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Structural insight into apelin receptor-G protein stoichiometry

Authors: Yang Yue , Lier Liu , Li-Jie Wu , Yiran Wu , Ling Wang , Fei Li , Junlin Liu , Gye-Won Han , Bo Chen , Xi Lin , Rebecca L Brouillette , Émile Breault , Jean-Michel Longpré , Songting Shi , Hui Lei , Philippe Sarret , Raymond C Stevens , Michael A Hanson , Fei Xu

Journal: Nat Struct Mol Biol

PubMed ID: 35817871

Doi: 10.1038/s41594-022-00797-5

Products & Services: Peptide Synthesis

Purification, characterization, and preliminary serial crystallography diffraction advances structure determination of full-length human particulate guanylyl cyclase A receptor

Authors: Shangji Zhang, Debra T Hansen, Jose M Martin-Garcia, James D Zook, Shuchong Pan, Felicia M Craciunescu, John C Burnett, Petra Fromme

Journal: Sci Rep

PubMed ID: 35821229

Doi: 10.1038/s41598-022-15798-z

Products & Services: Insect Expression

Distinct Type I Interferon Subtypes Differentially Stimulate T Cell Responses in HIV-1-Infected Individuals

Authors: Zehra Karakoese, Mara Schwerdtfeger, Christina B Karsten, Stefan Esser, Ulf Dittmer, Kathrin Sutter

Journal: Front Immunol

PubMed ID: 35911692

Doi: 10.3389/fimmu.2022.936918

Products & Services: Mammalian Expression

gC1qR/C1qBP/HABP-1: Structural Analysis of the Trimeric Core Region, Interactions With a Novel Panel of Monoclonal Antibodies, and Their Influence on Binding to FXII

Authors: Ying Zhang, Alexander J Vontz, Ethan M Kallenberger, Xin Xu, Nicoleta T Ploscariu, Kasra X Ramyar, Brandon L Garcia, Berhane Ghebrehiwet, Brian V Geisbrecht

Journal: Front Immunol

PubMed ID: 35865516

Doi: 10.3389/fimmu.2022.887742

Products & Services: Mammalian Expression

Structure-Based Identification and Biological Characterization of New NAPRT Inhibitors

Authors: Jorge Franco, Francesco Piacente, Melanie Walter, Simone Fratta, Moustafa Ghanem, Andrea Benzi, Irene Caffa, Alexander V Kurkin, Andrea Altieri, Patrick Herr, Macarena Martínez-Bailén, Inmaculada Robina, Santina Bruzzone, Alessio Nencioni, Alberto Del Rio

Journal: Pharmaceuticals (Basel)

PubMed ID: 35890155

Doi: 10.3390/ph15070855

Products & Services: Custom Vector Construction

Mycoplasma hyopneumoniae membrane protein Mhp271 interacts with host UPR protein GRP78 to facilitate infection

Authors: Qiao Pan, Qingyuan Xu, Tong Liu, Yujuan Zhang, Jiuqing Xin

Journal: Mol Microbiol

PubMed ID: 35791781

Doi: 10.1111/mmi.14963

Products & Services: Endotoxin Detection & Removal System

Optimization of Potent and Specific Trypanothione Reductase Inhibitors: A Structure-Based Drug Discovery Approach

Authors: Theo Battista, Stefano Federico, Simone Brogi, Luca Pozzetti, Tuhina Khan, Stefania Butini, Anna Ramunno, Eleonora Fiorentino, Stefania Orsini, Trentina Di Muccio, Annarita Fiorillo, Cécile Exertier, Daniel Di Risola, Gianni Colotti, Sandra Gemma, Andrea Ilari, Giuseppe Campiani

Journal: ACS Infect Dis

PubMed ID: 35880849

Doi: 10.1021/acsinfecdis.2c00325

Products & Services: PCR Cloning and Subcloning

Grp94 Works Upstream of BiP in Protein Remodeling Under Heat Stress

Authors: Yaa S Amankwah, Preston Collins, Yasmeen Fleifil, Erin Unruh, Kevin J Ruiz Márquez, Katherine Vitou, Andrea N Kravats

Journal: J Mol Biol

PubMed ID: 35905823

Doi: 10.1016/j.jmb.2022.167762

Products & Services: Protein and Antibody Isolation

Proteomic and Phosphoproteomic Analyses Reveal Gibel Carp Responses to Cyprinid Herpesvirus 2 Infection

Authors: Chen Xu, Yiqun Li, Zidong Xiao, Jie Yang, Mingyang Xue, Nan Jiang, Yan Meng, Wenzhi Liu, Yuding Fan, Yong Zhou

Journal: J Proteome Res

PubMed ID: 35792615

Doi: 10.1021/acs.jproteome.2c00253

Products & Services: Catalog Antibodies

[C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer's disease

Authors: Tharick A Pascoal, Mira Chamoun, Elad Lax, Hsiao-Ying Wey, Monica Shin, Kok Pin Ng, Min Su Kang, Sulantha Mathotaarachchi, Andrea L Benedet, Joseph Therriault, Firoza Z Lussier, Frederick A Schroeder, Jonathan M DuBois, Baileigh G Hightower, Tonya M Gilbert, Nicole R Zürcher, Changning Wang, Robert Hopewell, Mallar Chakravarty, Melissa Savard, Emilie Thomas, Sara Mohaddes, Sarah Farzin, Alyssa Salaciak, Stephanie Tullo, A Claudio Cuello, Jean-Paul Soucy, Gassan Massarweh, Heungsun Hwang, Eliane Kobayashi, Bradley T Hyman, Bradford C Dickerson, Marie-Christine Guiot, Moshe Szyf, Serge Gauthier, Jacob M Hooker, Pedro Rosa-Neto

Journal: Nat Commun

PubMed ID: 35853847

Doi: 10.1038/s41467-022-30653-5

Products & Services: Protein Electrophoresis and Western