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Potent prophylactic and therapeutic efficacy of recombinant human ACE2-Fc against SARS-CoV-2 infection in vivo

Authors: Zhaoyong Zhang, Eric Zeng, Lu Zhang, Weiming Wang, Yingkang Jin, Jiye Sun, Shuxiang Huang, Wenguang Yin, Jun Dai, Zhen Zhuang, Zhao Chen, Jing Sun, Airu Zhu, Fang Li, Weitao Cao, Xiaobo Li, Yongxia Shi, Mian Gan, Shengnan Zhang, Peilan Wei, Jicheng Huang, Nanshan Zhong, Guocai Zhong, Jingxian Zhao, Yanqun Wang, Weihui Shao, Jincun Zhao

Journal: Cell Discov

PubMed ID: 34385423

Doi: 10.1038/s41421-021-00302-0

Products & Services: Mutant Libraries

Correlation between a quantitative anti-SARS-CoV-2 IgG ELISA and neutralization activity

Authors: Ramona Dolscheid-Pommerich, Eva Bartok, Marcel Renn, Beate M Kümmerer, Bianca Schulte, Ricarda M Schmithausen, Birgit Stoffel-Wagner, Hendrik Streeck, Sandra Saschenbrecker, Katja Steinhagen, Gunther Hartmann

Journal: J Med Virol

PubMed ID: 34415572

Doi: 10.1002/jmv.27287

Comparative kinetics of SARS-CoV-2 anti-spike protein RBD IgGs and neutralizing antibodies in convalescent and naïve recipients of the BNT162b2 mRNA vaccine versus COVID-19 patients

Authors: Ioannis P Trougakos, Evangelos Terpos, Christina Zirou, Aimilia D Sklirou, Filia Apostolakou, Sentiljana Gumeni, Ioanna Charitaki, Eleni-Dimitra Papanagnou, Tina Bagratuni, Christine-Ivy Liacos, Andreas Scorilas, Eleni Korompoki, Ioannis Papassotiriou, Efstathios Kastritis, Meletios A Dimopoulos

Journal: BMC Med

PubMed ID: 34420521

Doi: 10.1186/s12916-021-02090-6

Rv0927c Inhibits NF-κB Pathway by Downregulating the Phosphorylation Level of IκBα and Enhances Mycobacterial Survival

Authors: Aihong Xia, Xin Li, Juanjuan Quan, Xiang Chen, Zhengzhong Xu, Xinan Jiao

Journal: Front Immunol

PubMed ID: 34531869

Doi: 10.3389/fimmu.2021.721370

Products & Services: Endotoxin Detection & Removal System

Cell Stress Induces Mislocalization of Transcription Factors with Mitochondrial Enrichment

Authors: Chiara Rossi, Anna Fernàndez, Pascual Torres, Omar Ramirez-Nuñez, Ana Belén Granado-Serrano, Laia Fontdevila, Mònica Povedano, Reinald Pamplona, Isidro Ferrer, Manuel Portero-Otin

Journal: Int J Mol Sci

PubMed ID: 34445555

Doi: 10.3390/ijms22168853

Products & Services: Protein Electrophoresis and Western

Structure-Guided Creation of an Anti-HA Stalk Antibody F11 Derivative That Neutralizes Both F11-Sensitive and -Resistant Influenza A(H1N1)pdm09 Viruses

Authors: Osamu Kotani, Yasushi Suzuki, Shinji Saito, Akira Ainai, Akira Ueno, Takuya Hemmi, Kaori Sano, Koshiro Tabata, Masaru Yokoyama, Tadaki Suzuki, Hideki Hasegawa, Hironori Sato

Journal: Viruses

PubMed ID: 34578314

Doi: 10.3390/v13091733

Products & Services: Gene Synthesis

Genome-wide Analysis of Basic Helix-Loop-Helix Family Genes and Expression Analysis in Response to Drought and Salt Stresses in Sieb et Zucc

Authors: Longjie Ni, Zhiquan Wang, Zekai Fu, Dina Liu, Yunlong Yin, Huogen Li, Chunsun Gu

Journal: Int J Mol Sci

PubMed ID: 34445454

Doi: 10.3390/ijms22168748

Products & Services: Molecular Biology Tools

cAMP-dependent protein kinase regulates secretion of apical membrane antigen 1 (AMA1) in Plasmodium yoelii

Authors: Takahiro Ishizaki, Masahito Asada, Hassan Hakimi, Nattawat Chaiyawong, Yuto Kegawa, Kazuhide Yahata, Osamu Kaneko

Journal: Parasitol Int

PubMed ID: 34390881

Doi: 10.1016/j.parint.2021.102435

Products & Services: Codon Optimization

BB0562 is a nutritional virulence determinant with lipase activity important for Borrelia burgdorferi infection and survival in fatty acid deficient environments

Authors: Hunter W Kuhn, Amanda G Lasseter, Philip P Adams, Carlos Flores Avile, Brandee L Stone, Darrin R Akins, Travis J Jewett, Mollie W Jewett

Journal: PLoS Pathog

PubMed ID: 34415955

Doi: 10.1371/journal.ppat.1009869

Products & Services: Catalog Antibodies

Cell-type and subcellular compartment-specific APEX2 proximity labeling reveals activity-dependent nuclear proteome dynamics in the striatum

Authors: V Dumrongprechachan, R B Salisbury, G Soto, M Kumar, M L MacDonald, Y Kozorovitskiy

Journal: Nat Commun

PubMed ID: 34381044

Doi: 10.1038/s41467-021-25144-y

Products & Services: Custom Vector Construction