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Long noncoding RNA-mediated activation of PROTOR1/PRR5-AKT signaling shunt downstream of PI3K in triple-negative breast cancer

Authors: Zhenbo Tu, Yi Hu, Devesh Raizada, Mahmoud A Bassal, Daniel G Tenen, Antoine E Karnoub

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36269860

Doi: 10.1073/pnas.2203180119

Products & Services: Mammalian Expression

AlphaFold version 20 elucidates the binding mechanism between VIPR2 and KS-133, and reveals an S-S bond (Cys-Cys) formation of functional significance for VIPR2

Authors: Kotaro Sakamoto, Satoshi Asano, Yukio Ago, Takatsugu Hirokawa

Journal: Biochem Biophys Res Commun

PubMed ID: 36332470

Doi: 10.1016/j.bbrc.2022.10.071

Products & Services: Plasmid DNA Preparation

Presence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibodies Among Vietnamese Healthcare Workers by Dosing Interval for ChAdOx1 nCoV-19 Vaccine

Authors: Dien M Vu, Diep T B Vu, Thuy T T Do, Allison E Olmsted, Bach H Dao, Truc T Thai, Chi L Nguyen, Nhung T T Le, Tuan A Le, Hien T T Bui, Thach N Pham, Matthew R Moore

Journal: Clin Infect Dis

PubMed ID: 35723271

Doi: 10.1093/cid/ciac493

Products & Services: Recombinant Proteins

Identification of Cysteine 270 as a Novel Site for Allosteric Modulators of SARS-CoV-2 Papain-Like Protease

Authors: Hangchen Hu, Qian Wang, Haixia Su, Qiang Shao, Wenfeng Zhao, Guofeng Chen, Minjun Li, Yechun Xu

Journal: Angew Chem Int Ed Engl

PubMed ID: 36308706

Doi: 10.1002/anie.202212378

Products & Services: Codon Optimization

TBC1D18 is a Rab5-GAP that coordinates endosome maturation together with Mon1

Authors: Shu Hiragi, Takahide Matsui, Yuriko Sakamaki, Mitsunori Fukuda

Journal: J Cell Biol

PubMed ID: 36197338

Doi: 10.1083/jcb.202201114

Products & Services: Protein and Antibody Isolation

The diurnal emission of floral scent in Oncidium hybrid orchid is controlled by CIRCADIAN CLOCK ASSOCIATED 1 (CCA1) through the direct regulation on terpene synthase

Authors: Chao-Wei Yeh, Hui-Qin Zhong, Yung-Feng Ho, Zhi-Hong Tian, Kai-Wun Yeh

Journal: BMC Plant Biol

PubMed ID: 36195835

Doi: 10.1186/s12870-022-03850-z

Products & Services: Protein and Antibody Isolation

Recombinant acetylxylan esterase of Halalkalibacterium halodurans NAH-Egypt: molecular and biochemical study.

Authors: Amira M Embaby , Hoda E Mahmoud

Journal: AMB Express .

PubMed ID: 36289146

Doi: A10.1186/s13568-022-01476-w.

Products & Services: PCR Cloning and Subcloning Custom Vector Construction

PD-L1/TLR7 dual-targeting nanobody-drug conjugate mediates potent tumor regression via elevating tumor immunogenicity in a host-expressed PDL1 bias-dependent way

Authors: Xiaolu Yu, Yiru Long , Binfan Chen , Yongliang Tong , Mengwen Shan , Xiaomin Jia , Chao Hu , Meng Liu , Ji Zhou , Feng Tang , Henglei Lu , Runqiu Chen , Pan Xu , Wei Huang , Jin Ren , Yakun Wan , Jianhua Sun , Jia Li , Guangyi Jin , Likun Gong

Journal: J Immunother Cancer .

PubMed ID: 36253000

Doi: 10.1136/jitc-2022-004590

Products & Services: Recombinant Proteins

A novel site on dual-specificity phosphatase MKP7/DUSP16 is required for catalysis and MAPK binding

Authors: Shanelle Shillingford, Lei Zhang, Yulia Surovtseva, Sam Dorry, Elias Lolis, Anton M Bennett

Journal: J Biol Chem

PubMed ID: 36272649

Doi: 10.1016/j.jbc.2022.102617

Products & Services: Mutagenesis Services

SCF regulates G2-M progression through control of CCNL1 ubiquitination

Authors: Siobhan O'Brien, Susan Kelso, Zachary Steinhart, Stephen Orlicky, Monika Mis, Yunhye Kim, Sichun Lin, Frank Sicheri, Stephane Angers

Journal: EMBO Rep

PubMed ID: 36278408

Doi: 10.15252/embr.202255044

Products & Services: Catalog Peptides