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SnRK2.5-mediated phosphorylation of PIN2 links osmotic stress signaling with auxin dependent root adaptive growth in Arabidopsis

Authors: Shujuan Zhang, Zilong Cui, Yu Gao, Qi Liao, Wenyan Li, Siqi Yuan, Zhuomeng Li, Xinwen Zhang, Kai Ding, Wenjing Zhang, Like Shen, Jörg Kudla, Wenhua Zhang, Jing Zhang, Qun Zhang

Journal: Molecular Plant

PubMed ID: 41353562

Doi: 10.1016/j.molp.2025.12.002

Products & Services: Protein and Antibody Isolation Catalog Antibodies

Discovery of novel pyrrolidine-2,5-dione scaffold PICK1 PDZ inhibitors as anti-ischemic stroke agents

Authors: Yichen Jiang, Qi Liu, Ting Zhu, Ruiguo Liang, Yujiao Qin, Xiya Guo, Jiacheng Wang, Ping Li, Jie Zhou, Han Ju, Mingxin Dong

Journal: European Journal of Medicinal Chemistry

PubMed ID: 41386205

Doi: 10.1016/j.ejmech.2025.118410

Products & Services: Plasmid DNA Preparation

The extracellular domain of mGluR6 regulates targeting to the conventional secretion pathway

Authors: Andrew P Rideout, Omar W Abuelatta, Melina A Agosto

Journal: Molecular and cellular neurosciences

PubMed ID: 41448371

Doi: 10.1016/j.mcn.2025.104068

Products & Services: Protein and Antibody Isolation

A broadly neutralizing antibody confers cross-genus protection against alphaherpesviruses by inhibiting gB-mediated membrane fusion

Authors: Guosong Wang, Yu Li, Chongxin Wu, Tian Chen, Mengxuan Gui, Yue Zeng, Hui Sun, Kaiyun Chen, Xiangfeng Xi, Yanbo Yang, Yuchen Jiang, Yanan Jiang, Liqin Liu, Chengyu Yang, Jiarui Xin, Caihong Liu, Yiyi Li, Ningning Huo, Yang Huang, Lina Lin, Hai Yu, Chenghao Huang, Quan Yuan, Shaowei Li, Kegong Tian, Qingbing Zheng, Ningshao Xia, Yixin Chen

Journal: Nature Communications

PubMed ID: 41402251

Doi: 10.1038/s41467-025-66099-8

Products & Services: Antibody Modification and Purification Services

Human Substance P Interactions with G Protein-Coupled Receptor NK1R Observed by NMR in Solution

Authors: Haoyi Ge, Lingyun Yang, Changran Chen, Yuxin Xu, Dongsheng Liu, Kurt Wüthrich

Journal: Journal of the American Chemical Society

PubMed ID: 41264783

Doi: doi.org/10.1021/jacs.5c12553

Products & Services: Peptide Synthesis

Far-red light orchestrates antiviral defense in plants

Authors: Qian Gong, Linfang He, Fan Huang, Yunjing Wang, Jinchuan Xie, Yiguo Hong, Yule Liu

Journal: SCIENCE ADVANCES

PubMed ID: 41259508

Doi: 10.1126/sciadv.adz7663

Products & Services: Protein and Antibody Isolation

A yeast surface display platform for characterizing CAR T cell responses to cancer antigens

Authors: Marcus Deichmann, Giovanni Schiesaro, Keerthana Ramanathan, Katrine Zeeberg, Nanna M T Koefoed, Maria Ormhøj, Rasmus U W Friis, Ryan T Gill, Sine R Hadrup, Emil D Jensen, Michael K Jensen

Journal: Nature Communications

PubMed ID: 41271729

Doi: 10.1038/s41467-025-65236-7.

Products & Services: Peptide Synthesis

Modeling and addressing on-target/off-tumor toxicity of claudin 18.2 targeted immunotherapies

Authors: Elizabeth J Carstens, Kazuki Takahashi, Naoya Sakamoto, Martina De Vizio, Micaela Morgado, Shahryar Khoshtinat Nikkhoi, Abhishek Mangipudi, Canh Hiep Nguyen, Tate Weltzin, Izuma Nakayama, Qiang Lv, Jue Zeng, Cui Nie, Changjing Deng, Xiaoxiao Wang, Lile Liu, Samuel J Klempner, Anusuya Ramasubramanian, Jonathan A Nowak, Andrew J Aguirre, Kohei Shitara, Eric L Smith

Journal: Nature Communications

PubMed ID: 41176582

Doi: 10.1038/s41467-025-65148-6.

Products & Services: Recombinant Proteins

Pmt4 recognizes two separate acceptor sites to O-mannosylate in the S/T-rich regions of substrate proteins

Authors: Minge Du, Zuanning Yuan, Amanda Kovach, Meinan Lyu, Huilin Li

Journal: Nature Communications

PubMed ID: 41188226

Doi: 10.1038/s41467-025-64729-9.

Products & Services: Protein and Antibody Isolation

Double-stranded DNA deaminase DddAE1347A can increase the efficiency and targeting range of cytidine base editors

Authors: Yuqiang Qian, Fengjiao Hui, Wenchao Niu, Di Wang, Yang Hao, Qingying Meng, Siyu Ren, Deqiang Kong, Heng Gong, Jiayu Wu, Kexin Chen, Muna Alariqi, Junping Gao, Zhanjun Li, Shuangxia Jin

Journal: Genome Biology

PubMed ID: 41250247

Doi: 10.1186/s13059-025-03849-3

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

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