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An auristatin-based peptide-drug conjugate targeting Kita-Kyushu lung cancer antigen 1 for precision chemoradiotherapy in gastric cancer

Authors: Xiaotong Chen , Fangcen Liu , Xiaoxiao Yu , Lin Li , Jiayao Yan , Xinjie Chen , Qin Liu , Baorui Liu

Journal: Eur J Med Chem

PubMed ID: 35932567

Doi: 10.1016/j.ejmech.2022.114617

Products & Services: Recombinant Antibody Expression

Independently evolved viral effectors convergently suppress DELLA protein SLR1-mediated broad-spectrum antiviral immunity in rice

Authors: Lulu Li , Hehong Zhang , Zihang Yang , Chen Wang , Shanshan Li , Chen Cao , Tongsong Yao , Zhongyan Wei , Yanjun Li , Jianping Chen , Zongtao Sun

Journal: Nat Commun

PubMed ID: 36376330

Doi: doi.org/10.1038/s41467-022-34649-z

Products & Services: Catalog Antibodies

Optimized prime editing in monocot plants using PlantPegDesigner and engineered plant prime editors (ePPEs)

Authors: Shuai Jin , Qiupeng Lin , Qiang Gao , Caixia Gao

Journal: Nat Protoc

PubMed ID: 36434096

Doi: doi.org/10.1038/s41596-022-00773-9

Products & Services: Catalog Antibodies

A gold nanoparticles-based lateral flow assay utilizing baculovirus expressed recombinant nucleocapsid and receptor binding domain proteins for serodetection of IgG and IgM against SARS-CoV-2

Authors: Reda Salem, Amany M Elshamy, Noha Kamel, Soha Younes, Ohoud M Marie, Fatma R Waly, Alaa A El-Kholy, Wael Elmenofy

Journal: Biotechnol Lett

PubMed ID: 36319880

Doi: 10.1007/s10529-022-03316-0

Products & Services: Mammalian Expression

The two Gtsf paralogs in silkworms orthogonally activate their partner PIWI proteins for target cleavage

Authors: Natsuko Izumi, Keisuke Shoji, Takashi Kiuchi, Susumu Katsuma, Yukihide Tomari

Journal: RNA

PubMed ID: 36319089

Doi: 10.1261/rna.079380.122

Products & Services: Gene Fragments

Antagonist of sphingosine 1-phosphate receptor 3 reduces cold injury of rat donor hearts for transplantation

Authors: Eisho Kanemitsu, Xiangdong Zhao, Keiko Iwaisako, Asuka Inoue, Akihide Takeuchi, Shintaro Yagi, Hidetoshi Masumoto, Hiroaki Ohara, Motoyasu Hosokawa, Tomonari Awaya, Junken Aoki, Etsuro Hatano, Shinji Uemoto, Masatoshi Hagiwara

Journal: Transl Res

PubMed ID: 36347491

Doi: 10.1016/j.trsl.2022.11.003

Products & Services: Codon Optimization

IgA quantification as a good predictor of the neutralizing antibodies levels after vaccination against SARS-CoV-2

Authors: Lorena O Fernandes-Siqueira, Bruna G Sousa, Carlos E Cleto, Luciana S Wermelinger, Beatriz L L Caetano, Agatha R Pacheco, Simone M Costa, Fabio C L Almeida, Gustavo C Ferreira, Didier Salmon, Ada M B Alves, Andrea T Da Poian

Journal: J Clin Virol Plus

PubMed ID: 36349309

Doi: 10.1016/j.jcvp.2022.100121

Neutralization Epitopes in Trimer and Pentamer Complexes Recognized by Potent Cytomegalovirus-Neutralizing Human Monoclonal Antibodies

Authors: Yuanbao Ai, Changwen Wu, Ming Zhang, Dabbu Kumar Jaijyan, Tong Liu, Lipeng Zan, Nan Li, Wei Yu, Yueming Wang, Xiaohui Yuan, Chengming Li, Weihong Zheng, Hua Zhu, Hua-Xin Liao

Journal: Microbiol Spectr

PubMed ID: 36342276

Doi: 10.1128/spectrum.01393-22

Products & Services: Protein and Antibody Isolation

Seroprevalence of AAV neutralizing antibodies in males with Duchenne muscular dystrophy

Authors: Sumit Verma, Stella N Nwosu, Raj Razdan, Saila R Upadhyayula, Han C Phan, Abubakarr A Koroma, Isai Leguizamo, Natalie S Correa, Michael Kuipa, David Lee, Thomas H Vanderford, Matthew R Gardner

Journal: Hum Gene Ther

PubMed ID: 36324212

Doi: 10.1089/hum.2022.081

Products & Services: Plasmid DNA Preparation

Monoallelic de novo AJAP1 loss-of-function variants disrupt trans-synaptic control of neurotransmitter release

Authors: Simon Fr h; Sami Boudkkazi; Peter Koppensteiner; Vita Sereikaite; Li-Yuan Chen; Diego Fernandez-Fernandez; Pascal D. Rem; Daniel Ulrich; Jochen Schwenk; Ziyang Chen; Elodie Le Monnier; Thorsten Fritzius; Sabrina M. Innocenti; Val rie Besseyrias; Luca Trov ; Michal Stawarski; Emanuela Argilli; Elliott H. Sherr; Bregje van Bon; Erik-Jan Kamsteeg; Maria Iascone; Alba Pilotta; Maria R. Cutr ; Mahshid S. Azamian; Andr s Hern ndez-Garc a; Seema R. Lalani; Jill A. Rosenfeld; Xiaonan Zhao; Tiphanie P. Vogel; Herda Ona; Daryl A. Scott; Peter Scheiffele; Kristian Str mgaard; Mehdi Tafti; Martin Gassmann; Bernd Fakler; Ryuichi Shigemoto; Bernhard Bettler

Journal: SCIENCE ADVANCES

PubMed ID: 38985877

Doi: 10.1126/sciadv.adk5462

Products & Services: Gene Fragments