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Olfactory Information Storage Engages Subcortical and Cortical Brain Regions That Support Valence Determination

Authors: Christina Strauch, Thu-Huong Hoang, Frank Angenstein, Denise Manahan-Vaughan

Journal: Cereb Cortex

PubMed ID: 34379749

Doi: 10.1093/cercor/bhab226

Products & Services: Plasmid DNA Preparation

Vaccine Candidate Double Mutant Variants of Enterotoxigenic Heat-Stable Toxin

Authors: Ephrem Debebe Zegeye, Yuleima Diaz, Pål Puntervoll

Journal: Vaccines (Basel)

PubMed ID: 35214698

Doi: 10.3390/vaccines10020241

Products & Services: Mutant Libraries

Structural characterization of a new subclass of panicum mosaic virus-like 3' cap-independent translation enhancer

Authors: Philip Z Johnson, Wojciech K Kasprzak, Bruce A Shapiro, Anne E Simon

Journal: Nucleic Acids Res

PubMed ID: 35104872

Doi: 10.1093/nar/gkac007

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Performance evaluation of four surrogate Virus Neutralization Tests (sVNTs) in comparison to the gold standard test

Authors: Massimo Pieri, Maria Infantino, Mariangela Manfredi, Marzia Nuccetelli, Valentina Grossi, Barbara Lari, Flaminia Tomassetti, Serena Sarubbi, Edda Russo, Amedeo Amedei, Maurizio Benucci, Patrizia Casprini, Lorenzo Stacchini, Concetta Castilletti, Sergio Bernardini

Journal: Front Biosci (Landmark Ed)

PubMed ID: 35227017

Doi: 10.31083/j.fbl2702074

IL-11 Is Elevated and Drives the Profibrotic Phenotype Transition of Orbital Fibroblasts in Thyroid-Associated Ophthalmopathy

Authors: Pengsen Wu, Bingying Lin, Siyu Huang, Jie Meng, Fan Zhang, Min Zhou, Xiangqing Hei, Yu Ke, Huasheng Yang, Danping Huang

Journal: Front Endocrinol (Lausanne)

PubMed ID: 35273577

Doi: 10.3389/fendo.2022.846106

Products & Services: Proteins, Expression, Isolation and Analysis

Nonswelling and Hydrolytically Stable Hydrogels Uncover Cellular Mechanosensing in 3D

Authors: Hongyan Long, Bart E Vos, Timo Betz, Brendon M Baker, Britta Trappmann

Journal: Adv Sci (Weinh)

PubMed ID: 35187856

Doi: 10.1002/advs.202105325

Products & Services: Recombinant Proteins

The Cdc42 GTPase-activating protein Rga6 promotes the cortical localization of septin

Authors: Shengnan Zheng, Biyu Zheng, Zhenbang Liu, Xiaopeng Ma, Xing Liu, Xuebiao Yao, Wenfan Wei, Chuanhai Fu

Journal: J Cell Sci

PubMed ID: 35048989

Doi: 10.1242/jcs.259228

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Fine mapping and cloning of the major seed protein quantitative trait loci on soybean chromosome 20

Authors: Christina E Fliege, Russell A Ward, Pamela Vogel, Hanh Nguyen, Truyen Quach, Ming Guo, João Paulo Gomes Viana, Lucas Borges Dos Santos, James E Specht, Tom E Clemente, Matthew E Hudson, Brian W Diers

Journal: Plant J

PubMed ID: 34978122

Doi: 10.1111/tpj.15658

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Induced ligno-suberin vascular coating and tyramine-derived hydroxycinnamic acid amides restrict Ralstonia solanacearum colonization in resistant tomato

Authors: Anurag Kashyap, Álvaro Luis Jiménez-Jiménez, Weiqi Zhang, Montserrat Capellades, Sumithra Srinivasan, Anna Laromaine, Olga Serra, Mercè Figueras, Jorge Rencoret, Ana Gutiérrez, Marc Valls, Nuria S Coll

Journal: New Phytol

PubMed ID: 35152435

Doi: 10.1111/nph.17982

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Synthetic virions reveal fatty acid-coupled adaptive immunogenicity of SARS-CoV-2 spike glycoprotein

Authors: Oskar Staufer, Kapil Gupta, Jochen Estebano Hernandez Bücher, Fabian Kohler, Christian Sigl, Gunjita Singh, Kate Vasileiou, Ana Yagüe Relimpio, Meline Macher, Sebastian Fabritz, Hendrik Dietz, Elisabetta Ada Cavalcanti Adam, Christiane Schaffitzel, Alessia Ruggieri, Ilia Platzman, Imre Berger, Joachim P Spatz

Journal: Nat Commun

PubMed ID: 35165285

Doi: 10.1038/s41467-022-28446-x

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A Lateral Flow Immunoassay Coupled with a Spectrum-Based Reader for SARS-CoV-2 Neutralizing Antibody Detection

Authors: Rui-Lin Huang, Yi-Chen Fu, Yung-Chih Wang, Chitsung Hong, Wei-Chieh Yang, I-Jen Wang, Jun-Ren Sun, Yunching Chen, Ching-Fen Shen, Chao-Min Cheng

Journal: Vaccines (Basel)

PubMed ID: 35214731

Doi: 10.3390/vaccines10020271

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Molecular recognition of formylpeptides and diverse agonists by the formylpeptide receptors FPR1 and FPR2

Authors: Youwen Zhuang, Lei Wang, Jia Guo, Dapeng Sun, Yue Wang, Weiyi Liu, H Eric Xu, Cheng Zhang

Journal: Nat Commun

PubMed ID: 35217703

Doi: 10.1038/s41467-022-28586-0

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N-terminal phosphorylation regulates the activity of glycogen synthase kinase 3 from Plasmodium falciparum

Authors: Samuel Pazicky, Arne Alder, Haydyn Mertens, Dmitri Svergun, Tim Gilberger, Christian Löw

Journal: Biochem J

PubMed ID: 35023554

Doi: 10.1042/BCJ20210829

Products & Services: Mutant Libraries

Cotranslational interaction of human EBP50 and ezrin overcomes masked binding site during complex assembly

Authors: Krishnendu Khan, Briana Long, Camelia Baleanu-Gogonea, Valentin Gogonea, Gauravi M Deshpande, Kommireddy Vasu, Paul L Fox

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35140182

Doi: 10.1073/pnas.2115799119

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Hot Hydrogen Atom Irradiation of Protonated/Deprotonated Peptide in an Ion Trap Facilitates Fragmentation through Heated Radical Formation

Authors: Daiki Asakawa, Hidenori Takahashi, Shinichi Iwamoto, Koichi Tanaka

Journal: J Am Chem Soc

PubMed ID: 35138819

Doi: 10.1021/jacs.1c11081

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Molecular Characterization and Gene Expression Analysis of Aquaporin in

Authors: Qingli Niu, Rongzeng Hao, Yuping Pan, Zhijie Liu, Jifei Yang, Guiquan Guan, Jianxun Luo, Hong Yin

Journal: Front Physiol

PubMed ID: 35250616

Doi: 10.3389/fphys.2022.811628

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Systemic and Lower Respiratory Tract Immunity to SARS-CoV-2 Omicron and Variants in Pediatric Severe COVID-19 and Mis-C

Authors: Juanjie Tang, Adrienne G Randolph, Tanya Novak, Tracie C Walker, Laura L Loftis, Matt S Zinter, Katherine Irby, Surender Khurana

Journal: Vaccines (Basel)

PubMed ID: 35214728

Doi: 10.3390/vaccines10020270

Products & Services: Mammalian Expression

Endothelial Phospholipase Cγ2 Improves Outcomes of Diabetic Ischemic Limb Rescue Following VEGF Therapy

Authors: Yashika Rustagi, Ahmed S Abouhashem, Priyanka Verma, Sumit S Verma, Edward Hernandez, Sheng Liu, Manishekhar Kumar, Poornachander R Guda, Rajneesh Srivastava, Sujit K Mohanty, Sedat Kacar, Sanskruti Mahajan, Kristen E Wanczyk, Savita Khanna, Michael P Murphy, Gayle M Gordillo, Sashwati Roy, Jun Wan, Chandan K Sen, Kanhaiya Singh

Journal: Diabetes

PubMed ID: 35192691

Doi: 10.2337/db21-0830

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Ratiometric Imaging of Mitochondrial Hydrogen Peroxide in Aβ-Mediated Neurotoxicity

Authors: Xinyu Li, Yiyu Zhang, Hui-Wang Ai

Journal: ACS Sens

PubMed ID: 35226474

Doi: 10.1021/acssensors.1c01381

Products & Services: Mammalian Expression

Polarized epithelium-sperm co-culture system reveals stimulatory factors for the secretion of mouse epididymal quiescin sulfhydryl oxidase 1

Authors: Yu-Syuan Wei, Wan-Zhen Lin, Tse-En Wang, Wei-Yun Lee, Sheng-Hsiang Li, Fu-Jung Lin, Brett Nixon, Petra Sipilä, Pei-Shiue Tsai

Journal: J Reprod Dev

PubMed ID: 35228412

Doi: 10.1262/jrd.2021-128

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Hsa_circ_0007059 promotes apoptosis and inflammation in cardiomyocytes during ischemia by targeting microRNA-378 and microRNA-383

Authors: Chaorui Xu, Zhuowen Jia, Xuefei Cao, Sha Wang, Jipeng Wang, Liping An

Journal: Cell Cycle

PubMed ID: 35192424

Doi: 10.1080/15384101.2022.2040122

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Rapid colloidal gold immunochromatographic assay for the detection of SARS-CoV-2 total antibodies after vaccination

Authors: Liya Ye, Xinxin Xu, Shanshan Song, Liguang Xu, Hua Kuang, Chuanlai Xu

Journal: J Mater Chem B

PubMed ID: 35212337

Doi: 10.1039/d1tb02521j

Products & Services: Proteins, Expression, Isolation and Analysis

Adaptive evolution of Methylotuvimicrobium alcaliphilum to grow in the presence of rhamnolipids improves fatty acid and rhamnolipid production from CH4

Authors: Deepika Awasthi, Yung-Hsu Tang, Bashar Amer, Edward E K Baidoo, Jennifer Gin, Yan Chen, Christopher J Petzold, Marina Kalyuzhnaya, Steven W Singer

Journal: J Ind Microbiol Biotechnol

PubMed ID: 35134957

Doi: 10.1093/jimb/kuac002

Products & Services: Bacterial Expression

PAD-2-mediated citrullination of nucleophosmin provides an effective target for tumor immunotherapy

Authors: Ruhul H Choudhury, Peter Symonds, Samantha J Paston, Ian Daniels, Katherine W Cook, Mohamed Gijon, Rachael L Metheringham, Victoria A Brentville, Lindy G Durrant

Journal: J Immunother Cancer

PubMed ID: 35140112

Doi: 10.1136/jitc-2021-003526

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Human cardiac myosin-binding protein C phosphorylation- and mutation-dependent structural dynamics monitored by time-resolved FRET

Authors: Rhye-Samuel Kanassatega, Thomas A Bunch, Victoria C Lepak, Christopher Wang, Brett A Colson

Journal: J Mol Cell Cardiol

PubMed ID: 35227736

Doi: 10.1016/j.yjmcc.2022.02.005

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Highly Stable Buffer-Based Zinc Oxide/Reduced Graphene Oxide Nanosurface Chemistry for Rapid Immunosensing of SARS-CoV-2 Antigens

Authors: Fatemeh Haghayegh, Razieh Salahandish, Mohsen Hassani, Amir Sanati-Nezhad

Journal: ACS Appl Mater Interfaces

PubMed ID: 35172574

Doi: 10.1021/acsami.1c24475

Products & Services: Proteins, Expression, Isolation and Analysis

Identification and mapping of post-transcriptional modifications on the HIV-1 antisense transcript Ast in human cells

Authors: Mariana Estevez, Rui Li, Biplab Paul, Kaveh Daneshvar, Alan C Mullen, Fabio Romerio, Balasubrahmanyam Addepalli

Journal: RNA

PubMed ID: 35168996

Doi: 10.1261/rna.079043.121

Products & Services: Gene Synthesis

APLNR Regulates IFN-γ signaling via β-arrestin 1 mediated JAK-STAT1 pathway in melanoma cells

Authors: Yingying Liu, Xiaochuan Ma, Hui Yang, Xun Li, Yingli Ma, Brandon Ason, Suling Liu, Liaoyuan A Hu

Journal: Biochem J

PubMed ID: 35084016

Doi: 10.1042/BCJ20210813

Products & Services: Gene Synthesis

Genome-wide identification and functional characterization of gene family reveal their involvement in response to drought stress in

Authors: Guangzhen Shi, Xinxia Zhu

Journal: PeerJ

PubMed ID: 35186477

Doi: 10.7717/peerj.12883

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CREG mitigates neonatal HIE injury through survival promotion and apoptosis inhibition in hippocampal neurons via activating AKT signaling

Authors: Dan Chen, Yi Zhang, Lian Ji, Yubin Wu

Journal: Cell Biol Int

PubMed ID: 35143104

Doi: 10.1002/cbin.11777

Products & Services: Gene Synthesis

CREG mitigates neonatal HIE injury through survival promotion and apoptosis inhibition in hippocampal neurons via activating AKT signaling

Authors: Dan Chen, Yi Zhang, Lian Ji, Yubin Wu

Journal: Cell Biol Int

PubMed ID: 35143104

Doi: 10.1002/cbin.11777

Products & Services: Gene Synthesis

Base excision repair system targeting DNA adducts of trioxacarcin/LL-D49194 antibiotics for self-resistance

Authors: Xiaorong Chen, Noah P Bradley, Wei Lu, Katherine L Wahl, Mei Zhang, Hua Yuan, Xian-Feng Hou, Brandt F Eichman, Gong-Li Tang

Journal: Nucleic Acids Res

PubMed ID: 35191495

Doi: 10.1093/nar/gkac085

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Cathepsin B inhibitor alleviates Th1, Th17, and Th22 transcription factor signaling dysregulation in experimental autoimmune encephalomyelitis

Authors: Mushtaq A Ansari, Ahmed Nadeem, Musaad A Alshammari, Sabry M Attia, Saleh A Bakheet, Mohammad R Khan, Thamer H Albekairi, Abdullah F Alasmari, Khaled Alhosaini, Faleh Alqahtani, Haneen A Al-Mazroua, Sheikh F Ahmad

Journal: Exp Neurol

PubMed ID: 35122866

Doi: 10.1016/j.expneurol.2022.113997

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Serum TK1 protein and C-reactive protein correlate to treatment response and predict survival in dogs with hematologic malignancies

Authors: S Saellström, H Sharif, K K Jagarlamudi, H Rönnberg, L Wang, S Eriksson

Journal: Res Vet Sci

PubMed ID: 35245727

Doi: 10.1016/j.rvsc.2022.02.019

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Rapid screening of aptamers for fluorescent targets by integrated digital PCR and flow cytometry

Authors: Xiaona Fang, Wenjing Li, Tian Gao, Qurat Ul Ain Zahra, Zhaofeng Luo, Renjun Pei

Journal: Talanta

PubMed ID: 35180537

Doi: 10.1016/j.talanta.2022.123302

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Immunological characterization of chicken tumor necrosis factor-α (TNF-α) using new sets of monoclonal antibodies specific for poultry TNF-α

Authors: Mingmin Lu, Youngsub Lee, Charles Li, Hyun S Lillehoj

Journal: Dev Comp Immunol

PubMed ID: 35157961

Doi: 10.1016/j.dci.2022.104374

Products & Services: Proteins, Expression, Isolation and Analysis

Lanthanide-based β-Tricalcium Phosphate Upconversion Nanoparticles as an Effective Theranostic Nonviral Vectors for Image-Guided Gene Therapy

Authors: Flavia Rodrigues Oliveira Silva, Nelson Batista Lima, Maria Helena Bellini, Luiz Felipe Silva Teixeira, Eric Yiwei Du, Niloufar Jamshidi, Justin Gooding, Adam David Martin, Alexander Macmillan, Christopher Peter Marquis, Pall Thordarson

Journal: Nanotheranostics

PubMed ID: 35223382

Doi: 10.7150/ntno.68789

Products & Services: Mammalian Expression

Ligation-assisted homologous recombination enables precise genome editing by deploying both MMEJ and HDR

Authors: Zhihan Zhao, Peng Shang, Fanny Sage, Niels Geijsen

Journal: Nucleic Acids Res

PubMed ID: 35212386

Doi: 10.1093/nar/gkac118

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Dioscin promotes autophagy by regulating the AMPK-mTOR pathway in ulcerative colitis

Authors: Han Li, Bo Pang, Bin Nie, Shifang Qu, Kuanxin Zhang, Jinxiu Xu, Ming Yang, Jie Liu, Shasha Li

Journal: Immunopharmacol Immunotoxicol

PubMed ID: 35174751

Doi: 10.1080/08923973.2022.2037632

Products & Services: Proteins, Expression, Isolation and Analysis

Dioscin promotes autophagy by regulating the AMPK-mTOR pathway in ulcerative colitis

Authors: Han Li, Bo Pang, Bin Nie, Shifang Qu, Kuanxin Zhang, Jinxiu Xu, Ming Yang, Jie Liu, Shasha Li

Journal: Immunopharmacol Immunotoxicol

PubMed ID: 35174751

Doi: 10.1080/08923973.2022.2037632

Products & Services: Proteins, Expression, Isolation and Analysis

Metal Dependence and Functional Diversity of Type I Cas3 Nucleases

Authors: Sining Sun, Zunyu He, Paul Jiang, Rishika Baral, Maria-Eirini Pandelia

Journal: Biochemistry

PubMed ID: 35184547

Doi: 10.1021/acs.biochem.1c00779

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Development of a Test Card Based on Colloidal Gold Immunochromatographic Strips for Rapid Detection of Antibodies against Theileria equi and Babesia caballi

Authors: Guangpu Yang, Kewei Chen, Wei Guo, Zhe Hu, Ting Qi, Diqiu Liu, Yaoxin Wang, Cheng Du, Xiaojun Wang

Journal: Microbiol Spectr

PubMed ID: 35196786

Doi: 10.1128/spectrum.02411-21

Products & Services: Proteins, Expression, Isolation and Analysis

Dexmedetomidine inhibits the growth and metastasis of esophageal cancer cells by down-regulation of lncRNA MALAT1

Authors: Wei Zhang, Li Zhang, Xiao-Jun Cai, Dong Li, Feng-Jun Cao, Zhi-Gang Zuo, Ying Song, Xiong-Jie Yu, Shan Liu

Journal: Kaohsiung J Med Sci

PubMed ID: 35199933

Doi: 10.1002/kjm2.12506

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Crystal packing reveals rapamycin-mediated homodimerization of an FK506-binding domain

Authors: Ajit Kumar Singh, Ketul Saharan, Somanath Baral, Sheng Luan, Dileep Vasudevan

Journal: Int J Biol Macromol

PubMed ID: 35218805

Doi: 10.1016/j.ijbiomac.2022.02.107

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Inhibition of the Interaction of TREM-1 and eCIRP Attenuates Inflammation and Improves Survival in Hepatic Ischemia/Reperfusion

Authors: Timothy Borjas, Asha Jacob, HaoTing Yen, Vihas Patel, Gene F Coppa, Monowar Aziz, Ping Wang

Journal: Shock

PubMed ID: 34864782

Doi: 10.1097/SHK.0000000000001894

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Dexmedetomidine inhibits the growth and metastasis of esophageal cancer cells by down-regulation of lncRNA MALAT1

Authors: Wei Zhang, Li Zhang, Xiao-Jun Cai, Dong Li, Feng-Jun Cao, Zhi-Gang Zuo, Ying Song, Xiong-Jie Yu, Shan Liu

Journal: Kaohsiung J Med Sci

PubMed ID: 35199933

Doi: 10.1002/kjm2.12506

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Characterization of the pVHL Interactome in Human Testis Using High-Throughput Library Screening

Authors: Antonella Falconieri, Giovanni Minervini, Federica Quaglia, Geppo Sartori, Silvio C E Tosatto

Journal: Cancers (Basel)

PubMed ID: 35205757

Doi: 10.3390/cancers14041009

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OmpA may be used as a novel target to enrich and detect Escherichia coli in milk samples

Authors: Yichen Tian, Kaiqing Yang, Yaoqiang Shi, Jinyang Zhang, Qinqin Han, Xueshan Xia, Yuzhu Song

Journal: J Dairy Sci

PubMed ID: 35151480

Doi: 10.3168/jds.2021-20974

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Cytolysin A-mediated protein exportation efficiency and its role in enhancing the fitness of live recombinant Salmonella Typhi vaccine strain

Authors: F-K Loh, S Nathan, S-C Chow, C-M Fang

Journal: Lett Appl Microbiol

PubMed ID: 35138654

Doi: 10.1111/lam.13669

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Enhanced transglycosylation activity of an Endo-F3 mutant by ligand-directed localization

Authors: Xiangman Zou, Zhi Liu, Liya Liu, Wei Shi, Wanzhen Li, Zifen Guo, Feng Tang, Wei Huang

Journal: Org Biomol Chem

PubMed ID: 35166761

Doi: 10.1039/d2ob00030j

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Quantifying Neutralizing Antibodies in Patients with COVID-19 by a Two-Variable Generalized Additive Model

Authors: Kuan-Ting Liu, Yu-Nong Gong, Chung-Guei Huang, Peng-Nien Huang, Kar-Yee Yu, Hou-Chen Lee, Sun-Che Lee, Huan-Jung Chiang, Yu-An Kung, Yueh-Te Lin, Mei-Jen Hsiao, Po-Wei Huang, Sheng-Yu Huang, Hsin-Tai Wu, Chih-Ching Wu, Rei-Lin Kuo, Kuan-Fu Chen, Chuan-Tien Hung, Kasopefoluwa Y Oguntuyo, Christian S Stevens, Shreyas Kowdle, Hsin-Ping Chiu, Benhur Lee, Guang-Wu Chen, Shin-Ru Shih

Journal: mSphere

PubMed ID: 35107336

Doi: 10.1128/msphere.00883-21

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Charge-Modulated Accessibility of Tyrosine Residues for Silk-Elastin Copolymer Cross-Linking

Authors: Constancio Gonzalez-Obeso, Fredrik G Backlund, David L Kaplan

Journal: Biomacromolecules

PubMed ID: 35113522

Doi: 10.1021/acs.biomac.1c01192

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SARS-CoV-2 neutralizing capacity among blood donors without prior COVID-19 symptomatic history vs blood donors with prior COVID-19 symptomatic history: A comparative study

Authors: Ushasree Ravula, Srinivasa Rao Chunchu, Srujaleswari Mooli, Ravi Naik, Pandu Ranga Rao Sarangapati

Journal: Transfus Clin Biol

PubMed ID: 35167958

Doi: 10.1016/j.tracli.2022.02.004

Melanocortin receptor agonists suppress experimental autoimmune uveitis

Authors: Tat Fong Ng, Kaleb Dawit, Andrew W Taylor

Journal: Exp Eye Res

PubMed ID: 35196505

Doi: 10.1016/j.exer.2022.108986

Products & Services: Mammalian Expression

Impact of the clinically approved Petasites hybridus extract Ze 339 on intestinal mechanisms involved in the handling of histamine

Authors: Lina G Mettler, Karin Brecht, Veronika Butterweck, Henriette E Meyer Zu Schwabedissen

Journal: Biomed Pharmacother

PubMed ID: 35149385

Doi: 10.1016/j.biopha.2022.112698

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IL-4 plays an essential role in DnaJ-ΔA146Ply-mediated immunoprotection against Streptococcus pneumoniae in mice

Authors: Yi Hu, Lian Li, Wenchun Xu, Kaifeng Wu, Jiangming Xiao, Yang Peng, Yusi Liu, Yibing Yin, Xuemei Zhang

Journal: Mol Immunol

PubMed ID: 35114487

Doi: 10.1016/j.molimm.2022.01.010

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The interplay of viral loads, clinical presentation, and serological responses in SARS-CoV-2 - Results from a prospective cohort of outpatient COVID-19 cases

Authors: Kerstin Puchinger, Noemi Castelletti, Raquel Rubio-Acero, Christof Geldmacher, Tabea M Eser, Flora Deák, Ivana Paunovic, Abhishek Bakuli, Elmar Saathoff, Alexander von Meyer, Alisa Markgraf, Philine Falk, Jakob Reich, Friedrich Riess, Philipp Girl, Katharina Müller, Katja Radon, Jessica Michelle Guggenbuehl Noller, Roman Wölfel, Michael Hoelscher, Inge Kroidl, Andreas Wieser, Laura Olbrich

Journal: Virology

PubMed ID: 35245784

Doi: 10.1016/j.virol.2022.02.002

Knockdown of long non‑coding RNA DDX11‑AS1 inhibits the proliferation, migration and paclitaxel resistance of breast cancer cells by upregulating microRNA‑497 expression

Authors: Meng Liang, Beibei Zhu, Min Wang, Ju Jin

Journal: Mol Med Rep

PubMed ID: 35169864

Doi: 10.3892/mmr.2022.12639

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Knockdown of long non‑coding RNA DDX11‑AS1 inhibits the proliferation, migration and paclitaxel resistance of breast cancer cells by upregulating microRNA‑497 expression

Authors: Meng Liang, Beibei Zhu, Min Wang, Ju Jin

Journal: Mol Med Rep

PubMed ID: 35169864

Doi: 10.3892/mmr.2022.12639

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Biochemical Screening of Potent Zika Virus Protease Inhibitors

Authors: Camila Coelho, Gloria Gallo, Leon Hardy, Maria Elena Bottazzi, Claudia Campos, Martin Würtele

Journal: ChemMedChem

PubMed ID: 35104396

Doi: 10.1002/cmdc.202100695

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Long noncoding RNASEH1-AS1 exacerbates the progression of non-small cell lung cancer by acting as a ceRNA to regulate microRNA-516a-5p/FOXK1 and thereby activating the Wnt/β-catenin signaling pathway

Authors: Chan Zhang, Jian Huang, Ke Lou, Hui Ouyang

Journal: Cancer Med

PubMed ID: 35166053

Doi: 10.1002/cam4.4509

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Circular dichroism spectroscopic assessment of structural changes upon protein thermal unfolding at contrasting pH: Comparison with molecular dynamics simulations

Authors: Ponciano García-Gutiérrez, Menandro Camarillo-Cadena, Liliana I Vera-Robles, Rafael A Zubillaga, Andrés Hernández-Arana

Journal: Spectrochim Acta A Mol Biomol Spectrosc

PubMed ID: 35245803

Doi: 10.1016/j.saa.2022.121039

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Imatinib disturbs lysosomal function and morphology and impairs the activity of mTORC1 in human hepatocyte cell lines

Authors: Noëmi Johanna Roos, Riccardo Vincenzo Mancuso, Gerda Mawududzi Sanvee, Jamal Bouitbir, Stephan Krähenbühl

Journal: Food Chem Toxicol

PubMed ID: 35182693

Doi: 10.1016/j.fct.2022.112869

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Molecular characterization of the serotonergic transporter from the cestode Echinococcus granulosus: pharmacology and potential role in the nervous system

Authors: Federico Camicia, Hugo R Vaca, Ines Guarnaschelli, Uriel Koziol, Ole V Mortensen, Andreia C K Fontana

Journal: Parasitol Res

PubMed ID: 35169884

Doi: 10.1007/s00436-022-07466-y

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Molecular characterization of the serotonergic transporter from the cestode Echinococcus granulosus: pharmacology and potential role in the nervous system

Authors: Federico Camicia, Hugo R Vaca, Ines Guarnaschelli, Uriel Koziol, Ole V Mortensen, Andreia C K Fontana

Journal: Parasitol Res

PubMed ID: 35169884

Doi: 10.1007/s00436-022-07466-y

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Alterations in calmodulin-cardiac ryanodine receptor molecular recognition in congenital arrhythmias

Authors: Giuditta Dal Cortivo , Carlo Giorgio Barracchia , Valerio Marino , Mariapina D'Onofrio , Daniele Dell'Orco

Journal: Cell Mol Life Sci

PubMed ID: 35133504

Doi: 10.1007/s00018-022-04165-w

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The Structure of the Arabidopsis PEX4-PEX22 Peroxin Complex—Insights Into Ubiquitination at the Peroxisomal Membrane

Authors: Melissa S Traver , Sarah E Bradford , Jose Luis Olmos Jr , Zachary J Wright , Mitchell D Miller , Weijun Xu , George N Phillips Jr , Bonnie Bartel

Journal: Front Cell Dev Biol

PubMed ID: 35300425

Doi: 10.3389/fcell.2022.838923

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A continuous assay set to screen and characterize novel protein N-acetyltransferases unveils rice GNAT2 activity

Authors: Thomas Asensio , Cyril Dian , Jean-Baptiste Boyer , Frédéric Rivière, Thierry Meinnel , Carmela Giglione

Journal: Front Plant Sci

PubMed ID: 35273627

Doi: 10.3389/fpls.2022.832144

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Exploring Noncovalent Protease Inhibitors for the Treatment of Severe Acute Respiratory Syndrome and Severe Acute Respiratory Syndrome-Like Coronaviruses

Authors: Brendan T Freitas, Daniil A Ahiadorme, Rahul S Bagul, Ian A Durie, Samir Ghosh, Jarvis Hill, Naomi E Kramer, Jackelyn Murray, Brady M O'Boyle, Emmanuel Onobun, Michael G Pirrone, Justin D Shepard, Suzanne Enos, Yagya P Subedi, Kapil Upadhyaya, Ralph A Tripp, Brian S Cummings, David Crich, Scott D Pegan

Journal: ACS Infect Dis

PubMed ID: 35199517

Doi: 10.1021/acsinfecdis.1c00631

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DCHS1, Lix1L, and the Septin Cytoskeleton: Molecular and Developmental Etiology of Mitral Valve Prolapse

Authors: Kelsey S Moore, Reece Moore, Diana B Fulmer, Lilong Guo, Cortney Gensemer, Rebecca Stairley, Janiece Glover, Tyler C Beck, Jordan E Morningstar, Rachel Biggs, Rupak Muhkerjee, Alexander Awgulewitsch, Russell A Norris

Journal: J Cardiovasc Dev Dis

PubMed ID: 35200715

Doi: 10.3390/jcdd9020062

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Biochemical and Biophysical Characterisation of the Hepatitis E Virus Guanine-7-Methyltransferase

Authors: Preeti Hooda, Mohd Ishtikhar, Shweta Saraswat, Pooja Bhatia, Deepali Mishra, Aditya Trivedi, Rajkumar Kulandaisamy, Soumya Aggarwal, Manoj Munde, Nemat Ali, Abdullah F AlAsmari, Mohd A Rauf, Krishna K Inampudi, Deepak Sehgal

Journal: Molecules

PubMed ID: 35268608

Doi: 10.3390/molecules27051505

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Comprehensive mapping of SARS-CoV-2 peptide epitopes for development of a highly sensitive serological test for total and neutralizing antibodies

Authors: Garima Kumar, Sarah Sterrett, Lucinda Hall, Edlue Tabengwa, Kazuhito Honjo, Michael Larimer, Randall S Davis, Paul A Goepfert, Benjamin M Larimer

Journal: Protein Eng Des Sel

PubMed ID: 35174857

Doi: 10.1093/protein/gzab033

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Systematic profiling of antigen bias in humoral response against SARS-CoV-2

Authors: Nana Wei, Qiujing Wang, Zhibing Lin, Liyun Xu, Zheen Zhang, Yan Wang, Zhejuan Yang, Lue Li, Tingxiao Zhao, Lu Wang, Haifei Lou, Mingfang Han, Mingliang Ma, Yaosheng Jiang, Jinmiao Lu, Shilan Zhu, Li Cui, Shibo Li

Journal: Virus Res

PubMed ID: 35176329

Doi: 10.1016/j.virusres.2022.198711

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Non-Invasive Monitoring for Rejection in Kidney Transplant Recipients After SARS-CoV-2 mRNA Vaccination

Authors: Ayman Al Jurdi, Rodrigo B Gassen, Thiago J Borges, Zhabiz Solhjou, Frank E Hullekes, Isadora T Lape, Orhan Efe, Areej Alghamdi, Poojan Patel, John Y Choi, Mostafa T Mohammed, Brigid Bohan, Vikram Pattanayak, Ivy Rosales, Paolo Cravedi, Camille N Kotton, Jamil R Azzi, Leonardo V Riella

Journal: Front Immunol

PubMed ID: 35281011

Doi: 10.3389/fimmu.2022.838985

miR-145-5p inhibits the proliferation of glioma stem cells by targeting translationally controlled tumor protein

Authors: Qiujian Zhang, Zhe Cheng, Lei Shi, Gengsheng Mao

Journal: J Cancer

PubMed ID: 35371310

Doi: 10.7150/jca.65543

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A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination

Authors: Sarah F Andrews, Julie E Raab, Jason Gorman, Rebecca A Gillespie, Crystal S F Cheung, Reda Rawi, Lauren Y Cominsky, Jeffrey C Boyington, Adrian Creanga, Chen-Hsiang Shen, Darcy R Harris, Adam S Olia, Alexandra F Nazzari, Tongqing Zhou, Katherine V Houser, Grace L Chen, John R Mascola, Barney S Graham, Masaru Kanekiyo, Julie E Ledgerwood, Peter D Kwong, Adrian B McDermott

Journal: Nat Med

PubMed ID: 35115707

Doi: 10.1038/s41591-021-01636-8

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Characterization and Interaction Analysis of the Secondary Cell Wall Synthesis-Related Transcription Factor in Lamb

Authors: Peizhen Chen, Rong Li, Lingzhi Zhu, Qingqing Hao, Sheng Yao, Jiahe Liu, Kongshu Ji

Journal: Int J Mol Sci

PubMed ID: 35216196

Doi: 10.3390/ijms23042079

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Unresolved stalled ribosome complexes restrict cell-cycle progression after genotoxic stress

Authors: Mark Stoneley, Robert F Harvey, Thomas E Mulroney, Ryan Mordue, Rebekah Jukes-Jones, Kelvin Cain, Kathryn S Lilley, Ritwick Sawarkar, Anne E Willis

Journal: Mol Cell

PubMed ID: 35180429

Doi: 10.1016/j.molcel.2022.01.019

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Non-clinical immunogenicity, biodistribution and toxicology evaluation of a chimpanzee adenovirus-based COVID-19 vaccine in rat and rhesus macaque

Authors: Xuedong Dai, Weijun Zhao, Xin Tong, Wei Liu, Xianhuan Zeng, Xiaohui Duan, Hua Wu, Lili Wang, Zhen Huang, Xinying Tang, Yong Yang

Journal: Arch Toxicol

PubMed ID: 35226134

Doi: 10.1007/s00204-021-03221-x

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Deleterious variants in CRLS1 lead to cardiolipin deficiency and cause an autosomal recessive multi-system mitochondrial disease

Authors: Richard G Lee, Shanti Balasubramaniam, Maike Stentenbach, Tom Kralj, Timothy McCubbin, Benjamin Padman, Janine Smith, Lisa G Riley, Archana Priyadarshi, Liuyu Peng, Madison R Nuske, Richard Webster, Ken Peacock, Philip Roberts, Zornitza Stark, Gabrielle Lemire, Yoko A Ito, Kym M Boycott, Michael T Geraghty, Jan Bert Klinken, Sacha Ferdinandusse, Ying Zhou, Rebecca Walsh, Esteban Marcellin, David R Thorburn, Tony Rosciolli, Janice Fletcher, Oliver Rackham, Frédéric M Vaz, Gavin E Reid, Aleksandra Filipovska

Journal: Hum Mol Genet

PubMed ID: 35147173

Doi: 10.1093/hmg/ddac040

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Functional characterization of tyrosine decarboxylase genes that contribute to acteoside biosynthesis in Rehmannia glutinosa

Authors: Yan Hui Yang, Mu Rong Yang, Jian Yu Zhu, Ke Wei Dong, Yan Jie Yi, Rui Fang Li, Lei Zeng, Chang Fu Zhang

Journal: Planta

PubMed ID: 35147783

Doi: 10.1007/s00425-022-03849-8

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Genome-wide identification and characterization of AINTEGUMENTA-LIKE (AIL) family genes in apple (Malus domestica Borkh)

Authors: Xiaolei Han, Kai Liu, Gaopeng Yuan, Shanshan He, Peihua Cong, Caixia Zhang

Journal: Genomics

PubMed ID: 35151838

Doi: 10.1016/j.ygeno.2022.110313

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Discovery and Mechanism of Small Molecule Inhibitors Selective for the Chromatin-Binding Domains of Oncogenic UHRF1

Authors: Wallace H Liu, Robert E Miner, Brittany N Albaugh, Gene E Ananiev, Scott A Wildman, John M Denu

Journal: Biochemistry

PubMed ID: 35143176

Doi: 10.1021/acs.biochem.1c00698

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Tetrahymena thermophila granule lattice protein 3 improves solubility of sexual stage malaria antigens expressed in Escherichia coli

Authors: Cengiz Akkale, Donna Marie Cassidy-Hanley, Theodore G Clark

Journal: Protein Expr Purif

PubMed ID: 35134517

Doi: 10.1016/j.pep.2022.106060

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Immunoaffinity monoliths for multiplexed extraction of preterm birth biomarkers from human blood serum in 3D printed microfluidic devices

Authors: Haifa M Almughamsi, Makella K Howell, Samuel R Parry, Joule E Esene, Jacob B Nielsen, Gregory P Nordin, Adam T Woolley

Journal: Analyst

PubMed ID: 35103723

Doi: 10.1039/d1an01365c

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High-throughput split-protein profiling by combining transposon mutagenesis and regulated protein-protein interactions with deep sequencing

Authors: Kai Zhou, Thomas Litfin, Md Solayman, Huijun Zhao, Yaoqi Zhou, Jian Zhan

Journal: Int J Biol Macromol

PubMed ID: 35120933

Doi: 10.1016/j.ijbiomac.2022.01.173

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Inhibition of the Interaction of TREM-1 and eCIRP Attenuates Inflammation and Improves Survival in Hepatic Ischemia/Reperfusion

Authors: Timothy Borjas, Asha Jacob, HaoTing Yen, Vihas Patel, Gene F Coppa, Monowar Aziz, Ping Wang

Journal: Shock

PubMed ID: 34864782

Doi: 10.1097/SHK.0000000000001894

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RNA modifications stabilize the tertiary structure of tRNAfMet by locally increasing conformational dynamics

Authors: Thomas Biedenbänder, Vanessa de Jesus, Martina Schmidt-Dengler, Mark Helm, Björn Corzilius, Boris Fürtig

Journal: Nucleic Acids Res

PubMed ID: 35137185

Doi: 10.1093/nar/gkac040

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PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation

Authors: Prasidda Khadka, Zachary J Reitman, Sophie Lu, Graham Buchan, Gabrielle Gionet, Frank Dubois, Diana M Carvalho, Juliann Shih, Shu Zhang, Noah F Greenwald, Travis Zack, Ofer Shapira, Kristine Pelton, Rachel Hartley, Heather Bear, Yohanna Georgis, Spandana Jarmale, Randy Melanson, Kevin Bonanno, Kathleen Schoolcraft, Peter G Miller, Alexandra L Condurat, Elizabeth M Gonzalez, Kenin Qian, Eric Morin, Jaldeep Langhnoja, Leslie E Lupien, Veronica Rendo, Jeromy Digiacomo, Dayle Wang, Kevin Zhou, Rushil Kumbhani, Maria E Guerra Garcia, Claire E Sinai, Sarah Becker, Rachel Schneider, Jayne Vogelzang, Karsten Krug, Amy Goodale, Tanaz Abid, Zohra Kalani, Federica Piccioni, Rameen Beroukhim, Nicole S Persky, David E Root, Angel M Carcaboso, Benjamin L Ebert, Christine Fuller, Ozgun Babur, Mark W Kieran, Chris Jones, Hasmik Keshishian, Keith L Ligon, Steven A Carr, Timothy N Phoenix, Pratiti Bandopadhayay

Journal: Nat Commun

PubMed ID: 35105861

Doi: 10.1038/s41467-022-28198-8

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Non-ionic detergent assists formation of supercharged nanodiscs and insertion of membrane proteins

Authors: Frederik G Tidemand, Sara Blemmer, Nicolai T Johansen, Lise Arleth, Martin Cramer Pedersen

Journal: Biochim Biophys Acta Biomembr

PubMed ID: 35182589

Doi: 10.1016/j.bbamem.2022.183884

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A Novel CD3/BCMA Bispecific T-cell Redirecting Antibody for the Treatment of Multiple Myeloma

Authors: Mengshang Xiong, Ruoqi Liu, Xiaomin Lei, Dongmei Fan, Fangzhen Lin, Wei Hao, Xiangfei Yuan, Yuanyuan Yang, Xiaolong Zhang, Zhou Ye, Yang Lu, Yanjun Zhang, Jianxiang Wang, Dongsheng Xiong

Journal: J Immunother

PubMed ID: 34711791

Doi: 10.1097/CJI.0000000000000401

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LncRNA NORAD Mediates the Proliferation and Apoptosis of Diffuse Large-B-Cell Lymphoma via Regulation of miR-345-3p/TRAF6 Axis

Authors: Yang Li, Yuanyuan Lv, Jiangya Wang, Xiuli Zhu, Jian Chen, Wenting Zhang, Chuan Wang, Lian Jiang

Journal: Arch Med Res

PubMed ID: 35164979

Doi: 10.1016/j.arcmed.2022.01.004

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A genome-wide CRISPR screen identifies HuR as a regulator of apoptosis induced by dsRNA and virus

Authors: Huixin Gao, Yuxia Lin, Changbai Huang, Xiaobo Li, Michael S Diamond, Chao Liu, Rong Zhang, Ping Zhang

Journal: J Cell Sci

PubMed ID: 35112703

Doi: 10.1242/jcs.258855

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TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A

Authors: X Rosa Ma, Mercedes Prudencio, Yuka Koike, Sarat C Vatsavayai, Garam Kim, Fred Harbinski, Adam Briner, Caitlin M Rodriguez, Caiwei Guo, Tetsuya Akiyama, H Broder Schmidt, Beryl B Cummings, David W Wyatt, Katherine Kurylo, Georgiana Miller, Shila Mekhoubad, Nathan Sallee, Gemechu Mekonnen, Laura Ganser, Jack D Rubien, Karen Jansen-West, Casey N Cook, Sarah Pickles, Björn Oskarsson, Neill R Graff-Radford, Bradley F Boeve, David S Knopman, Ronald C Petersen, Dennis W Dickson, James Shorter, Sua Myong, Eric M Green, William W Seeley, Leonard Petrucelli, Aaron D Gitler

Journal: Nature

PubMed ID: 35197626

Doi: 10.1038/s41586-022-04424-7

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In vivo mRNA delivery to virus-specific T cells by light-induced ligand exchange of MHC class I antigen-presenting nanoparticles

Authors: Fang-Yi Su, Qingyang Henry Zhao, Shreyas N Dahotre, Lena Gamboa, Swapnil Subhash Bawage, Aaron D Silva Trenkle, Ali Zamat, Hathaichanok Phuengkham, Rafi Ahmed, Philip J Santangelo, Gabriel A Kwong

Journal: Sci Adv

PubMed ID: 35196075

Doi: 10.1126/sciadv.abm7950

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A Triple Gene-Deleted Pseudorabies Virus-Vectored Subunit PCV2b and CSFV Vaccine Protects Pigs against PCV2b Challenge and Induces Serum Neutralizing Antibody Response against CSFV

Authors: Selvaraj Pavulraj, Katrin Pannhorst, Rhett W Stout, Daniel B Paulsen, Mariano Carossino, Denise Meyer, Paul Becher, Shafiqul I Chowdhury

Journal: Vaccines (Basel)

PubMed ID: 35214763

Doi: 10.3390/vaccines10020305

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Selective Detection of Serogroup 1 and 5 with a Digital Photocorrosion Biosensor Using Antimicrobial Peptide-Antibody Sandwich Strategy

Authors: M Amirul Islam, Walid M Hassen, Ishika Ishika, Azam F Tayabali, Jan J Dubowski

Journal: Biosensors (Basel)

PubMed ID: 35200365

Doi: 10.3390/bios12020105

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CD19-targeted BiTE expression by an oncolytic vaccinia virus significantly augments therapeutic efficacy against B-cell lymphoma

Authors: Wen Lei, Qian Ye, Yuanyuan Hao, Jie Chen, Yu Huang, Liu Yang, Shibing Wang, Wenbin Qian

Journal: Blood Cancer J

PubMed ID: 35228544

Doi: 10.1038/s41408-022-00634-4

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Distribution of non-synonymous Vkorc1 mutations in roof rats (Rattus rattus) in France and in Spain - consequences for management

Authors: Marlène Damin-Pernik, Abdessalem Hammed, Ludivine Giraud, Joffrey Goulois, Etienne Benoît, Virginie Lattard

Journal: Pestic Biochem Physiol

PubMed ID: 35430058

Doi: 10.1016/j.pestbp.2022.105052

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DNA Vaccines Expressing the Envelope and Membrane Proteins Provide Partial Protection Against SARS-CoV-2 in Mice

Authors: Jinni Chen, Yao Deng, Baoying Huang, Di Han, Wen Wang, Mengjing Huang, Chengcheng Zhai, Zhimin Zhao, Ren Yang, Ying Zhao, Wenling Wang, Desheng Zhai, Wenjie Tan

Journal: Front Immunol

PubMed ID: 35281016

Doi: 10.3389/fimmu.2022.827605

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