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Anti-Ischemic Effects of PIK3IP1 Are Mediated through Its Interactions with the ET-PI3Kγ-AKT Axis

Authors: Jei Hyoung Park, Kyoung Jin Nho, Ji Young Lee, Yung Joon Yoo, Woo Jin Park, Chunghee Cho, Do Han Kim

Journal: Cells

PubMed ID: 35883611

Doi: 10.3390/cells11142162

Products & Services: Custom Vector Construction

Tryptophan C-mannosylation is critical for Plasmodium falciparum transmission

Authors: Sash Lopaticki, Robyn McConville, Alan John, Niall Geoghegan, Shihab Deen Mohamed, Lisa Verzier, Ryan W J Steel, Cindy Evelyn, Matthew T O'Neill, Niccolay Madiedo Soler, Nichollas E Scott, Kelly L Rogers, Ethan D Goddard-Borger, Justin A Boddey

Journal: Nat Commun

PubMed ID: 35906227

Doi: 10.1038/s41467-022-32076-8

Products & Services: Gene Synthesis

Genome-wide CRISPR Screening Reveals Pyrimidine Metabolic Reprogramming in 5-FU Chronochemotherapy of Colorectal Cancer

Authors: Ya Niu, Xinyi Fan, Yaping Wang, Jiaxin Lin, Luchun Hua, Xiaobo Li, Ruizhe Qian, Chao Lu

Journal: Front Oncol

PubMed ID: 35903686

Doi: 10.3389/fonc.2022.949715

Products & Services: Recombinant Proteins

Oral Administration with Recombinant Attenuated Regulated Delayed Lysis Vaccines Protecting against Kidney Abscess Formation

Authors: Yanchen Liang, Haochi Zhang, Na Pan, Yang Liu, Shouxin Sheng, Haotian Li, Xuemei Bao, Xiao Wang

Journal: Vaccines (Basel)

PubMed ID: 35891237

Doi: 10.3390/vaccines10071073

Products & Services: Custom Vector Construction

Overexpression of the scopoletin biosynthetic pathway enhances lignocellulosic biomass processing

Authors: Lennart Hoengenaert, Marlies Wouters, Hoon Kim, Barbara De Meester, Kris Morreel, Steven Vandersyppe, Jacob Pollier, Sandrien Desmet, Geert Goeminne, John Ralph, Wout Boerjan, Ruben Vanholme

Journal: Sci Adv

PubMed ID: 35857515

Doi: 10.1126/sciadv.abo5738

Products & Services: Custom Vector Construction

A time-resolved, multi-symbol molecular recorder via sequential genome editing

Authors: Junhong Choi, Wei Chen, Anna Minkina, Florence M Chardon, Chase C Suiter, Samuel G Regalado, Silvia Domcke, Nobuhiko Hamazaki, Choli Lee, Beth Martin, Riza M Daza, Jay Shendure

Journal: Nature

PubMed ID: 35794474

Doi: 10.1038/s41586-022-04922-8

Products & Services: CRISPR KI Templates

Pharmacokinetic Characteristics, Safety, and Tolerability of Telitacicept, an Injectable Recombinant Human B-Lymphocyte Stimulating Factor Receptor-Antibody Fusion Protein, in Healthy Chinese Subjects

Authors: Jing Xie, Xiaoyun Fan, Yue Su, Huan Zhou, Shugang Cao, Xingyu Zhu, Minhui Zhu, Cuixia He, Ying Wang, Ling Fan, Qin Ge, Juan Zhu, Bingyan Liu, Xiao Chen, Yunqiu Xie, Ling Ma, Yuanyuan Liu, Juan Chen, Huaxue Wang, Zhijun Li

Journal: Clin Pharmacol Drug Dev

PubMed ID: 35844038

Doi: 10.1002/cpdd.1136

Products & Services: Mammalian Expression

Orphan nuclear receptor NUR77 relieves insulin resistance in HTR-8/SVneo trophoblast cells through activation of autophagy and insulin signaling

Authors: Ling Li, Yu Bai, Runyu Du, Lei Tang, Ling Li

Journal: J Physiol Biochem

PubMed ID: 35902547

Doi: 10.1007/s13105-022-00901-9

Products & Services: Protein and Antibody Isolation

Structural insights into GABA transport inhibition using an engineered neurotransmitter transporter

Authors: Deepthi Joseph, Smruti Ranjan Nayak, Aravind Penmatsa