Jason A Tye-Din, Hugh H Reid, Jamie Rossjohn, Nicole L La Gruta

Journal: Science advences

PubMed ID: 42826196

Doi: 10.1126/sciadv.aei3175.

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SMARCA5 facilitates cohesin localization at R-loops to prevent transcription-replication collisions

Authors: Boya Gao, Elizabeth M Irvin, Fengqi Zhang, Parminder Kaur, Ruoxi W Wang, Xiaofeng A Su, Zhubing Shi, Hong Wang, Li Lan

Journal: Cell death and differentiation

PubMed ID: 42946759

Doi: 10.1038/s41418-026-01888-2

Products & Services: PCR Cloning and Subcloning

Neurabin I haploinsufficiency disrupts ion channel regulation and synaptic maturation in human cortical neurons in neurodevelopmental disorders

Authors: Binte Zehra, Nesrin Mohamed, Richa Tambi, Muhammad Faizan, Dharana Satsangi, Alexander D Giddey, Gilles Bru-Mercier, Ahmad Farhat, Nesreen K Al-Jezawi, Muhammad Kumail, Nasna Nassir, Bipin Balan, Noor Kosaji, Mariam Eldesouky, Talal Al Yazeedi, Shuhd BinEshaq, Suhana Shiyas, Nidhina Vinod, Saif S Alqassim, Awab Ahmed, Mohammad Amiruddin Hashmi, Nelson C Soares, Marc Woodbury-Smith, Stefan S Du Plessis, Dimitri J Stavropoulos, Stephen W Scherer, Alawi Alsheikh-Ali, Reem Khalil, Mauro Pessia, Maria Cristina D'Adamo, Bakhrom K Berdiev, Mohammed Uddin

Journal: Molecular Psychiatry

PubMed ID: 42603820

Doi: 10.1038/s41380-026-03818-7

Products & Services: PCR Cloning and Subcloning

RNA synthesis and substrate analog inhibition in the CCHFV polymerase

Authors: Hengxia Jia, Bo Tang, Shunli Liu, Xin Wen, Fan Wu, Xiao Hu, Hu Zhou, Tingting Chong, Lincan Lv, Qiaojie Liu, Guibo Rao, Mingyu Wei, Xuping Jing, Sheng Cao, Fei Deng, Zhihong Hu, Bo Shu, Rui Gong, Jiqin Wu, Manli Wang, Peng Gong

Journal: Nature

Doi: 10.1038/s41586-026-10913-w

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Revisiting the antizyme 1 - ODC interaction reveals low-nanomolar affinity

Authors: Grzegorz P Bereta, Elżbieta Wątor-Wilk, Paweł Kochanowski, Jakub Nowak, Tomasz Kantyka, Przemysław Grudnik

Journal: Amino Acids

PubMed ID: 41989609

Doi: 10.1007/s00726-026-03519-z

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Adenine Base Editing Potently Suppresses Hepatitis B Surface Antigen Expression and Inhibits Hepatitis D Virus Release

Authors: Anuj Kumar, Emmanuel Combe, Elena M Smekalova, Selam Dejene, Dominique Leboeuf, Chao-Ying Chen, Léa Mougené, Marine Deleume, Caroline Scholtes, Marie-Laure Plissonnier, Xavier Grand, Maria G Martinez, Giuseppe Ciaramella, Francine Gregoire, Michael S Packer, Barbara Testoni, Fabien Zoulim

Journal: bioRvix

PubMed ID: 41676540

Doi: 10.64898/2026.02.06.704371

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Protein delivery to the eye: assessing therapeutic potential across inner and outer retina

Authors: Giuditta Dal Cortivo, Carmen Longo, Brigitte Müller, Anna Avesani, Raffaella Pacchiana, Maria Weller, Valerio Marino, Lyubomyr Lytvynchuk, Knut Stieger, Daniele Dell'Orco

Journal: International journal of pharmaceutics

PubMed ID: 41500346

Doi: doi.org/10.1016/j.ijpharm.2026.126568

Products & Services: PCR Cloning and Subcloning

A tripartite AAV System with Engineered Lox Sites Enables Efficient Delivery of the EYS Gene for Retinal Gene Therapy

Authors: Kun-Do Rhee, Poppy Datta, Clairissa Baccam, Seongjin Seo

Journal: Human gene therapy

PubMed ID: 41714294

Doi: 10.11710430342261426597

Products & Services: PCR Cloning and Subcloning Custom Vector Construction

Actomyosin-dependent assembly of the mechanosensitive machinery from adherens junctions triggers actin polymerization and organization

Authors: Aurélie Favarin, Rayan Said, Hong Wang, Emilie Zeine, Amaury Pierrard, Julien Pernier, Hemalatha Narassimprakash, Stéphane Roméro, Alexis M Gautreau, René-Marc Mège, Christophe Le Clainche

Journal: SCIENCE ADVANCES

PubMed ID: 41477870

Doi: 10.1126/sciadv.ady4863

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