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Engineered haptoglobin β fusion protein targets myoglobin and ameliorates rhabdomyolysisassociated acute kidney injury

Authors: Ning Li, Yuru Wang, Lu Han, Ou Qiao, Xinyue Wang, Herui Hao, Xin Chen, Pengtao Wang, Sania Saeed, Jing Wang, Fengjiao Bao, Yingjie Hou, Li Zhang, Xiaohong Duan, Shuquan Rao, Yanhua Gong

Journal: EMBO Molecular Medicine

PubMed ID: 42185634

Doi: 10.1038/s44321-026-00454-0

Products & Services: Synthetic Guide RNA

Radiotherapy synergizes with an inducible AAVbased immunotherapy platform to program local and systemic antitumor immunity

Authors: Sonia Marco, Myriam Fernández, Beatriz Honorato, Nerea Juanarena, Cristina Sainz, Ainhoa Andueza, David J Gould, Seth Anderson, Carlos de Andrea, Paulo Pérez Domínguez, Paolo Wong, Carlos Vásquez, Irene Narinda, Carmen Unzu, Sergio Isola, Beatriz Tavira, Mikel Ariz, Gracián Camps, Miguel F Sanmamed, Julián Pardo, Sara Labiano, Marta M Alonso, Javier Marco-Sanz, Elizabeth Guruceaga, María Collantes, Jon Ander Simón, Iván Peñuelas, Joaquín Fernández-Irigoyen, Enrique Santamaría, Jesús Prieto, Juan Dubrot

Journal: Cancer Cell

PubMed ID: 41875889

Doi: doi.org/10.1016

Products & Services: Gene Synthesis

Stimuli-triggered formation of de novo -designed protein biomaterials

Authors: Nicole E. Gregorio; Zhe Li; Jack W. Hoye; David Baker; Cole A. DeForest

Journal: Cell Biomaterials

PubMed ID: 41909827

Doi: 10.1016/j.celbio.2025.100239

Stimuli-triggered formation of de novo -designed protein biomaterials

Authors: Nicole E. Gregorio; Zhe Li; Jack W. Hoye; David Baker; Cole A. DeForest

Journal: Cell Biomaterials

PubMed ID: 41909827

Doi: 10.1016/j.celbio.2025.100239

Structural basis for the subtype-selective activation of KCa3.1 channels

Authors: Alena Ramanishka, Joshua A. Nasburg, Yang Xu, Xinyi Ma, Reza Mehvar, Meng Cui, Young-Woo Nam, Heike Wulff, Miao Zhang

Journal: Structure

Doi: 10.1016/j.bpj.2025.11.2173

Products & Services: Gene Synthesis

Polypeptides synthesized by common bacteria in the human gut improve rodent metabolism

Authors: Yong Fan; Liwei Lyu; Ruben Vazquez-Uribe; Wanliang Zhang; Mareike Bongers; Andreas Koulouktsis; Mengliu Yang; Vita Sereika-Bejder; Tulika Arora; Evelina Stankevic; Jeremy Armetta; Franziska Zosel; Charlotta D. de la Cour; Lotte Simonsen; Alina Kulakova; Michael Wierer; Pernille Harris; Joachim G de; Peter Rossing; Filip K. Knop; Tune H. Pers; Tue Haldor Hansen; Trine Nielsen; Ling Li; Kristian Str mgaard; Gangyi Yang; Morten Otto Alexander Sommer; Oluf Pedersen

Journal: Nature Microbiology

PubMed ID: 40745048

Doi: 10.1038/s41564-025-02064-x

A nanobody-based proteolysis-targeting chimera offers broad-spectrum protection against diverse influenza virus infections

Authors: Yichao Zhuang, Lei Chen, Chen Qin, Puze Chen, Lulu Feng, Weipeng Lin, Jiaqi Li, Yaping Zhang, Congcong Wang, Jianzhong Shi, Guohua Deng, Xianying Zeng, Pengfei Cui, Yanbing Li, Yongping Jiang, Hualan Chen, Huihui Kong

Journal: Signal transduction and targeted therapy

PubMed ID: 42140901

Doi: 10.1038/s41392-026-02666-9

Products & Services: Protein Electrophoresis and Western

Polypeptides synthesized by common bacteria in the human gut improve rodent metabolism

Journal: Nature Microbiology

PubMed ID: 40745048

Doi: 10.1038/s41564-025-02064-x

Stimuli-triggered formation of de novo -designed protein biomaterials

Authors: Nicole E. Gregorio; Zhe Li; Jack W. Hoye; David Baker; Cole A. DeForest

Journal: Cell Biomaterials

PubMed ID: 41909827