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Cholesterol analogs modulate lipid nanoparticle performance for mRNA delivery after lyophilization and enable ocular disease therapy

Authors: Ting Wang, Wanqi Li, Jianyang Chen, Sitian Cheng, Min Gao, Chengyu Jiang, Chengyu Jiang, Bingyi Hu, Tzu-Cheng Sung, Akon Higuchi

Journal: Materials Today Bio

Doi: 10.1016/j.mtbio.2026.103044

Products & Services: Custom mRNA synthesis

Machine Learning-Enhanced Ultrasensitive Immuno-CRISPR Array Facilitates Early Diagnosis of Alzheimer’s Disease by Detecting Multiple Plasma Biomarkers

Authors: Liding Zhang, Changwen Yang, Qian Yao, Xuewei Du, Shuai Ding, Yaoqiang Shi, Can Sheng, Ming Wang, Ying Han, Haiming Luo

Journal: Advanced Science

PubMed ID: 42261770

Doi: 10.1002/advs.75983

Products & Services: Catalog Antibodies

Sustained-Release Ulcer-Protective Microarray Patch With Dihydrocapsaicin for Diabetic Wound Regeneration

Authors: Yuxu Wu, Kan Jiang, Xiao Wen, Chihao Jin, Kai Zhang, Jiakai Zhang, Jiale Jin, Jiaqian Wang, Huiyu Hu, Zonghan Xu, Xianzhu Zhang, Yihe Hu

Journal: Exploration

Doi: 10.1002/exp.20250129

Products & Services: Protein Electrophoresis and Western

Genuine Directed Evolution In Test Tube (GENie)

Authors: Lilin Feng; Maochao Mao; Ulrich Schwaneberg

Journal: biorxiv

PubMed ID: 42146629

Doi: 10.64898/2026.05.04.722721

Polypeptides synthesized by common bacteria in the human gut improve rodent metabolism

Authors: Yong Fan; Liwei Lyu; Ruben Vazquez-Uribe; Wanliang Zhang; Mareike Bongers; Andreas Koulouktsis; Mengliu Yang; Vita Sereika-Bejder; Tulika Arora; Evelina Stankevic; Jeremy Armetta; Franziska Zosel; Charlotta D. de la Cour; Lotte Simonsen; Alina Kulakova; Michael Wierer; Pernille Harris; Joachim G de; Peter Rossing; Filip K. Knop; Tune H. Pers; Tue Haldor Hansen; Trine Nielsen; Ling Li; Kristian Str mgaard; Gangyi Yang; Morten Otto Alexander Sommer; Oluf Pedersen

Journal: Nature Microbiology

PubMed ID: 40745048

Doi: 10.1038/s41564-025-02064-x

Polypeptides synthesized by common bacteria in the human gut improve rodent metabolism

Journal: Nature Microbiology

PubMed ID: 40745048

Doi: 10.1038/s41564-025-02064-x

Stimuli-triggered formation of de novo -designed protein biomaterials

Authors: Nicole E. Gregorio; Zhe Li; Jack W. Hoye; David Baker; Cole A. DeForest

Journal: Cell Biomaterials

PubMed ID: 41909827

Doi: 10.1016/j.celbio.2025.100239

Engineered haptoglobin β fusion protein targets myoglobin and ameliorates rhabdomyolysisassociated acute kidney injury

Authors: Ning Li, Yuru Wang, Lu Han, Ou Qiao, Xinyue Wang, Herui Hao, Xin Chen, Pengtao Wang, Sania Saeed, Jing Wang, Fengjiao Bao, Yingjie Hou, Li Zhang, Xiaohong Duan, Shuquan Rao, Yanhua Gong

Journal: EMBO Molecular Medicine

PubMed ID: 42185634

Doi: 10.1038/s44321-026-00454-0

Products & Services: Synthetic Guide RNA

Chiral Microenvironment Enhanced Bone Regeneration in Infectious Bone Defect Based on Chiral Molybdenum Disulfide Quantum Dots

Authors: Yiling Yang, Jinshan Xia, Yixiao Xing, Fei Yang, Yang Sun, Wanjing Xu, Yu Ma, Jinchen Fan, Guisheng Li, Youcheng Yu

Journal: Advanced Healthcare Materials

PubMed ID: 41858145

Doi: 10.1002/adhm.202505661

Products & Services: Protein Electrophoresis and Western

Radiotherapy synergizes with an inducible AAVbased immunotherapy platform to program local and systemic antitumor immunity

Authors: Sonia Marco, Myriam Fernández, Beatriz Honorato, Nerea Juanarena, Cristina Sainz, Ainhoa Andueza, David J Gould, Seth Anderson, Carlos de Andrea, Paulo Pérez Domínguez, Paolo Wong, Carlos Vásquez, Irene Narinda, Carmen Unzu, Sergio Isola, Beatriz Tavira, Mikel Ariz, Gracián Camps, Miguel F Sanmamed, Julián Pardo, Sara Labiano, Marta M Alonso, Javier Marco-Sanz, Elizabeth Guruceaga, María Collantes, Jon Ander Simón, Iván Peñuelas, Joaquín Fernández-Irigoyen, Enrique Santamaría, Jesús Prieto, Juan Dubrot

Journal: Cancer Cell

PubMed ID: 41875889

Doi: doi.org/10.1016

Products & Services: Gene Synthesis