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Nucleomodulin Ank13 Exploits the RaDAR Nuclear Import Pathway To Modulate Host Cell Transcription

Authors: Haley E Adcox, Amanda L Hatke, Shelby E Andersen, Sarika Gupta, Nathan B Otto, Mary M Weber, Richard T Marconi, Jason A Carlyon

Journal: MBio

PubMed ID: 34340535

Doi: 10.1128/mBio.01816-21

Products & Services: Codon Optimization

Intracellular Accumulation of IFN-λ4 Induces ER Stress and Results in Anti-Cirrhotic but Pro-HCV Effects

Authors: Olusegun O Onabajo, Fang Wang, Mei-Hsuan Lee, Oscar Florez-Vargas, Adeola Obajemu, Chizu Tanikawa, Joselin M Vargas, Shu-Fen Liao, Ci Song, Yu-Han Huang, Chen-Yang Shen, A Rouf Banday, Thomas R O'Brien, Zhibin Hu, Koichi Matsuda, Ludmila Prokunina-Olsson

Journal: Front Immunol

PubMed ID: 34497603

Doi: 10.3389/fimmu.2021.692263

Products & Services: Protein and Antibody Isolation

Neutralization of SARS-CoV-2 by highly potent, hyperthermostable, and mutation-tolerant nanobodies

Authors: Thomas Güttler, Metin Aksu, Antje Dickmanns, Kim M Stegmann, Kathrin Gregor, Renate Rees, Waltraud Taxer, Oleh Rymarenko, Jürgen Schünemann, Christian Dienemann, Philip Gunkel, Bianka Mussil, Jens Krull, Ulrike Teichmann, Uwe Groß, Volker C Cordes, Matthias Dobbelstein, Dirk Görlich

Journal: EMBO J

PubMed ID: 34302370

Doi: 10.15252/embj.2021107985

Products & Services: Recombinant Proteins

α-Synuclein kinetically regulates the nascent fusion pore dynamics

Authors: Rohith K Nellikka, Bhavya R Bhaskar, Kinjal Sanghrajka, Swapnali S Patil, Debasis Das

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34413185

Doi: 10.1073/pnas.2021742118

Products & Services: Peptide Synthesis

The extracellular innate-immune effector HMGB1 limits pathogenic bacterial biofilm proliferation

Authors: Aishwarya Devaraj, Laura A Novotny, Frank H Robledo-Avila, John R Buzzo, Lauren Mashburn-Warren, Joseph A Jurcisek, Natalia O Tjokro, Santiago Partida-Sanchez, Lauren O Bakaletz, Steven D Goodman

Journal: J Clin Invest

PubMed ID: 34396989

Doi: 10.1172/JCI140527

Products & Services: Bacterial Expression

Intravenous administration of BCG protects mice against lethal SARS-CoV-2 challenge

Authors: Kerry L Hilligan, Sivaranjani Namasivayam, Chad S Clancy, Danielle O'Mard, Sandra D Oland, Shelly J Robertson, Paul J Baker, Ehydel Castro, Nicole L Garza, Bernard A P Lafont, Reed Johnson, Franca Ronchese, Katrin D Mayer-Barber, Sonja M Best, Alan Sher

Journal: biorxiv

PubMed ID: 34494021

Doi: 10.1101/2021.08.30.458273

Products & Services: Catalog Antibodies

The Aneugenicity of Ketone Bodies in Colon Epithelial Cells Is Mediated by Microtubule Hyperacetylation and Is Blocked by Resveratrol

Authors: Haruka Sudo, Akira Kubo

Journal: Int J Mol Sci

PubMed ID: 34502304

Doi: 10.3390/ijms22179397

Products & Services: Mammalian Expression

Anillin/Mid1p interacts with the ESCRT-associated protein Vps4p and mitotic kinases to regulate cytokinesis in fission yeast

Authors: Imane M Rezig, Wandiahyel G Yaduma, Gwyn W Gould, Christopher J McInerny

Journal: Cell Cycle

PubMed ID: 34382912

Doi: 10.1080/15384101.2021.1962637

Products & Services: DNA Sequencing

Dpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes

Authors: Erika Casari, Elisa Gobbini, Marco Gnugnoli, Marco Mangiagalli, Michela Clerici, Maria Pia Longhese

Journal: Nat Commun

PubMed ID: 34362907

Doi: 10.1038/s41467-021-25090-9

Products & Services: Bacterial Expression

Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM

Authors: Aleksandar Antanasijevic, Leigh M Sewall, Christopher A Cottrell, Diane G Carnathan, Luis E Jimenez, Julia T Ngo, Jennifer B Silverman, Bettina Groschel, Erik Georgeson, Jinal Bhiman, Raiza Bastidas, Celia LaBranche, Joel D Allen, Jeffrey Copps, Hailee R Perrett, Kimmo Rantalainen, Fabien Cannac, Yuhe R Yang, Alba Torrents de la Peña, Rebeca Froes Rocha, Zachary T Berndsen, David Baker, Neil P King, Rogier W Sanders, John P Moore, Shane Crotty, Max Crispin, David C Montefiori, Dennis R Burton, William R Schief, Guido Silvestri, Andrew B Ward

Journal: Nat Commun

PubMed ID: 34376662

Doi: 10.1038/s41467-021-25087-4

Products & Services: Endotoxin Detection & Removal System