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The morphogen Sonic hedgehog inhibits its receptor Patched by a pincer grasp mechanism.

Authors: Rudolf AF, Kinnebrew M, Kowatsch C, Ansell TB, El Omari K, Bishop B, Pardon E,, Schwab RA, Malinauskas T, Qian M, Duman R, Covey DF, Steyaert J,, Wagner A, Sansom MSP, Rohatgi R, Siebold C.

Journal: Nat Chem Biol

PubMed ID: 31548691

Doi: 10.1038/s41589-019-0370-y

Products & Services: Peptide Synthesis

Skeletal Stem Cell-Schwann Cell Circuitry in Mandibular Repair.

Authors: Jones RE, Salhotra A, Robertson KS, Ransom RC, Foster DS, Shah HN, Quarto N, Wan DC, Longaker MT.

Journal: Cell Rep

PubMed ID: 31509739

Doi: 10.1016/j.celrep.2019.08.021

Products & Services: Peptide Synthesis

High-Throughput Stability Screening of Neoantigen/HLA Complexes Improves Immunogenicity Predictions.

Authors: Blaha DT#, Anderson SD#, Yoakum DM, Hager MV, Zha Y, Gajewski TF, Kranz DM.

Journal: Cancer Immunol Res

PubMed ID: 30425106

Doi: 10.1158/2326-6066.CIR-18-0395

Products & Services: Peptide Synthesis

Unlocking NuriPep 1653 From Common Pea Protein: A Potent Antimicrobial Peptide to Tackle a Pan-Drug Resistant Acinetobacter baumannii.

Authors: Mohan NM,, Zorgani A, Jalowicki G, Kerr A, Khaldi N, Martins M.

Journal: Front Microbiol

PubMed ID: 31620099

Doi: 10.3389/fmicb.2019.02086

Products & Services: Peptide Synthesis

The dense granule protein 8 (GRA8) is a component of the sub-pellicular cytoskeleton in Toxoplasma gondii.

Authors: Díaz-Martín RD, Mercier C, Gómez de León CT, González RM, Pozos SG, Ríos-Castro E, García RA, Fox BA, Bzik DJ, Flores RM.

Journal: Parasitol Res

PubMed ID: 30949853

Products & Services: Peptide Synthesis

Nanodomain Clustering of the Plant Protein Remorin by Solid-State NMR.

Authors: Legrand A,, Martinez D, Grélard A, Berbon M, Morvan E, Tawani A, Loquet A, Mongrand S, Habenstein B.

Journal: Front Mol Biosci

PubMed ID: 31681795

Doi: 10.3389/fmolb.2019.00107

Products & Services: Peptide Synthesis

Protective Effect of PBCA Nanoparticles Loaded with Thymulin Against the Relapsing-Remitting Form of Experimental Autoimmune Encephalomyelitis in Mice.

Authors: Lunin SM, Khrenov MO, Glushkova OV, Parfenyuk SB, Novoselova TV, Novoselova EG.

Journal: Int J Mol Sci

PubMed ID: 31671728

Products & Services: Peptide Synthesis

Three Capsular Polysaccharide Synthesis-Related Glucosyltransferases, GT-1, GT-2 and WcaJ, Are Associated With Virulence and Phage Sensitivity of Klebsiella pneumoniae.

Authors: Cai R, Wang G, Le S, Wu M, Cheng M, Guo Z, Ji Y, Xi H, Zhao C, Wang X, Xue Y, Wang Z, Zhang H, Fu Y, Sun C, Feng X, Lei L, Yang Y, Ur Rahman S, Liu X, Han W,, Gu J.

Journal: Front Microbiol

PubMed ID: 31191500

Doi: 10.3389/fmicb.2019.01189

Products & Services: Peptide Synthesis

Spatial regulation of GPR64/ADGRG2 signaling by β-arrestins and GPCR kinases.

Authors: Azimzadeh P, Talamantez-Lyburn SC, Chang KT, Inoue A, Balenga N,.

Journal: Ann N Y Acad Sci

PubMed ID: 31502283

Doi: 10.1111/nyas.14227

Products & Services: Peptide Synthesis

Intratumoral immunotherapy with TLR7/8 agonist MEDI9197 modulates the tumor microenvironment leading to enhanced activity when combined with other immunotherapies.

Authors: Mullins SR, Vasilakos JP, Deschler K, Grigsby I, Gillis P, John J, Elder MJ, Swales J, Timosenko E, Cooper Z, Dovedi SJ, Leishman AJ, Luheshi N, Elvecrog J, Tilahun A, Goodwin R, Herbst R, Tomai MA, Wilkinson RW.

Journal: J Immunother Cancer

PubMed ID: 31511088

Doi: 10.1186/s40425-019-0724-8

Products & Services: Peptide Synthesis