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Neutralizing antibody and T cell responses against SARS-CoV-2 variants of concern following ChAdOx-1 or BNT162b2 boosting in the elderly previously immunized with CoronaVac vaccine

Authors: Chalerm Liwsrisakun, Supansa Pata, Witida Laopajon, Nuchjira Takheaw, Warawut Chaiwong, Juthamas Inchai, Chaicharn Pothirat, Chaiwat Bumroongkit, Athavudh Deesomchok, Theerakorn Theerakittikul, Atikun Limsukon, Pattraporn Tajarernmuang, Nutchanok Niyatiwatchanchai, Konlawij Trongtrakul, Kantinan Chuensirikulchai, Watchara Kasinrerk

Journal: Immun Ageing

PubMed ID: 35610643

Doi: 10.1186/s12979-022-00279-8

Products & Services: Protein and Antibody Isolation

Evaluating blood-brain barrier disruption and infarction volume concurrently in rats subjected to ischemic stroke using an optical imaging system

Authors: Yao He, Yingqian Zhang, Wanxin Li, Qinxi Li, Bangcheng Zhao, Xun Tang, Daojun Chen, Ting Zhang, Tao Zhang, Zhihui Zhong

Journal: J Neurosci Methods

PubMed ID: 35613659

Doi: 10.1016/j.jneumeth.2022.109630

Products & Services: Protein and Antibody Isolation

Functionalization of a symmetric protein scaffold: Redundant folding nuclei and alternative oligomeric folding pathways

Authors: Connie A Tenorio, Joseph B Parker, Michael Blaber

Journal: Protein Sci

PubMed ID: 35481645

Doi: 10.1002/pro.4301

Products & Services: Custom Vector Construction

The highly conserved stem-loop II motif is important for the lifecycle of astroviruses but dispensable for SARS-CoV-2

Authors: Andrew B Janowski, Hongbing Jiang, Chika Fujii, Macee C Owen, Traci L Bricker, Tamarand L Darling, Houda H Harastani, Kuljeet Seehra, Stephen Tahan, Ana Jung, Binita Febles, Joshua A Blatter, Scott A Handley, Bijal A Parikh, Valeria Lulla, Adrianus Cm Boon, David Wang

Journal: biorxiv

PubMed ID: 35547847

Doi: 10.1101/2022.04.30.486882

Products & Services: Plasmid DNA Preparation

FastCAT Accelerates Absolute Quantification of Proteins Using Multiple Short Nonpurified Chimeric Standards

Authors: Ignacy Rzagalinski, Aliona Bogdanova, Bharath Kumar Raghuraman, Eric R Geertsma, Lena Hersemann, Tjalf Ziemssen, Andrej Shevchenko

Journal: J Proteome Res

PubMed ID: 35561006

Doi: 10.1021/acs.jproteome.2c00014

Products & Services: Molecular Biology Tools

Characterization and clustering of kinase isoform expression in metastatic melanoma

Authors: David O Holland, Valer Gotea, Kevin Fedkenheuer, Sushil K Jaiswal, Catherine Baugher, Hua Tan, Michael Fedkenheuer, Laura Elnitski

Journal: PLoS Comput Biol

PubMed ID: 35560144

Doi: 10.1371/journal.pcbi.1010065

Products & Services: Gene Synthesis

Salt-inducible kinase 3 protects tumor cells from cytotoxic T-cell attack by promoting TNF-induced NF-κB activation

Authors: Antonio Sorrentino, Ayse Nur Menevse, Tillmann Michels, Valentina Volpin, Franziska Christine Durst, Julian Sax, Maria Xydia, Abir Hussein, Slava Stamova, Steffen Spoerl, Nicole Heuschneider, Jasmin Muehlbauer, Katharina Marlene Jeltsch, Anchana Rathinasamy, Melanie Werner-Klein, Marco Breinig, Damian Mikietyn, Christian Kohler, Isabel Poschke, Sabrina Purr, Olivia Reidell, Catarina Martins Freire, Rienk Offringa, Claudia Gebhard, Rainer Spang, Michael Rehli, Michael Boutros, Christian Schmidl, Nisit Khandelwal, Philipp Beckhove

Journal: J Immunother Cancer

PubMed ID: 35606086

Doi: 10.1136/jitc-2021-004258

Products & Services: Plasmid DNA Preparation

SARS-CoV-2-mRNA Booster Vaccination Reverses Non-Responsiveness and Early Antibody Waning in Immunocompromised Patients - A Phase Four Study Comparing Immune Responses in Patients With Solid Cancers, Multiple Myeloma and Inflammatory Bowel Disease

Authors: Angelika Wagner, Erika Garner-Spitzer, Anna-Margarita Schötta, Maria Orola, Andrea Wessely, Ines Zwazl, Anna Ohradanova-Repic, Lukas Weseslindtner, Gabor Tajti, Laura Gebetsberger, Bernhard Kratzer, Elena Tomosel, Maximilian Kutschera, Selma Tobudic, Winfried F Pickl, Michael Kundi, Hannes Stockinger, Gottfried Novacek, Walter Reinisch, Christoph Zielinski, Ursula Wiedermann

Journal: Front Immunol

PubMed ID: 35634285

Doi: 10.3389/fimmu.2022.889138

Disordered Regions Flanking the Binding Interface Modulate Affinity between CBP and NCOA

Authors: Elin Karlsson, Jan Schnatwinkel, Cristina Paissoni, Eva Andersson, Christian Herrmann, Carlo Camilloni, Per Jemth

Journal: J Mol Biol

PubMed ID: 35605677

Doi: 10.1016/j.jmb.2022.167643

Products & Services: Plasmid DNA Preparation

Maternal Exercise Before and During Pregnancy Facilitates Embryonic Myogenesis by Enhancing Thyroid Hormone Signaling

Authors: Yao Gao, Liang Zhao, Jun Seok Son, Xiangdong Liu, Yanting Chen, Jeanene Marie Deavila, Mei-Jun Zhu, Gordon K Murdoch, Min Du

Journal: Thyroid

PubMed ID: 35286177

Doi: 10.1089/thy.2021.0639

Products & Services: Gene Synthesis