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Protective Human Anti-Poxvirus Monoclonal Antibodies Are Generated from Rare Memory B Cells Isolated by Multicolor Antigen Tetramers

Authors: Xiuling Gu, Yufan Zhang, Wei Jiang, Dongfang Wang, Jiao Lu, Guanglei Gu, Chengfeng Qin, Min Fang

Journal: Vaccines (Basel)

PubMed ID: 35891248

Doi: 10.3390/vaccines10071084

Products & Services: PCR Cloning and Subcloning

A hydrogel platform for co-delivery of immunomodulatory proteins for pancreatic islet allografts

Authors: Juan D Medina, Graham F Barber, Maria M Coronel, Michael D Hunckler, Stephen W Linderman, Michelle J Quizon, Vahap Ulker, Esma S Yolcu, Haval Shirwan, Andrés J García

Journal: J Biomed Mater Res A

PubMed ID: 35841329

Doi: 10.1002/jbm.a.37429

Products & Services: Catalog Peptides

Neoantigen Identification and Response to Adoptive Cell Transfer in Anti-PD-1 Naïve and Experienced Patients with Metastatic Melanoma

Authors: Shoshana T Levi, Amy R Copeland, Shirley Nah, Jessica S Crystal, Gabriel D Ivey, Almin Lalani, Mohammad Jafferji, Bradley S White, Neilesh B Parikh, Vid Leko, Sri Krishna, Frank Lowery, Todd D Prickett, Jared J Gartner, Li Jia, Yong F Li, Abraham Sachs, Sivasish Sindiri, Welles Robinson, Billel Gasmi, James C Yang, Stephanie L Goff, Steven A Rosenberg, Paul F Robbins

Journal: Clin Cancer Res

PubMed ID: 35247926

Doi: 10.1158/1078-0432.CCR-21-4499

Products & Services: Plasmid DNA Preparation

Non-synergy of PD-1 blockade with T-cell therapy in solid tumors

Authors: John S Davies, Farrah Karimipour, Ling Zhang, Nisha Nagarsheth, Scott Norberg, Carylinda Serna, Julius Strauss, Shinheng Chiou, James L Gulley, Christian S Hinrichs

Journal: J Immunother Cancer

PubMed ID: 35793866

Doi: 10.1136/jitc-2022-004906

Products & Services: Catalog Peptides

Low molecular weight fucoidan alleviates cerebrovascular damage by promoting angiogenesis in type 2 diabetes mice

Authors: Zhi Li, Ning Wu, Jing Wang, Yang Yue, Lihua Geng, Quanbin Zhang

Journal: Int J Biol Macromol

PubMed ID: 35841956

Doi: doi.org/10.1016/j.ijbiomac.2022.07.053

Products & Services: Protein Electrophoresis and Western

Inactive and active state structures template selective tools for the human 5-HT receptor

Authors: Shicheng Zhang, He Chen, Chengwei Zhang, Ying Yang, Petr Popov, Jing Liu, Brian E Krumm, Can Cao, Kuglae Kim, Yan Xiong, Vsevolod Katritch, Brian K Shoichet, Jian Jin, Jonathan F Fay, Bryan L Roth

Journal: Nat Struct Mol Biol

PubMed ID: 35835867

Doi: 10.1038/s41594-022-00796-6

Products & Services: Protein and Antibody Isolation

An effective strategy for the humanization of antibody fragments under an accelerated timeline

Authors: Isabella Gizzi Jiacomini, Martina Beltramino, Fanny Boursin, João Carlos Minozzo, Juliana Ferreira de Moura, Philippe Billiald, Larissa Magalhães Alvarenga, Nicolas Aubrey

Journal: Int J Biol Macromol

PubMed ID: 35803408

Doi: 10.1016/j.ijbiomac.2022.06.195

Products & Services: Custom Vector Construction

Endothelial PHD2 deficiency induces nitrative stress suppression of caveolin-1 in pulmonary hypertension

Authors: Bin Liu, Yi Peng, Dan Yi, Narsa Machireddy, Daoyin Dong, Karina Ramirez, Jingbo Dai, Rebecca Vanderpool, Maggie M Zhu, Zhiyu Dai, You-Yang Zhao

Journal: Eur Respir J

PubMed ID: 35798360

Doi: 10.1183/13993003.02643-2021

Products & Services: Synthetic Guide RNA

Human-type sialic acid receptors contribute to avian influenza A virus binding and entry by hetero-multivalent interactions

Authors: Mengying Liu, Liane Z X Huang, Anthony A Smits, Christian Büll, Yoshiki Narimatsu, Frank J M van Kuppeveld, Henrik Clausen, Cornelis A M de Haan, Erik de Vries

Journal: Nat Commun

PubMed ID: 35831293

Doi: 10.1038/s41467-022-31840-0

Products & Services: Mammalian Expression

A Warhead Substitution Study on the Coronavirus Main Protease Inhibitor Nirmatrelvir

Authors: Subramanyam Vankadara, Monique Danielle Dawson, Jia Yi Fong, Qin Yao Oh, Qi An Ang, Boping Liu, Hong Yun Chang, Judice Koh, Xiaoying Koh, Qian Wen Tan, Joma Joy, Cheng San Brian Chia

Journal: ACS Med Chem Lett

PubMed ID: 35971455

Doi: 10.1021/acsmedchemlett.2c00260

Products & Services: Peptide Synthesis