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Adverse effects following anti-COVID-19 vaccination with mRNA-based BNT162b2 are alleviated by altering the route of administration and correlate with baseline enrichment of T and NK cell genes

Authors: Ayesa Syenina, Esther S Gan, Justin Z N Toh, Ruklanthi de Alwis, Lowell Z Lin, Christine Y L Tham, Jia Xin Yee, Yan Shan Leong, Huizhen Sam, Charlene Cheong, Yii Ean Teh, Ian L E Wee, Dorothy H L Ng, Kuan Rong Chan, Jean X Y Sim, Shirin Kalimuddin, Eugenia Z Ong, Jenny G Low, Eng Eong Ooi

Journal: PLoS Biol

PubMed ID: 35639676

Doi: 10.1371/journal.pbio.3001643

SEC is an antiangiogenic virulence factor that promotes endocarditis independent of superantigen activity

Authors: Kyle J Kinney, Sharon S Tang, Xiao-Jun Wu, Phuong M Tran, Nikhila S Bharadwaj, Katherine N Gibson-Corley, Ana N Forsythe, Katarina Kulhankova, Jenny E Gumperz, Wilmara Salgado-Pabón

Journal: Sci Adv

PubMed ID: 35544579

Doi: 10.1126/sciadv.abo1072

Products & Services: Gene Synthesis

High-throughput drug screening allowed identification of entry inhibitors specifically targeting different routes of SARS-CoV-2 Delta and Omicron/BA1

Authors: Maria Kuzikov, Jannis Woens, Andrea Zaliani, Julia Hambach, Thomas Eden, Boris Fehse, Bernhard Ellinger, Kristoffer Riecken

Journal: Biomed Pharmacother

PubMed ID: 35643072

Doi: 10.1016/j.biopha.2022.113104

Products & Services: Plasmid DNA Preparation

Characterization and clustering of kinase isoform expression in metastatic melanoma

Authors: David O Holland, Valer Gotea, Kevin Fedkenheuer, Sushil K Jaiswal, Catherine Baugher, Hua Tan, Michael Fedkenheuer, Laura Elnitski

Journal: PLoS Comput Biol

PubMed ID: 35560144

Doi: 10.1371/journal.pcbi.1010065

Products & Services: Gene Synthesis

Two Liberibacter Proteins Combine to Suppress Critical Innate Immune Defenses in Citrus

Authors: Supratim Basu, Loan Huynh, Shujian Zhang, Roel Rabara, Hau Nguyen, Jeanette Velásquez Guzmán, Guixia Hao, Godfrey Miles, Qingchun Shi, Ed Stover, Goutam Gupta

Journal: Front Plant Sci

PubMed ID: 35586217

Doi: 10.3389/fpls.2022.869178

Products & Services: PCR Cloning and Subcloning

Scalable biological signal recording in mammalian cells using Cas12a base editors

Authors: Hannah R Kempton, Kasey S Love, Lucie Y Guo, Lei S Qi

Journal: Nat Chem Biol

PubMed ID: 35637351

Doi: 10.1038/s41589-022-01034-2

Products & Services: ELISA Kits

Convergent Alterations of a Protein Hub Produce Divergent Effects within a Binding Site

Authors: Ali Imran, Brandon S Moyer, Dan Kalina, Thomas M Duncan, Kelsey J Moody, Aaron J Wolfe, Michael S Cosgrove, Liviu Movileanu

Journal: ACS Chem Biol

PubMed ID: 35613319

Doi: 10.1021/acschembio.2c00273

Products & Services: Protein and Antibody Isolation

The structural basis of Cdc7-Dbf4 kinase dependent targeting and phosphorylation of the MCM2-7 double hexamer

Authors: Almutasem Saleh, Yasunori Noguchi, Ricardo Aramayo, Marina E Ivanova, Kathryn M Stevens, Alex Montoya, S Sunidhi, Nicolas Lopez Carranza, Marcin J Skwark, Christian Speck

Journal: Nat Commun

PubMed ID: 35614055

Doi: 10.1038/s41467-022-30576-1

Products & Services: Mutant Libraries

Correlation Analysis of Anti-SARS-CoV-2 RBD IgG and Neutralizing Antibody against SARS-CoV-2 Omicron Variants after Vaccination

Authors: Nuchjira Takheaw, Chalerm Liwsrisakun, Warawut Chaiwong, Witida Laopajon, Supansa Pata, Juthamas Inchai, Pilaiporn Duangjit, Chaicharn Pothirat, Chaiwat Bumroongkit, Athavudh Deesomchok, Theerakorn Theerakittikul, Atikun Limsukon, Pattraporn Tajarernmuang, Nutchanok Niyatiwatchanchai, Konlawij Trongtrakul, Watchara Kasinrerk

Journal: Diagnostics (Basel)

PubMed ID: 35741126

Doi: 10.3390/diagnostics12061315

The phosphatase PTEN links platelets with immune regulatory functions of mouse T follicular helper cells

Authors: Xue Chen, Yanyan Xu, Qidi Chen, Heng Zhang, Yu Zeng, Yan Geng, Lei Shen, Fubin Li, Lei Chen, Guo-Qiang Chen, Chuanxin Huang, Junling Liu

Journal: Nat Commun

PubMed ID: 35589797

Doi: 10.1038/s41467-022-30444-y

Products & Services: Catalog Antibodies