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Direct repeat region 3’ end modifications regulate Cas12a activity and expand its applications

Authors: Wei Zhang , Yinyin Zhong , Jiaqi Wang , Guangrong Zou , Qiaozhen Chen , Chaoxing Liu

Journal: Nucleic Acids Res

PubMed ID: 39883010

Doi: 10.1093/nar/gkaf040

Products & Services: PCR Cloning and Subcloning

Multiplexed Assays of Variant Effect and Automated Patch Clamping Improve KCNH2-LQTS Variant Classification and Cardiac Event Risk Stratification

Authors: Matthew J O'Neill, Chai-Ann Ng, Takanori Aizawa, Luca Sala, Sahej Bains, Annika Winbo, Rizwan Ullah, Qianyi Shen, Chek-Ying Tan, Krystian Kozek, Loren R Vanags, Devyn W Mitchell, Alex Shen, Yuko Wada, Asami Kashiwa, Lia Crotti, Federica Dagradi, Giulia Musu, Carla Spazzolini, Raquel Neves, J Martijn Bos, John R Giudicessi, Xavier Bledsoe, Eric R Gamazon, Megan C Lancaster, Andrew M Glazer, Bjorn C Knollmann, Dan M Roden, Jochen Weile, Frederick Roth, Joe-Elie Salem, Nikki Earle, Rachael Stiles, Taylor Agee, Christopher N Johnson, Minoru Horie, Jonathan R Skinner, Michael J Ackerman, Peter J Schwartz, Seiko Ohno, Jamie I Vandenberg, Brett M Kroncke

Journal: Circulation

PubMed ID: 39315434

Doi: 10.1161/CIRCULATIONAHA.124.069828

Products & Services: PCR Cloning and Subcloning

Supramolecular complexes of GCAP1: implications for inherited retinal dystrophies

Authors: Amedeo Biasi, Valerio Marino, Giuditta Dal Cortivo, Daniele Dell'Orco

Journal: International Journal of Biological Macromolecules

PubMed ID: 39187109

Doi: doi.org/10.1016/j.ijbiomac.2024.135068

Products & Services: Peptide Synthesis PCR Cloning and Subcloning Mutagenesis Services

Two riboswitch classes that share a common ligand-binding fold show major differences in the ability to accommodate mutations

Authors: Yoshita Srivastava , Olayinka Akinyemi , Tiana C Rohe , Elizabeth M Pritchett , Cameron D Baker , Akshara Sharma , Jermaine L Jenkins , David H Mathews , Joseph E Wedekind

Journal: Nucleic Acids Research

PubMed ID: 39413212

Doi: 10.1093/nar/gkae886

Products & Services: CRISPR KI Templates PCR Cloning and Subcloning Mutagenesis Services

Reduced Cross-Protective Potential of Omicron Compared to Ancestral SARS-CoV-2 Spike Vaccines Against Potentially Zoonotic Coronaviruses

Authors: Tyler RennerMatthew StuibleBrian CassSylvie PerretJulie GuimondSimon Lord-DufourMichael J. McCluskieYves DurocherBassel Akache

Journal: npj Viruses

Doi: doi.org/10.21203/rs.3.rs-4791122/v1

Products & Services: Gene Synthesis PCR Cloning and Subcloning

Highly sensitive and selective electrochemical biosensor using odorant-binding protein to detect aldehydes

Authors: Cong Peng a b, Yutong Sui a, Chaohua Fang a, Hongxu Sun a, Wenxin Liu a, Xinying Li a, Chen Qu a, Wenhui Li a, Jiemin Liu a c, Chuandong Wu a

Journal: Analytica Chimica Acta

Doi: 10.1016/j.aca.2024.342932

Products & Services: PCR Cloning and Subcloning

Engineering psychrophilic polymerase for nanopore long-read sequencing

Authors: Yaping Sun , Danny Hsu Ko , Jie Gao , Kang Fu , Yuanchen Mao , Yun He , Hui Tian

Journal: Front Bioeng Biotechnol

PubMed ID: 39011153

Doi: 10.3389/fbioe.2024.1406722

Products & Services: PCR Cloning and Subcloning

Population differentiation and dynamics of five pioneer species of Gaultheria from the secondary forests in subtropical China

Authors: Yi-Rong Li, Peter W Fritsch, Gui-Gang Zhao, Xiao-Juan Cheng, Zhao-Li Ding, Lu Lu

Journal: BMC Plant Biol