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Co-targeting of BAX and BCL-XL proteins broadly overcomes resistance to apoptosis in cancer

Authors: Andrea Lopez, Denis E Reyna, Nadege Gitego, Felix Kopp, Hua Zhou, Miguel A Miranda-Roman, Lars Ulrik Nordstrøm, Swathi-Rao Narayanagari, Ping Chi, Eduardo Vilar, Aristotelis Tsirigos, Evripidis Gavathiotis

Journal: Nat Commun

PubMed ID: 35256598

Doi: 10.1038/s41467-022-28741-7

Products & Services: Catalog Peptides

The non-ELR CXC chemokine encoded by human cytomegalovirus UL146 genotype 5 contains a C-terminal β-hairpin and induces neutrophil migration as a selective CXCR2 agonist

Authors: Christian Berg, Michael J Wedemeyer, Motiejus Melynis, Roman R Schlimgen, Lasse H Hansen, Jon Våbenø, Francis C Peterson, Brian F Volkman, Mette M Rosenkilde, Hans R Lüttichau

Journal: PLoS Pathog

PubMed ID: 35271688

Doi: 10.1371/journal.ppat.1010355

Products & Services: Custom Vector Construction

Diagnostic Host Gene Expression Analysis by Quantitative Reverse Transcription Loop-Mediated Isothermal Amplification to Discriminate between Bacterial and Viral Infections

Authors: Melissa C Remmel, Sabrina M Coyle, Mark W Eshoo, Timothy E Sweeney, David C Rawling

Journal: Clin Chem

PubMed ID: 35134876

Doi: 10.1093/clinchem/hvab275

Products & Services: Mammalian Expression

Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization

Authors: Edward A Partlow, Kevin S Cannon, Gunther Hollopeter, Richard W Baker

Journal: Nat Struct Mol Biol

PubMed ID: 35347313

Doi: 10.1038/s41594-022-00749-z

Products & Services: Peptide Synthesis

Zymomonas mobilis ZM4 Utilizes an NADP-Dependent Acetaldehyde Dehydrogenase To Produce Acetate

Authors: Magdalena M Felczak, Michaela A TerAvest

Journal: J Bacteriol

PubMed ID: 35258321

Doi: 10.1128/jb.00563-21

Products & Services: Catalog Antibodies

A simple reverse genetics method to generate recombinant coronaviruses

Authors: Julien Mélade, Géraldine Piorkowski, Franck Touret, Toscane Fourié, Jean-Sélim Driouich, Maxime Cochin, Hawa Sophia Bouzidi, Bruno Coutard, Antoine Nougairède, Xavier de Lamballerie

Journal: EMBO Rep

PubMed ID: 35239997

Doi: 10.15252/embr.202153820

Products & Services: Gene Fragments

Regulation of paternal 5mC oxidation and H3K9me2 asymmetry by ERK1/2 in mouse zygotes

Authors: Baobao Chen, Mingtian Deng, Meng-Hao Pan, Shao-Chen Sun, Honglin Liu

Journal: Cell Biosci

PubMed ID: 35255956

Doi: 10.1186/s13578-022-00758-x

Products & Services: Protein and Antibody Isolation

RUFY3 and RUFY4 are ARL8 effectors that promote coupling of endolysosomes to dynein-dynactin

Authors: Tal Keren-Kaplan, Amra Sarić, Saikat Ghosh, Chad D Williamson, Rui Jia, Yan Li, Juan S Bonifacino

Journal: Nat Commun

PubMed ID: 35314674

Doi: 10.1038/s41467-022-28952-y

Products & Services: Plasmid DNA Preparation

Circ_0060531 knockdown ameliorates IL-22-induced keratinocyte damage by binding to miR-330-5p to decrease GAB1 expression

Authors: Quan Shi, Jing Luo, Weiming Chen, Qi He, Jianwen Long, Bo Zhang

Journal: Autoimmunity

PubMed ID: 35293807

Doi: 10.1080/08916934.2022.2037127

Products & Services: Mutant Libraries

A peroxisomal heterodimeric enzyme is involved in benzaldehyde synthesis in plants

Authors: Xing-Qi Huang, Renqiuguo Li, Jianxin Fu, Natalia Dudareva

Journal: Nat Commun

PubMed ID: 35292635

Doi: 10.1038/s41467-022-28978-2

Products & Services: Codon Optimization