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An antibody from single human V-rearranging mouse neutralizes all SARS-CoV-2 variants through BA5 by inhibiting membrane fusion

Authors: Sai Luo, Jun Zhang, Alex J B Kreutzberger, Amanda Eaton, Robert J Edwards, Changbin Jing, Hai-Qiang Dai, Gregory D Sempowski, Kenneth Cronin, Robert Parks, Adam Yongxin Ye, Katayoun Mansouri, Maggie Barr, Novalia Pishesha, Aimee Chapdelaine Williams, Lucas Vieira Francisco, Anand Saminathan, Hanqin Peng, Himanshu Batra, Lorenza Bellusci, Surender Khurana, S Munir Alam, David C Montefiori, Kevin O Saunders, Ming Tian, Hidde Ploegh, Tom Kirchhausen, Bing Chen, Barton F Haynes, Frederick W Alt

Journal: Sci Immunol

PubMed ID: 35951767

Doi: 10.1126/sciimmunol.add5446

Products & Services: Monoclonal Antibody Services Peptide Synthesis

TCR extracellular domain genetically linked to CD28, 2B4/41BB and DAP10/CD3ζ -engineered NK cells mediates antitumor effects

Authors: Shance Li, Chaoting Zhang, Luyan Shen, Xia Teng, Yefei Xiao, Bentong Yu, Zheming Lu

Journal: Cancer Immunol Immunother

PubMed ID: 35988132

Doi: 10.1007/s00262-022-03275-5

Products & Services: Custom Vector Construction

Structure and engineering of the minimal type VI CRISPR-Cas13bt3

Authors: Ryoya Nakagawa, Soumya Kannan, Han Altae-Tran, Satoru N Takeda, Atsuhiro Tomita, Hisato Hirano, Tsukasa Kusakizako, Tomohiro Nishizawa, Keitaro Yamashita, Feng Zhang, Hiroshi Nishimasu, Osamu Nureki

Journal: Mol Cell

PubMed ID: 36027912

Doi: 10.1016/j.molcel.2022.08.001

Products & Services: Synthetic Guide RNA

Impact of SARS-CoV-2 Spike Mutations on Its Activation by TMPRSS2 and the Alternative TMPRSS13 Protease

Authors: Annelies Stevaert, Ria Van Berwaer, Cato Mestdagh, Julie Vandeput, Els Vanstreels, Valerie Raeymaekers, Manon Laporte, Lieve Naesens

Journal: MBio

PubMed ID: 35913162

Doi: 10.1128/mbio.01376-22

Products & Services: Protein and Antibody Isolation

SARS-CoV-2 in a Mink Farm in Italy: Case Description, Molecular and Serological Diagnosis by Comparing Different Tests

Authors: Ana Moreno, Davide Lelli, Tiziana Trogu, Antonio Lavazza, Ilaria Barbieri, MariaBeatrice Boniotti, Giulia Pezzoni, Cristian Salogni, Stefano Giovannini, Giovanni Alborali, Silvia Bellini, Massimo Boldini, Marco Farioli, Luigi Ruocco, Olivia Bessi, Andrea Maroni Ponti, Ilaria Di Bartolo, Luca De Sabato, Gabriele Vaccari, Gabriele Belli, Alberto Margutti, Maurilio Giorgi

Journal: Viruses

PubMed ID: 36016360

Doi: 10.3390/v14081738

Products & Services: Recombinant Proteins

Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody

Authors: Mithu Baidya, Madhu Chaturvedi, Hemlata Dwivedi-Agnihotri, Ashutosh Ranjan, Dominic Devost, Yoon Namkung, Tomasz Maciej Stepniewski, Shubhi Pandey, Minakshi Baruah, Bhanupriya Panigrahi, Parishmita Sarma, Manish K Yadav, Jagannath Maharana, Ramanuj Banerjee, Kouki Kawakami, Asuka Inoue, Jana Selent, Stéphane A Laporte, Terence E Hébert, Arun K Shukla

Journal: Nat Commun

PubMed ID: 35941121

Doi: 10.1038/s41467-022-32386-x

Products & Services: Peptide Synthesis

Microfluidic-Derived Detection of Protein-Facilitated Copper Flux Across Lipid Membranes

Authors: Kamil Górecki, Jesper S Hansen, Ping Li, Niloofar Nayeri, Karin Lindkvist-Petersson, Pontus Gourdon

Journal: Anal Chem

PubMed ID: 35969432

Doi: 10.1021/acs.analchem.2c02081

Products & Services: Bacterial Expression

Water-organizing motif continuity is critical for potent ice nucleation protein activity

Authors: Jordan Forbes, Akalabya Bissoyi, Lukas Eickhoff, Naama Reicher, Thomas Hansen, Christopher G Bon, Virginia K Walker, Thomas Koop, Yinon Rudich, Ido Braslavsky, Peter L Davies

Journal: Nat Commun

PubMed ID: 36028506

Doi: 10.1038/s41467-022-32469-9

Products & Services: DNA Sequencing

Second-Generation SuptoxR Strains for High-Level Recombinant Membrane Protein Production

Authors: Eleni Vasilopoulou, Artemis Giannakopoulou, Charalampos Kapsalis, Myrsini Michou, Aristeidis Michoglou-Sergiou, Fragiskos N Kolisis, Georgios Skretas

Journal: ACS Synth Biol

PubMed ID: 35922033

Doi: 10.1021/acssynbio.1c00598

Products & Services: Custom Vector Construction

TROP2 Down-regulated DSG2 to Promote Gastric Cancer Cell Invasion and Migration by EGFR/AKT and DSG2/PG/β-Catenin Pathways

Authors: Tingting Yang, Lizhou Jia, Susu Bian, Xinxia Chang, Qian Zhang, Qi Tang, Jing Zhu, Zhiping Yang, Zhenqing Feng

Journal: Curr Cancer Drug Targets

PubMed ID: 35392784

Doi: 10.2174/1568009622666220407111013

Products & Services: Protein and Antibody Isolation