GenScript - Make Research Easy - The leader in molecular cloning and gene synthesis, peptide synthesis,protein and antibody engineering.

Glutathionylated DNA adducts accumulate in mitochondrial DNA and are regulated by AP endonuclease 1 and tyrosyl-DNA phosphodiesterase 1

Authors: Yu Hsuan Chen, Martin Esparza Sanchez, Ta I Hung, Jin Tang, Wenyan Xu, Jiekai Yin, Yinsheng Wang, Chia-En A Chang, Huimin Zhang, Junjie Chen, Linlin Zhao

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 41259143

Doi: doi.org/10.1073/pnas.2509312122

Products & Services: Catalog Antibodies

Engineering Multicellular Inter-communication Systems Using a Synthetic Homodimer-inducible Kinase Receptor

Authors: Quan Zhang, Miao Zhang, Yao Zhang, Fenglin Wang, Jian-Hui Jiang

Journal: Angewandte Chemie (International ed. in English)

PubMed ID: 41267507

Doi: 10.1002/anie.202513254

Products & Services: PCR Cloning and Subcloning DNA Sequencing

SLC7A11-independent disulfidptosis induced by a two-pronged delivery strategy for bladder cancer chemotherapy and cisplatin-resistance reverse

Authors: Bin Zheng, Facai Zhang, Heng Wang, Wenyan Zuo, Dingyi Liu, Zhihan Wu, Zhenghong Liu, Haichang Li, Yang Liu, Yixuan Mou, Xiaowen Qin, Dahong Zhang, Pu Zhang, Qi Zhang

Journal: Materials today. Bio

PubMed ID: 41322137

Doi: 10.1016/j.mtbio.2025.102547

Products & Services: Protein and Antibody Isolation

Unveiling conformation-selective regulation of the norepinephrine transporter

Authors: Heng Zhang, Tianwei Zhang, Dingyan Wang, Antao Dai, Jianhang Mao, Qihui Chen, Tianyuan Du, Xue Lu, Yongxin Hao, Chao Zhang, Yu-Ling Yin, Wen Hu, Benxun Pan, Sanshan Jin, Mengting Jiang, Yuan Si, Qingning Yuan, Ming-Wei Wang, Mingyue Zheng, Zhen Wang, Dehua Yang, H Eric Xu, Yi Jiang

Journal: Cell

PubMed ID: 41138730

Doi: 10.1016/j.cell.2025.10.002

Products & Services: Protein and Antibody Isolation

PROTAC repurposing uncovers a noncanonical binding surface that mediates chemical degradation of nuclear receptors

Authors: Andrew D Huber, Wenwei Lin, Young-Hwan Jung, Shyaron Poudel, Guangwei Yang, Jing Wu, Annalise G Carrigan, Vishwajeeth Pagala, Wei Wang, Yingxue Fu, Zuo-Fei Yuan, Stephanie D Byrum, Ka Yang, Rebecca R Florke Gee, Elizabeth D Arnold, Allister J Loughran, Jingheng Wang, Shondra M Pruett-Miller, Junmin Peng, Taosheng Chen

Journal: Nature Communications

PubMed ID: 41198675

Doi: 10.1038/s41467-025-64773-5.

Products & Services: Bacterial Expression

A fungal pathogen manipulates phytocytokine signaling for plant infection

Authors: Chenlei Hua, Lisha Zhang, Annick Stintzi, Andreas Schaller, Hui-Shan Guo, Thorsten Nürnberger

Journal: Nature Communications

PubMed ID: 41238555

Doi: 10.1038/s41467-025-65934-2.

Products & Services: Peptide Synthesis

Spike conformational and glycan heterogeneity associated with furin cleavage causes incomplete neutralization of SARS-CoV-2

Authors: Sahil Kumar, Rathina Delipan, Chanchal Sharma, Jyoti Jadoun, Kawkab Kanjo, Randhir Singh, Raju Rajmani, Suprit Deshpande, Rajesh Pandey, Krishan G Thakur, Jayanta Bhattacharya, Rogier W Sanders, Marit J van Gils, Raghavan Varadarajan, Rajesh P Ringe

Journal: Nature Communications

PubMed ID: 41257850

Doi: 10.1038/s41467-025-65099-y.

FUS nanoclusters are a distinct state within the dilute phase

Authors: Yingda Ge, Tapas Paul, Margarita Gordiychuk, Nilimesh Das, Yaojun Zhang, Sua Myong

Journal: Nature Communications

PubMed ID: 41224766

Doi: 10.1038/s41467-025-64909-7.

TNC-targeted CAR-macrophage therapy alleviates liver fibrosis in mice

Authors: Kai-Zhao Chen, Zi-Yang Lin, Long-Jun Chen, You-Xi Zhou, Wei Zhang, Hao-Yang Wan, Yong-Kun Huo, Qi Fu, Zi-Qing Gao, Hong-Wei Cheng, Xiao-Dong Ma, Shuai-Shuai Zhang

Journal: Military Medical Research

PubMed ID: 41214839

Doi: 10.1186/s40779-025-00667-3

Products & Services: Protein and Antibody Isolation

Double-stranded DNA deaminase DddAE1347A can increase the efficiency and targeting range of cytidine base editors

Authors: Yuqiang Qian, Fengjiao Hui, Wenchao Niu, Di Wang, Yang Hao, Qingying Meng, Siyu Ren, Deqiang Kong, Heng Gong, Jiayu Wu, Kexin Chen, Muna Alariqi, Junping Gao, Zhanjun Li, Shuangxia Jin

Journal: Genome Biology

PubMed ID: 41250247

Doi: doi.org/10.1186/s13059-025-03849-3

Products & Services: Gene Fragments

全部