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Nucleic acid delivery of immune-focused SARS-CoV-2 nanoparticles drives rapid and potent immunogenicity capable of single-dose protection

Authors: Kylie M Konrath, Kevin Liaw, Yuanhan Wu, Xizhou Zhu, Susanne N Walker, Ziyang Xu, Katherine Schultheis, Neethu Chokkalingam, Himanshi Chawla, Jianqiu Du, Nicholas J Tursi, Alan Moore, Jared Adolf-Bryfogle, Mansi Purwar, Emma L Reuschel, Drew Frase, Matthew Sullivan, Benjamin Fry, Igor Maricic, Viviane M Andrade, Christel Iffland, Max Crispin, Kate E Broderick, Laurent M P F Humeau, Ami Patel, Trevor R F Smith, Jesper Pallesen, David B Weiner, Daniel W Kulp

Journal: Cell Rep

PubMed ID: 35090597

Doi: 10.1016/j.celrep.2022.110318

Products & Services: Catalog Peptides

Distribution of serotypes and antibiotic resistance of invasive Pseudomonas aeruginosa in a multi-country collection

Authors: Shamima Nasrin, Nicolas Hegerle, Shaichi Sen, Joseph Nkeze, Sunil Sen, Jasnehta Permala-Booth, Myeongjin Choi, James Sinclair, Milagritos D Tapia, J Kristie Johnson, Samba O Sow, Joshua T Thaden, Vance G Fowler, Karen A Krogfelt, Annelie Brauner, Efthymia Protonotariou, Eirini Christaki, Yuichiro Shindo, Andrea L Kwa, Sadia Shakoor, Ashika Singh-Moodley, Olga Perovic, Jan Jacobs, Octavie Lunguya, Raphael Simon, Alan S Cross, Sharon M Tennant

Journal: BMC Microbiol

PubMed ID: 34991476

Doi: 10.1186/s12866-021-02427-4

Products & Services: Molecular Biology Reagents

Three-repeat and four-repeat tau isoforms form different oligomers

Authors: Hedieh Shahpasand-Kroner, Jennifer Portillo, Carter Lantz, Paul M Seidler, Natalie Sarafian, Joseph A Loo, Gal Bitan

Journal: Protein Sci

PubMed ID: 34902187

Doi: 10.1002/pro.4257

Products & Services: Protein and Antibody Isolation

FcγRIIB potentiates differentiation of myeloid-derived suppressor cells to mediate tumor immunoescape

Authors: Lei Wu, Yanquan Xu, Huakan Zhao, Yu Zhou, Yu Chen, Shuai Yang, Juan Lei, Jiangang Zhang, Jingchun Wang, Yongzhong Wu, Yongsheng Li

Journal: Theranostics

PubMed ID: 34976216

Doi: 10.7150/thno.66575

Products & Services: Stable Cell Lines

Modulation of the Conformational Space of SARS-CoV-2 RNA Quadruplex RG-1 by Cellular Components and the Amyloidogenic Peptides α-Synuclein and hIAPP

Authors: Sanjib K Mukherjee, Jim-Marcel Knop, Roland Winter

Journal: Chemistry

PubMed ID: 34882862

Doi: 10.1002/chem.202104182

Products & Services: Mammalian Expression

A model for DHX15 mediated disassembly of A-complex spliceosomes

Authors: Hannah M Maul-Newby, Angela N Amorello, Turvi Sharma, John H Kim, Matthew S Modena, Beth E Prichard, Melissa S Jurica

Journal: RNA

PubMed ID: 35046126

Doi: 10.1261/rna.078977.121

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A Novel Peptide Derived from Induces Apoptosis in Colorectal Cancer Cells through Mitochondria and the p38 MAPK Pathway

Authors: Chunlei Li, Sirui Zhang, Jianhua Zhu, Weijuan Huang, Yuanyuan Luo, Hui Shi, Dongbo Yu, Liguo Chen, Liyan Song, Rongmin Yu

Journal: Mar Drugs

PubMed ID: 35200639

Doi: 10.3390/md20020110

Products & Services: Gene Fragments

Channelopathy-causing mutations in the SA/SB and HA/HB helices of K23 and K31 channels alter their apparent Ca sensitivity

Authors: Razan Orfali, Young-Woo Nam, Hai Minh Nguyen, Mohammad Asikur Rahman, Grace Yang, Meng Cui, Heike Wulff, Miao Zhang

Journal: Cell Calcium

PubMed ID: 35030515

Doi: 10.1016/j.ceca.2022.102538

Products & Services: Mutagenesis Services

Cross-reactive memory T cells associate with protection against SARS-CoV-2 infection in COVID-19 contacts

Authors: Rhia Kundu, Janakan Sam Narean, Lulu Wang, Joseph Fenn, Timesh Pillay, Nieves Derqui Fernandez, Emily Conibear, Aleksandra Koycheva, Megan Davies, Mica Tolosa-Wright, Seran Hakki, Robert Varro, Eimear McDermott, Sarah Hammett, Jessica Cutajar, Ryan S Thwaites, Eleanor Parker, Carolina Rosadas, Myra McClure, Richard Tedder, Graham P Taylor, Jake Dunning, Ajit Lalvani

Journal: Nat Commun

PubMed ID: 35013199

Doi: 10.1038/s41467-021-27674-x

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Recombinant porphobilinogen deaminase targeted to the liver corrects enzymopenia in a mouse model of acute intermittent porphyria

Authors: Karol M Córdoba, Irantzu Serrano-Mendioroz, Daniel Jericó, María Merino, Lei Jiang, Ana Sampedro, Manuel Alegre, Fernando Corrales, María J Garrido, Paolo G V Martini, José Luis Lanciego, Jesús Prieto, Pedro Berraondo, Antonio Fontanellas

Journal: Sci Transl Med

PubMed ID: 35020410

Doi: 10.1126/scitranslmed.abc0700

Products & Services: Gene Synthesis