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A plant immune protein enables broad antitumor response by rescuing microRNA deficiency

Authors: Ye Qi , Li Ding , Siwen Zhang , Shengze Yao , Jennie Ong , Yi Li , Hong Wu , Peng Du

Journal: Cell

PubMed ID: 35623329

Doi: 10.1016/j.cell.2022.04.030

Products & Services: Protein Electrophoresis and Western

Salt-inducible kinase 3 protects tumor cells from cytotoxic T-cell attack by promoting TNF-induced NF-κB activation

Authors: Antonio Sorrentino, Ayse Nur Menevse, Tillmann Michels, Valentina Volpin, Franziska Christine Durst, Julian Sax, Maria Xydia, Abir Hussein, Slava Stamova, Steffen Spoerl, Nicole Heuschneider, Jasmin Muehlbauer, Katharina Marlene Jeltsch, Anchana Rathinasamy, Melanie Werner-Klein, Marco Breinig, Damian Mikietyn, Christian Kohler, Isabel Poschke, Sabrina Purr, Olivia Reidell, Catarina Martins Freire, Rienk Offringa, Claudia Gebhard, Rainer Spang, Michael Rehli, Michael Boutros, Christian Schmidl, Nisit Khandelwal, Philipp Beckhove

Journal: J Immunother Cancer

PubMed ID: 35606086

Doi: 10.1136/jitc-2021-004258

Products & Services: Plasmid DNA Preparation

SARS-CoV-2-mRNA Booster Vaccination Reverses Non-Responsiveness and Early Antibody Waning in Immunocompromised Patients - A Phase Four Study Comparing Immune Responses in Patients With Solid Cancers, Multiple Myeloma and Inflammatory Bowel Disease

Authors: Angelika Wagner, Erika Garner-Spitzer, Anna-Margarita Schötta, Maria Orola, Andrea Wessely, Ines Zwazl, Anna Ohradanova-Repic, Lukas Weseslindtner, Gabor Tajti, Laura Gebetsberger, Bernhard Kratzer, Elena Tomosel, Maximilian Kutschera, Selma Tobudic, Winfried F Pickl, Michael Kundi, Hannes Stockinger, Gottfried Novacek, Walter Reinisch, Christoph Zielinski, Ursula Wiedermann

Journal: Front Immunol

PubMed ID: 35634285

Doi: 10.3389/fimmu.2022.889138

Disordered Regions Flanking the Binding Interface Modulate Affinity between CBP and NCOA

Authors: Elin Karlsson, Jan Schnatwinkel, Cristina Paissoni, Eva Andersson, Christian Herrmann, Carlo Camilloni, Per Jemth

Journal: J Mol Biol

PubMed ID: 35605677

Doi: 10.1016/j.jmb.2022.167643

Products & Services: Plasmid DNA Preparation

A nucleotide-sensing oligomerization mechanism that controls NrdR-dependent transcription of ribonucleotide reductases

Authors: Inna Rozman Grinberg, Markel Martínez-Carranza, Ornella Bimai, Ghada Nouaïria, Saher Shahid, Daniel Lundin, Derek T Logan, Britt-Marie Sjöberg, Pål Stenmark

Journal: Nat Commun

PubMed ID: 35577776

Doi: 10.1038/s41467-022-30328-1

Products & Services: Custom DNA/RNA Oligos

Safety and immunogenicity of an egg-based inactivated Newcastle disease virus vaccine expressing SARS-CoV-2 spike: Interim results of a randomized, placebo-controlled, phase 1/2 trial in Vietnam

Authors: Anh Duc Dang, Thiem Dinh Vu, Ha Hai Vu, Van Thanh Ta, Anh Thi Van Pham, Mai Thi Ngoc Dang, Be Van Le, Thai Huu Duong, Duoc Van Nguyen, Saranath Lawpoolsri, Pailinrut Chinwangso, Jason S McLellan, Ching-Lin Hsieh, Adolfo Garcia-Sastre, Peter Palese, Weina Sun, Jose L Martinez, Irene Gonzalez-Dominguez, Stefan Slamanig, Juan Manuel Carreño, Johnstone Tcheou, Florian Krammer, Ariel Raskin, Huong Minh Vu, Thang Cong Tran, Huong Mai Nguyen, Laina D Mercer, Rama Raghunandan, Manjari Lal, Jessica A White, Richard Hjorth, Bruce L Innis, Rami Scharf

Journal: Vaccine

PubMed ID: 35577631

Doi: 10.1016/j.vaccine.2022.04.078

Products & Services: Mammalian Expression

Class III Peroxidases PRX01, PRX44, and PRX73 Control Root Hair Growth in

Authors: Eliana Marzol, Cecilia Borassi, Mariana Carignani Sardoy, Philippe Ranocha, Ariel A Aptekmann, Mauro Bringas, Janice Pennington, Julio Paez-Valencia, Javier Martínez Pacheco, Diana R Rodríguez-Garcia, Yossmayer Del Carmen Rondón Guerrero, Juan Manuel Peralta, Margaret Fleming, John W Mishler-Elmore, Silvina Mangano, Francisca Blanco-Herrera, Patricia A Bedinger, Christophe Dunand, Luciana Capece, Alejandro D Nadra, Michael Held, Marisa S Otegui, José M Estevez

Journal: Int J Mol Sci

PubMed ID: 35628189

Doi: 10.3390/ijms23105375

Products & Services: Plasmid DNA Preparation

Correction: The arginine deaminase system plays distinct roles in Borrelia burgdorferi and Borrelia hermsii

Authors: Crystal L Richards, Sandra J Raffel, Sébastien Bontemps-Gallo, Daniel P Dulebohn, Tessa C Herbert, Frank C Gherardini

Journal: PLoS Pathog

PubMed ID: 35536845

Doi: 10.1371/journal.ppat.1010549

Products & Services: Protein and Antibody Isolation

Low specific growth rate and temperature in fed-batch cultures of a beta-propeller phytase producing Pichia pastoris strain under GAP promoter trigger increased KAR2 and PSA1-1 gene expression yielding enhanced extracellular productivity

Authors: Ana Lucía Herrera-Estala, José Antonio Fuentes-Garibay, Martha Guerrero-Olazarán, José María Viader-Salvadó

Journal: J Biotechnol

PubMed ID: 35618082

Doi: 10.1016/j.jbiotec.2022.05.010

Products & Services: Gene Fragments

Enzymatically amplified linear dbDNA as a rapid and scalable solution to industrial lentiviral vector manufacturing

Authors: Maria Barreira, Claire Kerridge, Sara Jorda, Didrik Olofsson, Alexander Neumann, Helen Horton, Sarah Smith-Moore

Journal: Gene Ther

PubMed ID: 35606492

Doi: 10.1038/s41434-022-00343-4

Products & Services: Gene Synthesis