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Chromosome-Scale Genome and Comparative Transcriptomic Analysis Reveal Transcriptional Regulators of β-Carotene Biosynthesis in Mango

Authors: Xiaowei Ma, Xiang Luo, Yongzan Wei, Tuanhui Bai, Jiangli Shi, Bing Zheng, Wentian Xu, Li Li, Songbiao Wang, Jisen Zhang, Hongxia Wu

Journal: Front Plant Sci

PubMed ID: 34712262

Doi: 10.3389/fpls.2021.749108

Products & Services: Protein Tools

Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability

Authors: Deborah L Burnett, Katherine J L Jackson, David B Langley, Anupria Aggrawal, Alberto Ospina Stella, Matt D Johansen, Harikrishnan Balachandran, Helen Lenthall, Romain Rouet, Gregory Walker, Bernadette M Saunders, Mandeep Singh, Hui Li, Jake Y Henry, Jennifer Jackson, Alastair G Stewart, Franka Witthauer, Matthew A Spence, Nicole G Hansbro, Colin Jackson, Peter Schofield, Claire Milthorpe, Marianne Martinello, Sebastian R Schulz, Edith Roth, Anthony Kelleher, Sean Emery, Warwick J Britton, William D Rawlinson, Rudolfo Karl, Simon Schäfer, Thomas H Winkler, Robert Brink, Rowena A Bull, Philip M Hansbro, Hans-Martin Jäck, Stuart Turville, Daniel Christ, Christopher C Goodnow

Journal: Immunity

PubMed ID: 34788600

Doi: 10.1016/j.immuni.2021.10.019

Products & Services: Protein and Antibody Isolation

Genetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection

Authors: Elisabet Bjanes, Reyna Garcia Sillas, Rina Matsuda, Benjamin Demarco, Timothée Fettrelet, Alexandra A DeLaney, Opher S Kornfeld, Bettina L Lee, Eric M Rodríguez López, Daniel Grubaugh, Meghan A Wynosky-Dolfi, Naomi H Philip, Elise Krespan, Dorothy Tovar, Leonel Joannas, Daniel P Beiting, Jorge Henao-Mejia, Brian C Schaefer, Kaiwen W Chen, Petr Broz, Igor E Brodsky

Journal: PLoS Pathog

PubMed ID: 34648590

Doi: 10.1371/journal.ppat.1009967

Products & Services: Gene Synthesis

Deiodinase-3 is a thyrostat to regulate podocyte homeostasis

Authors: Shivangi Agarwal, Kwi Hye Koh, Nicholas J Tardi, Chuang Chen, Ranadheer Reddy Dande, Joao Pedro WerneckdeCastro, Yashwanth Reddy Sudhini, Cristina Luongo, Domenico Salvatore, Beata Samelko, Mehmet M Altintas, Steve Mangos, Antonio Bianco, Jochen Reiser

Journal: EBioMedicine

PubMed ID: 34649077

Doi: 10.1016/j.ebiom.2021.103617

Products & Services: Plasmid DNA Preparation

Brain cross-protection against SARS-CoV-2 variants by a lentiviral vaccine in new transgenic mice

Authors: Min-Wen Ku, Pierre Authié, Maryline Bourgine, François Anna, Amandine Noirat, Fanny Moncoq, Benjamin Vesin, Fabien Nevo, Jodie Lopez, Philippe Souque, Catherine Blanc, Ingrid Fert, Sébastien Chardenoux, Llta Lafosse, Delphine Cussigh, David Hardy, Kirill Nemirov, Françoise Guinet, Francina Langa Vives, Laleh Majlessi, Pierre Charneau

Journal: EMBO Mol Med

PubMed ID: 34647691

Doi: 10.15252/emmm.202114459

Products & Services: Molecular Biology Reagents

The GPR171 pathway suppresses T cell activation and limits antitumor immunity

Authors: Yuki Fujiwara, Robert J Torphy, Yi Sun, Emily N Miller, Felix Ho, Nicholas Borcherding, Tuoqi Wu, Raul M Torres, Weizhou Zhang, Richard D Schulick, Yuwen Zhu

Journal: Nat Commun

PubMed ID: 34615877

Doi: 10.1038/s41467-021-26135-9

Products & Services: Peptide Synthesis

Next generation of tumor-activating type I IFN enhances anti-tumor immune responses to overcome therapy resistance

Authors: Xuezhi Cao, Yong Liang, Zhenxiang Hu, Huiyu Li, Jiaming Yang, Eric J Hsu, Jiankun Zhu, Jin Zhou, Yang-Xin Fu

Journal: Nat Commun

PubMed ID: 34620867

Doi: 10.1038/s41467-021-26112-2

Products & Services: Endotoxin Detection & Removal System

Structural determinants of the integrin transmembrane domain required for bidirectional signal transmission across the cell membrane

Authors: Zhengli Wang, Jieqing Zhu

Journal: J Biol Chem

PubMed ID: 34678312

Doi: 10.1016/j.jbc.2021.101318

Products & Services: Protein and Antibody Isolation

Complete three-dimensional structures of the Lon protease translocating a protein substrate

Authors: Shanshan Li, Kan-Yen Hsieh, Chiao-I Kuo, Szu-Hui Lee, Grigore D Pintilie, Kaiming Zhang, Chung-I Chang

Journal: Sci Adv

PubMed ID: 34652947

Doi: 10.1126/sciadv.abj7835

Products & Services: Protein Electrophoresis and Western

Targeting folate receptor beta on monocytes/macrophages renders rapid inflammation resolution independent of root causes

Authors: Yingjuan J Lu, Leroy W Wheeler, Haiyan Chu, Paul J Kleindl, Michael Pugh, Fei You, Satish Rao, Gabriela Garcia, Henry Y Wu, Andre P da Cunha, Richard Johnson, Elaine Westrick, Vicky Cross, Alex Lloyd, Christina Dircksen, Patrick J Klein, Iontcho R Vlahov, Philip S Low, Christopher P Leamon

Journal: Cell Rep Med

PubMed ID: 34755134

Doi: 10.1016/j.xcrm.2021.100422

Products & Services: Mammalian Expression