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32405 条搜索结果 for protein
Human DNA polymerase η is regulated by mutually exclusive mono-ubiquitination and mono-NEDDylation
Authors: Natália C Moreno, Emilie J Korchak, Marcela T Latancia, Dana A D'Orlando, Temidayo Adegbenro, Ryan P Barnes, Irina Bezsonova, Roger Woodgate, Nicholas W Ashton
Journal: Nucleic Acids Research
PubMed ID: 41693564
Doi: 10.1093/nar/gkag098
PolyP inhibits CobB deacetylase triggering a regulatory coupling to prevent DNA replication initiation
Authors: Ewelina Boguszewska, Zuzanna Hirsz, Magdalena Sroka, Katarzyna Bury, Weronika Chmura, Agnieszka Strzałka, Marta Kołodziej, Jolanta Zakrzewska-Czerwińska, Igor Konieczny
Journal: Nucleic Acids Research
PubMed ID: 41728951
Doi: 10.1093/nar/gkag144
Characterization of gRNA-dependent and gRNA-independent off-target binding sites of PspCas13b and RfxCas13d in mammalian cells
Authors: Huanhuan Feng, Zhixue Li, Hongdao Zhang, Yuli Zheng, Beiying Xu, Yao Zhang, Lin Zou, Ligang Wu
Journal: Nucleic Acids Research
PubMed ID: 41728952
Doi: 10.1093/nar/gkag112
Functional characterization of secreted Schistosoma mansoni serpin SmSPI reveals Factor XIIa inhibition as evidenced by biochemical, and human plasma assays and supported by AI-assisted structural modelling
Authors: Lukáš Konečný, Kristýna Peterková, Ingrid Hrachovinová, Alex Loukas, Tomáš Macháček, Jan Dvořák, Lucie Jedličková
Journal: Molecular Therapy
PubMed ID: 41724421
Doi: 10.1016/j.ijpara.2026.104808
Identifying microbial protease allergens through protein language model-guided homology
Authors: Kumar Thurimella, Elena Wu, Chenhao Li, Daniel B Graham, Róisín M Owens, Damian R Plichta, Caroline L Sokol, Ramnik J Xavier, Sergio Bacallado
Journal: Molecular Therapy
PubMed ID: 41722567
Doi: 10.1016/j.cels.2025.101510
Messenger RNA delivery to islet β cells using conjugated lipid nanoparticles
Authors: Jacob R Enriquez, Zhengjie Zhou, Jennifer B Nelson, Fei Huang, Kayla T Figatner, Advaita Chakraborty, Sarida Pratuangtham, Brian Xi, Sarah C May, Matthew V Tirrell, Sarah A Tersey, Yun Fang, Raghavendra G Mirmira
Journal: Molecular Therapy
PubMed ID: 41722565
Doi: 10.1016/j.xcrm.2026.102634
Products & Services: Recombinant Proteins   
Identification of xenobiotics interfering with 5α-reductase (SRD5A2) activity
Authors: Jacek Kędzierski, Rianne E van Diest, Julien A Allard, Andreas M Erharter, Alex Odermatt, Martin Smieko
Journal: Molecular Therapy
PubMed ID: 41722875
Doi: 10.1016/j.toxlet.2026.111859
Products & Services: Custom Vector Construction   
The protein phosphatase 2A-B56α complex regulates N-Myc degradation in neuroblastoma
Authors: Brian D Tran, Irene Peris, Ethan Wurman, Averie Huang, Gabrielle Hodges Onishi, Jiang Hu, Rita A Avelar, Erika A Newman, Analisa DiFeo, Caitlin M O'Connor, Goutham Narla
Journal: Molecular Therapy
PubMed ID: 41707997
Doi: 10.1016/j.jbc.2026.111298
Heterologous vs. homologous vaccine regimens: Sulfated lactosyl archaeol (SLA) archaeosome-adjuvanted SARS-CoV-2 spike protein boost following an mRNA/LNP prime induces robust and balanced immune responses
Authors: Tyler M Renner, Gerard Agbayani, Hiva Azizi, Lise Deschatelets, Renu Dudani, Blair A Harrison, Usha D Hemraz, Roger Koukiekolo, Matthew Stuible, Yves Durocher, Michael J McCluskie, Bassel Akache
Journal: Vaccine
PubMed ID: 41505874
Doi: 10.1016/j.vaccine.2025.128182
Products & Services: Codon Optimization   Gene Synthesis   
Humanization and engineering of protective antibodies targeting severe fever with thrombocytopenia syndrome virus Gn protein
Authors: Xuanxiu Ren, Wei Deng, Feiyang Yu, Wenhua Kuang, Heya Na, Shangyu Yang, Jiawen Sun, Jianlun Xu, Bo Shu, Sheng Cao, Xianliang Ke, Zengqin Deng, Yun-Jia Ning, Haiyan Zhao
Journal: Cell Reports
PubMed ID: 41671090
Doi: 10.1016/j.celrep.2026.116936
Products & Services: Protein and Antibody Isolation