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Monoallelic de novo AJAP1 loss-of-function variants disrupt trans-synaptic control of neurotransmitter release

Authors: Simon Fr h; Sami Boudkkazi; Peter Koppensteiner; Vita Sereikaite; Li-Yuan Chen; Diego Fernandez-Fernandez; Pascal D. Rem; Daniel Ulrich; Jochen Schwenk; Ziyang Chen; Elodie Le Monnier; Thorsten Fritzius; Sabrina M. Innocenti; Val rie Besseyrias; Luca Trov ; Michal Stawarski; Emanuela Argilli; Elliott H. Sherr; Bregje van Bon; Erik-Jan Kamsteeg; Maria Iascone; Alba Pilotta; Maria R. Cutr ; Mahshid S. Azamian; Andr s Hern ndez-Garc a; Seema R. Lalani; Jill A. Rosenfeld; Xiaonan Zhao; Tiphanie P. Vogel; Herda Ona; Daryl A. Scott; Peter Scheiffele; Kristian Str mgaard; Mehdi Tafti; Martin Gassmann; Bernd Fakler; Ryuichi Shigemoto; Bernhard Bettler

Journal: SCIENCE ADVANCES

PubMed ID: 38985877

Doi: 10.1126/sciadv.adk5462

Products & Services: Gene Fragments

Selection of Brucella abortus mimetic epitopes for fast diagnostic purposes in cattle

Authors: Fabiana de Almeida Araújo Santos, Patrícia Tiemi Fujimura, Emília Rezende Vaz, Ana Cristina Honorato de Castro, Ana Graci Brito-Madurro, Vivian Alonso-Goulart, Luciana Machado Bastos, Belchiolina Beatriz Fonseca, Anna Monteiro Correia Lima, Luiz Ricardo Goulart

Journal: Vet Res Commun

PubMed ID: 36445603

Doi: 10.1007/s11259-022-10043-4

Products & Services: Peptide Synthesis

Detection of concentration-dependent conformational changes in SARS-CoV-2 nucleoprotein by agarose native gel electrophoresis

Authors: Ryo Sato, Yui Tomioka, Chiaki Sakuma, Masataka Nakagawa, Yasunori Kurosawa, Kohei Shiba, Tsutomu Arakawa, Teruo Akuta

Journal: Anal Biochem

PubMed ID: 36427555

Doi: 10.1016/j.ab.2022.114995

Products & Services: Molecular Biology Reagents

Structures of trehalose-6-phosphate synthase, Tps1, from the fungal pathogen Cryptococcus neoformans : A target for antifungals

Authors: Erica J. Washington; Ye Zhou; Allen L. Hsu; Matthew Petrovich; Jennifer L. Tenor; Dena L. Toffaletti; Ziqiang Guan; John R. Perfect; Mario J. Borgnia; Alberto Bartesaghi; Richard G. Brennan

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 39083421

Doi: 10.1073/pnas.2314087121

Estrogen receptor β activation inhibits colitis by promoting NLRP6-mediated autophagy

Authors: Wentao Fan, Chenchen Ding, Shuhui Liu, Xiaona Gao, Xiaofei Shen, Marthe De Boevre, Zhangshan Gao, Mengcong Li, Shuo Zhang, Yufan Miao, Wenxian Guan, Guangliang Liu, Liping Yan, Sarah De Saeger, Suquan Song

Journal: Cell Rep

PubMed ID: 36223738

Doi: 10.1016/j.celrep.2022.111454

Products & Services: Protein and Antibody Isolation

Duration of antiretroviral therapy impacts the degree of residual SIV infection in the gut in long-term non-progressing Chinese rhesus macaques

Authors: Antonio Solis-Leal, Ann-Marie May, Mahesh Mohan, Jason P Dufour, Binhua Ling

Journal: J Med Virol

PubMed ID: 36181356

Doi: 10.1002/jmv.28185

Products & Services: Protein and Antibody Isolation

Recombinant acetylxylan esterase of Halalkalibacterium halodurans NAH-Egypt: molecular and biochemical study.

Authors: Amira M Embaby , Hoda E Mahmoud

Journal: AMB Express .

PubMed ID: 36289146

Doi: A10.1186/s13568-022-01476-w.

Products & Services: PCR Cloning and Subcloning Custom Vector Construction

PD-L1/TLR7 dual-targeting nanobody-drug conjugate mediates potent tumor regression via elevating tumor immunogenicity in a host-expressed PDL1 bias-dependent way

Authors: Xiaolu Yu, Yiru Long , Binfan Chen , Yongliang Tong , Mengwen Shan , Xiaomin Jia , Chao Hu , Meng Liu , Ji Zhou , Feng Tang , Henglei Lu , Runqiu Chen , Pan Xu , Wei Huang , Jin Ren , Yakun Wan , Jianhua Sun , Jia Li , Guangyi Jin , Likun Gong

Journal: J Immunother Cancer .

PubMed ID: 36253000

Doi: 10.1136/jitc-2022-004590

Products & Services: Recombinant Proteins

Hydrogen-bonds mediate liquid-liquid phase separation of mussel derived adhesive peptides

Authors: Qi Guo, Guijin Zou, Xuliang Qian, Shujun Chen, Huajian Gao, Jing Yu

Journal: Nat Commun

PubMed ID: 36182948

Doi: 10.1038/s41467-022-33545-w

Products & Services: Catalog Peptides

An experimental test of the nicotinic hypothesis of COVID-19

Authors: Nicole E Godellas, Gisela D Cymes, Claudio Grosman

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36279466

Doi: 10.1073/pnas.2204242119

Products & Services: Catalog Peptides