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页码: 3/5144 每页显示数量

Structural basis for E4 enzyme Ufd2-catalyzed K48/K29 branched ubiquitin chains

Authors: Zebin Tong, Xiangwei Wu, Hongyi Cai, Shidian Wu, Tianyi Zhang, Zhiheng Deng, Ziyu Xu, Rujing Yuan, Huasong Ai, Lei Liu, Man Pan

Journal: Nature Chemical Biology

PubMed ID: 40817136

Doi: 10.1038/s41589-025-01985-2

Products & Services: Gene Synthesis

Pyroptosis-responsive microspheres modulate the inflammatory microenvironment to retard osteoporosis in female mice

Authors: Shunyi Lu, Jie Cao, Zhuorun Song, Fei Gong, Peng Yang, Jun Ge, Yunfei He, Zhihui Han, Guanghui Hou, Zimin Zhang, Yuqi Yang, Yun Teng, Zengli Zhang, Jun Zou, Liang Cheng, Huilin Yang

Journal: Nature Communications

PubMed ID: 40885754

Doi: doi.org/10.1038/s41467-025-63456-5

Products & Services: Proteins, Expression, Isolation and Analysis

A Molecular Mechanism for the Reduction of the Cu Site in Lytic Polysaccharide Monooxygenases by Phenol Reductants

Authors: Langxing Liao, Jian Kuang, Peng Wu, Xianhang Sang, Heng Yin, Changlin Ti, Kingwang Zhang, Wei Peng, Lu Yu, Binju Wang

Journal: JACS Au

Doi: 10.1021/jacsau.5c00562

Products & Services: Gene Synthesis

AMPGen: an evolutionary information-reserved and diffusion-driven generative model for de novo design of antimicrobial peptides

Authors: Shuwen Jin, Zihan Zeng, Xiyan Xiong, Baicheng Huang, Li Tang, Hongsheng Wang, Xiao Ma, Xiaochun Tang, Guoqing Shao, Xingxu Huang, Feng Lin

Journal: Communications Biology

PubMed ID: 40447738

Doi: 10.1038/s42003-025-08282-7

Products & Services: Peptide Synthesis

Exomeres From Adventitial Fibroblasts of Spontaneously Hypertensive Rats Promote Vascular Remodelling via Transferring Osteopontin.

Authors: Jing-Xiao Wang, Xiao-Yu Xu, Hong-Ke Dong, Yi-Ming Wang, Min Dai, Bing Zhou, Yue-Hua Li, Guo-Qing Zhu, Xiao-Qing Xiong

Journal: Journal of Extracellular Vesicles

PubMed ID: 40767027

Doi: 10.1002/jev2.70146.

Products & Services: Custom RNAi Services

Lung metastasis and recurrence is mitigated by CARmacrophages, in-situ-generated from mRNA delivered by small extracellular vesicles

Authors: Yuchen Xiao, Tianchuan Zhu, Zhenxing Chen, Xi Huang

Journal: Nature Communications

PubMed ID: 40759657

Doi: 10.1038/s41467-025-62506-2

Products & Services: Custom DNA/RNA Oligos

The Heme Oxygenase-Like Diiron Enzyme HrmI Reveals Altered Regulatory Mechanisms for Dioxygen Activation and Substrate N-Oxygenation

Authors: Sydney S Skirboll, Medha Gangopadhyay, Han N Phan, Joshua Hartsell, Aditi Mudireddy, Dalton Hilovsky, Paul D Swartz, Xiaojing Liu, Yisong Guo, Thomas M Makris

Journal: Journal of the American Chemical Society

PubMed ID: 40774922

Doi: doi.org/10.1021/jacs.5c08814

Products & Services: Gene Synthesis

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery

Authors: Elias Adriaenssens, Stefan Schaar, Annan S I Cook, Jan F M Stuke, Justyna Sawa-Makarska, Thanh Ngoc Nguyen, Xuefeng Ren, Martina Schuschnig, Julia Romanov, Grace Khuu, Louise Uoselis, Michael Lazarou, Gerhard Hummer, James H Hurley, Sascha Martens

Journal: NATURE CELL BIOLOGY

PubMed ID: 40715440

Doi: 10.1038/s41556-025-01712-y

Products & Services: Gene Synthesis

Elevated uric acid induces erectile dysfunction in rats by interacting with MLCK and inhibiting its ubiquitin-mediated degradation

Authors: Gang Shen, Zhenzhen Fang, Fuyan Hong, Mian Wu, Jing Zhang, Jinhong Wang, Chuan Bai, Wencan Chen, Xia Yang, Chunhua Deng, Haibing Chen, Guoquan Gao, Ti Zhou

Journal: Communications Biology

PubMed ID: 40783594

Doi: 10.1038/s42003-025-08607-6.

Products & Services: Proteins, Expression, Isolation and Analysis

Laodelphax striatellus salivary sheath protein Lsactin triggers defense response in plants

Authors: Liangxuan Qi, Jing Li, Han Wang, Jing Li, Xinyang Tan, Zhichang Zhao, Sicong Zhou, Jichao Fang, Rui Ji

Journal: INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

PubMed ID: 40543628

Doi: 10.1016/j.ibmb.2025.104351

Products & Services: Polyclonal Antibody Services

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