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Ubiquitination at the lysine 27 residue of the Parkin ubiquitin-like domain is suggestive of a new mechanism of Parkin activation

Authors: Jun-Yi Liu, Tsuyoshi Inoshita, Kahori Shiba-Fukushima, Shigeharu Yoshida, Kosuke Ogata, Yasushi Ishihama, Yuzuru Imai, Nobutaka Hattori

Journal: Hum Mol Genet

PubMed ID: 35313349

Doi: 10.1093/hmg/ddac064

Products & Services: Mutagenesis Services

Neuroprotection of Bone Marrow-Derived Mesenchymal Stem Cell-Derived Extracellular Vesicle-Enclosed miR-410 Correlates with HDAC4 Knockdown in Hypoxic-Ischemic Brain Damage

Authors: Mingqi Shen, Rongxiu Zheng, Xuan Kan

Journal: Neurochem Res

PubMed ID: 36028735

Doi: 10.1007/s11064-022-03670-5

Products & Services: Mutant Libraries

Pathway elucidation of bioactive rhamnosylated ginsenosides in Panax ginseng and their de novo high-level production by engineered Saccharomyces cerevisiae

Authors: Chaojing Li, Xing Yan, Zhenzhen Xu, Yan Wang, Xiao Shen, Lei Zhang, Zhihua Zhou, Pingping Wang

Journal: Commun Biol

PubMed ID: 35918414

Doi: 10.1038/s42003-022-03740-y

Products & Services: Codon Optimization

Identification of the extracellular metallo-endopeptidases ADAM and ADAMTS in the yellow fever mosquito Aedes aegypti

Authors: Christie S Herd, Xiudao Yu, Yingjun Cui, Alexander W E Franz

Journal: Insect Biochem Mol Biol

PubMed ID: 35932972

Doi: 10.1016/j.ibmb.2022.103815

Products & Services: Polyclonal Antibody Services

Development of a pentavalent broadly protective nucleoside-modified mRNA vaccine against influenza B viruses

Authors: Norbert Pardi, Juan Manuel Carreño, George O'Dell, Jessica Tan, Csaba Bajusz, Hiromi Muramatsu, Willemijn Rijnink, Shirin Strohmeier, Madhumathi Loganathan, Dominika Bielak, Molly M H Sung, Ying K Tam, Florian Krammer, Meagan McMahon

Journal: Nat Commun

PubMed ID: 35945226

Doi: 10.1038/s41467-022-32149-8

Products & Services: Gene Synthesis

Identification, molecular and biochemical characterization of a novel thermoactive and thermostable glucoamylase from Thermoanaerobacter ethanolicus

Authors: Natael M Wayllace, Nicolas Hedín, María V Busi, Diego F Gomez-Casati

Journal: Biotechnol Lett

PubMed ID: 35997915

Doi: 10.1007/s10529-022-03296-1

Products & Services: Codon Optimization

Microfluidic-Derived Detection of Protein-Facilitated Copper Flux Across Lipid Membranes

Authors: Kamil Górecki, Jesper S Hansen, Ping Li, Niloofar Nayeri, Karin Lindkvist-Petersson, Pontus Gourdon

Journal: Anal Chem

PubMed ID: 35969432

Doi: 10.1021/acs.analchem.2c02081

Products & Services: Bacterial Expression

Reduced sister chromatid cohesion acts as a tumor penetrance modifier

Authors: Jun Wang, Holly R Thomas, Yu Chen, Stefanie M Percival, Stephanie C Waldrep, Ryne C Ramaker, Robert G Thompson, Sara J Cooper, Zechen Chong, John M Parant

Journal: PLoS Genet

PubMed ID: 35994499

Doi: 10.1371/journal.pgen.1010341

Products & Services: Gene Synthesis

Novel Hits for N-Myristoyltransferase Inhibition Discovered by Docking-Based Screening

Authors: Danislav S Spassov, Mariyana Atanasova, Irini Doytchinova

Journal: Molecules

PubMed ID: 36080246

Doi: 10.3390/molecules27175478

Products & Services: Catalog Peptides

Water-organizing motif continuity is critical for potent ice nucleation protein activity

Authors: Jordan Forbes, Akalabya Bissoyi, Lukas Eickhoff, Naama Reicher, Thomas Hansen, Christopher G Bon, Virginia K Walker, Thomas Koop, Yinon Rudich, Ido Braslavsky, Peter L Davies

Journal: Nat Commun

PubMed ID: 36028506

Doi: 10.1038/s41467-022-32469-9

Products & Services: DNA Sequencing