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A biomimetic nanodisc system selectively activates type I interferons by nonclassical STING pathway for cancer immunotherapy

Authors: Qianwen Mu, Haolan Deng, Shuo Li, Xiaoyu An, Xuan Liu, Yue Xi, Hao Liang, Di Sun, Xiaojun Wang, Xue Liu, Gang Liu, Chao Liu

Journal: Nature Communications

PubMed ID: 41917023

Doi: 10.1038/s41467-026-71363-6

Products & Services: Peptide Synthesis Protein Electrophoresis and Western

CRISPR/Cas9-Based Vanadium MXene-Free Radical Spatiotemporally Controlled Nanoreactor for Photothermal-Induced Multi-Effect Synergistic Antitumor Therapy

Authors: Zi-Jian Huang, Feng-Ming Li, Yi-Fan Tu, Ke-Ke Feng, Cheng-Lei Li, Shi-Cheng Tian, Yong-Shan Hu, Jing-Wei Shao, Zhen-Hua Liu

Journal: Advanced Science

PubMed ID: 41818620

Doi: 10.1002/advs.202522535

Products & Services: Peptide Synthesis

mRNA lipid-nanoparticle-mediated mitochondrial apoptosis augments adoptive T cell immunotherapy

Authors: Jiayan Fu, Yaoqi Liu, Zhenyu Zhong, Benyuan Cao, Luna Ran, Zijia Guo, Haiyang Dong, Nengcheng Bao, Rongqing Pan, Jinqiang Wang, Yuanhui Mao, Yongfeng Jin

Journal: Cell Reports Medicine

PubMed ID: 41916290

Doi: 10.1016/j.xcrm.2026.102706

Products & Services: Peptide Synthesis

Elucidating the Molecular Mechanism of 3D1 Antibody Binding to a Swine Enteric Coronavirus Antigen

Authors: Liangminghui Zhang, Ze Liang, Guang Yang, Lei Yan

Journal: Viruses

PubMed ID: 41754551

Doi: 10.3390/v18020208

Products & Services: Peptide Synthesis

Phloretin targeting the 3CLpro Cys144 exhibits broad-spectrum antiviral activity against swine enteric coronavirus

Authors: Jiawei Xiao, Donghua Guo, Xiaoxu Xing, Limin Jiang, Shanshan Qi, Jun Wang, Wenfei Bai, Shiping Yu, Fanbo Shen, Xingyang Guo, Xinglin Wang, Wei Zhou, Hansong Li, Feiyu Zhao, Li Feng, Jialin Zhang, Yaru Xu, Dan Yang, Haixin Liu, Dongbo Sun

Journal: Molecular Therapy

PubMed ID: 41720346

Doi: 10.1016/j.virs.2026.02.011

Products & Services: Peptide Synthesis

Attenuation of Influenza a Virus into Live Vaccines Through C-End Degrons

Authors: Ping Wang, Le Li, Yunfang Chen, Le Tong, Zhen Li, Rong Yu, Quan Shen, Qikai Wang, Jihuan Hou, Qisi Zhang, Xu Si, Ning Wang, Demin Zhou, Wen-Xia Tian, Longlong Si

Journal: Advanced Science

PubMed ID: 41721587

Doi: 10.1002/advs.202509425

Products & Services: Peptide Synthesis

E711-19 placement and orientation dictate CD8+ T cell response in structurally defined spherical nucleic acid vaccines

Authors: Jeongmin Hwang, Tonatiuh A Ocampo, Vinzenz Mayer, Janice Kang, Krishna S Paranandi, Young Jun Kim, Zhenyu Han, John P Cavaliere, Sergej Kudruk, Jochen H Lorch, Chad A Mirkin

Journal: SCIENCE ADVANCES

PubMed ID: 41671353

Doi: 10.1126/sciadv.aec3876

Products & Services: Peptide Synthesis

Rapid discovery of repurposed drugs targeting SARS-CoV-2 spike HR1 by DNA-encoded library screening

Authors: Qingao Xue, Ze Liang, Yi Zhang, Fei Wang, Fulian Wang, Lili Liu, Guang Yang, Lei Yan

Journal: Bioorganic Chemistry

PubMed ID: 41691755

Doi: 10.1016/j.bioorg.2026.109627

Products & Services: Peptide Synthesis

Functional and Mechanistic Investigation of a Distinct DUF6895 Family Epimerase Involved in Lasso Peptide Modification

Authors: Menghan Shi, Yuwei Duan, Shao-Yang Hou, Liangxu Xie, Weifeng Sun, Liubin Feng, Youming Zhang, Xiaoying Bian, and Guannan Zhong

Journal: ACS catalysis

Doi: 10.1021/acscatal.5c08590

Products & Services: Peptide Synthesis

Screening for novel variable domains of the heavy chains of heavy-chain antibodies targeting different epitopes of thrombomodulin and Luminex fluorescence immunoassay for soluble thrombomodulin

Authors: Congcong Jia, Min Zhu, Yuelan He, Meixiang Yu, Xinyi Xia, Weiwei Ji, Xiang Cao, Jianzhong Lu, Hai Zhang

Journal: International Journal of Biological Macromolecules

PubMed ID: 41314569

Doi: 10.1016/j.ijbiomac.2025.149289

Products & Services: Gene Synthesis Peptide Synthesis