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Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein

Authors: Marie-Lynn Cuypers; Tom Jaspers; Jarne Clerckx; Simon Leekens; Christopher Cawthorne; Guy Bormans; Frederik Cleeren; Nick Geukens; Bart De Strooper; Maarten Dewilde

Journal: Fluids and barriers of the CNS

PubMed ID: 39885527

Doi: 10.1186/s12987-025-00624-1

Products & Services: Proteins, Expression, Isolation and Analysis

Single-cycle parainfluenza virus type 5 vectors for producing recombinant proteins, including a humanized anti-V5 tag antibody

Authors: Richard E Randall , Dan Young , Maria Pisliakova , Jelena Andrejeva , Lynsey West , Luis Rossler , Volker Morath , David Hughes , Steve Goodbourn

Journal: JOURNAL OF GENERAL VIROLOGY

PubMed ID: 39786361

Doi: 10.1099/jgv.0.002061

Products & Services: Gene Synthesis PCR Cloning and Subcloning

Biochemical characterization and discovery of inhibitors for PfSir2A: new tricks for an old enzyme

Authors: Dickson Donu, Emily Boyle, Alyson Curry, Yana Cen

Journal: RSC Chemical biology

PubMed ID: 39897407

Doi: 10.1039/d4cb00206g

Products & Services: Peptide Synthesis

Salivary elicitor disulffde isomerase from Nilaparvata lugens targets host rice UDP-glucose epimerase 2 to induce plant defenses

Authors: Jianmei Fu , Zhichang Zhao , Jichao Fang , Rui Ji

Journal: Plant Stress

Doi: doi.org/10.1016/j.stress.2025.100744

Products & Services: Polyclonal Antibody Services

Energy-guided accumulated mutation strategy achieves a highly efficient polyethylene terephthalate-degrading enzyme

Authors: Zhi Wang, Jiaxing Zhang, Shengping You, Rongxin Su, Wei Qi

Journal: Biochemical Engineering Journal

Doi: 10.1016/j.bej.2025.109708

Products & Services: Proteins, Expression, Isolation and Analysis

Discovering CRISPR-Cas system with self-processing pre-crRNA capability by foundation models

Authors: Wenhui Li, Xianyue Jiang, Wuke Wang, Liya Hou, Runze Cai, Yongqian Li, Qiuxi Gu, Qinchang Chen, Peixiang Ma, Jin Tang, Menghao Guo, Guohui Chuai, Xingxu Huang, Jun Zhang, Qi Liu

Journal: Nature Communications

PubMed ID: 39789054

Products & Services: Synthetic sgRNA and crRNA Service

A nanobody-enzyme fusion protein targeting PD-L1 and sialic acid exerts anti-tumor effects by C-type lectin pathway-mediated tumor associated macrophages repolarizing

Authors: Yongliang Tong , Runqiu Chen , Xinrong Lu , Cuiying Chen , Guiqin Sun , Xiaolu Yu , Shaoxian Lyu , Meiqing Feng , Yiru Long , Likun Gong , Li Chen

Journal: Int J Biol Macromol

PubMed ID: 39824395

Doi: 10.1016/j.ijbiomac.2025.139953

Products & Services: Gene Synthesis

Developing orthogonal fluorescent RNAs for photoactive dual-color imaging of RNAs in live cells

Authors: Peng Yin , Chunzheng Huang , Li Zhang , Zhenzhen Li , Caijun Zhong , Shi Kuang , Chunyang Lei , Yan Huang , Zhou Nie

Journal: Angew Chem Int Ed Engl

PubMed ID: 39801450

Doi: 10.1002/anie.202424060

Products & Services: Plasmid DNA Preparation

Manganese Galvanic Cells Intervene in Tumor Metabolism to Reinforce cGAS-STING Activation for Bidirectional Synergistic Hydrogen-Immunotherapy

Authors: Nailin Yang , Shumin Sun , Jiachen Xu , Fei Gong, Huali Lei , Yu Hao , Zifan Pei , Chenya Wang , Qiao Yu , Jihu Nie , Nan Jiang , Caifang Ni , Liang Cheng

Journal: Adv Mater

PubMed ID: 10.1002/adma.202414929

Doi: 10.1002/adma.202414929

Products & Services: Proteins, Expression, Isolation and Analysis

Computational design, expression, and characterization of a Plasmodium falciparum multi-epitope, multi-stage vaccine candidate (PfCTMAG)

Authors: Joan A Chick, Nadege N Abongdia, Robert A Shey, Tobias O Apinjoh

Journal: Heliyon

PubMed ID: 39906795

Doi: 10.1016/j.heliyon.2025.e42014

Products & Services: Bacterial Expression

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