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Ehrlichia chaffeensis Outer Membrane Protein 1-Specific Human Antibody-Mediated Immunity Is Defined by Intracellular TRIM21-Dependent Innate Immune Activation and Extracellular Neutralization

Authors: Velayutham TS, Kumar S, Zhang X, Kose N, Walker DH, Winslow G, Crowe JE Jr, McBride JW, ,

Journal: Infect Immun

PubMed ID: 31548319

Doi: 10.1128/IAI.00383-19

Products & Services: Peptide Synthesis

Loss of MCU prevents mitochondrial fusion in G1-S phase and blocks cell cycle progression and proliferation

Authors: Koval OM, Nguyen EK, Santhana V, Fidler TP, Sebag SC, Rasmussen TP, Mittauer DJ, Strack S, Goswami PC, Abel ED, Grumbach IM, ,

Journal: Sci Signal

PubMed ID: 31040260

Doi: 10.1126/scisignal.aav1439

Products & Services: Peptide Synthesis

CRISPR-Cas3 induces broad and unidirectional genome editing in human cells

Authors: Morisaka H, Yoshimi K, , Okuzaki Y, Gee P, Kunihiro Y, Sonpho E, Xu H, Sasakawa N, Naito Y, Nakada S0, Yamamoto T, Sano S, Hotta A, Takeda J, Mashimo T,

Journal: Nat Commun

PubMed ID: 31811138

Doi: 10.1038/s41467-019-13226-x

Products & Services: Peptide Synthesis

Cross-Reactive Donor-Specific CD8+ Tregs Efficiently Prevent Transplant Rejection

Authors: Picarda E, Bézie S, Usero L, Ossart J, Besnard M, Halim H, Echasserieau K, Usal C, Rossjohn J, Bernardeau K, Gras S, Guillonneau C

Journal: Cell Rep

PubMed ID: 31875536

Doi: 10.1016/j.celrep.2019.11.106

Products & Services: Peptide Synthesis

Revealing the interaction mode of the highly flexible Sorghum bicolor Hsp70/Hsp90 organizing protein (Hop): A conserved carboxylate clamp confers high affinity binding to Hsp90.

Authors: Adão R, Zanphorlin LM, Lima TB, Sriranganadane D, Dahlström KM, Pinheiro GMS, Gozzo FC, Barbosa LRS, Ramos CHI.