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Computer-Aided Design of Lasso-like Self-Assembling Anticancer Peptides with Multiple Functions for Targeted Self-Delivery and Cancer Treatments

Authors: Pengfei Pei , Long Chen , Ruru Fan , Xi-Rui Zhou , Shan Feng , Hangrui Liu , Quanqiang Guo , Huiwei Yin , Qiang Zhang , Fude Sun , Liang Peng , Peng Wei , Chengzhi He , Renzhong Qiao , Zai Wang , Shi-Zhong Luo

Journal: ACS Nano

PubMed ID: 36099446

Doi: 10.1021/acsnano.2c01014

Products & Services: Peptide Synthesis

A bHLH transcription factor, SlbHLH96, promotes drought tolerance in tomato

Authors: Yunfei Liang , Fang Ma , Boyu Li , Cong Guo , Tixu Hu , Mingke Zhang , Yan Liang , Jianhua Zhu , Xiangqiang Zhan

Journal: Hortic Res

PubMed ID: 36467272

Doi: 10.1093/hr/uhac198

Products & Services: Protein and Antibody Isolation

GPBAR1 preserves neurite and synapse of dopaminergic neurons via RAD21-OPCML signaling: Role in preventing Parkinson's disease in mouse model and human patients

Authors: Yajie Zhang, Xin Sun, Youjiao Zhang, Zhengwei Kang, Lei Cai, Jianhua Ding, Ming Lu, Gang Hu

Journal: Pharmacol Res

PubMed ID: 36152741

Doi: 10.1016/j.phrs.2022.106459

Products & Services: Custom DNA/RNA Oligos

Squid Suckerin-Spider Silk Fusion Protein Hydrogel for Delivery of Mesenchymal Stem Cell Secretome to Chronic Wounds

Authors: Kenrick Koh, Jun Kit Wang, James Xiao Yuan Chen, Shu Hui Hiew, Hong Sheng Cheng, Bartosz Gabryelczyk, Marcus Ivan Gerard Vos, Yun Sheng Yip, Liyan Chen, Radoslaw M Sobota, Damian Kang Keat Chua, Nguan Soon Tan, Chor Yong Tay, Ali Miserez

Journal: Adv Healthc Mater

PubMed ID: 36177679

Doi: 10.1002/adhm.202201900

Products & Services: Protein and Antibody Isolation

Chondrogenic primed extracellular vesicles activate miR-455/SOX11/FOXO axis for cartilage regeneration and osteoarthritis treatment

Authors: Ye Sun, Jie Zhao, Qiang Wu, Yuxin Zhang, Yongqing You, Wenbo Jiang, Kerong Dai

Journal: NPJ Regen Med

PubMed ID: 36114225

Doi: 10.1038/s41536-022-00250-7

Products & Services: Gene Synthesis

Inhibition of Karyopherin β1-Mediated Nuclear Import Disrupts Oncogenic Lineage-Defining Transcription Factor Activity in Small Cell Lung Cancer

Authors: Demetra P Kelenis, Kathia E Rodarte, Rahul K Kollipara, Karine Pozo, Shreoshi Pal Choudhuri, Kyle B Spainhower, Sarah J Wait, Victor Stastny, Trudy G Oliver, Jane E Johnson

Journal: Cancer Res

PubMed ID: 35748745

Doi: 10.1158/0008-5472.CAN-21-3713

Products & Services: Gene Fragments

Proton-driven alternating access in a spinster lipid transporter

Authors: Reza Dastvan, Ali Rasouli, Sepehr Dehghani-Ghahnaviyeh, Samantha Gies, Emad Tajkhorshid

Journal: Nat Commun

PubMed ID: 36055994

Doi: 10.1038/s41467-022-32759-2

Products & Services: Custom Vector Construction

Anti-SARS-CoV-2 immunoadhesin remains effective against Omicron and other emerging variants of concern

Authors: Hadas Cohen-Dvashi, Jonathan Weinstein, Michael Katz, Maayan Eilon-Ashkenazy, Yuval Mor, Amir Shimon, Hagit Achdout, Hadas Tamir, Tomer Israely, Romano Strobelt, Maya Shemesh, Liat Stoler-Barak, Ziv Shulman, Nir Paran, Sarel Jacob Fleishman, Ron Diskin

Journal: iScience

PubMed ID: 36188189

Doi: 10.1016/j.isci.2022.105193

Products & Services: Mammalian Expression

DNA hypermethylation of promoter and reduction of hepatic Kiss1r in female rats with type 2 diabetes

Authors: Kamil Ziarniak, Tony Yang, Cayla Boycott, Megan Beetch, Maciej Sassek, Emilia Grzeda, Yuexi Ma, Joanna H Sliwowska, Barbara Stefanska

Journal: Epigenetics

PubMed ID: 36094166

Doi: 10.1080/15592294.2022.2119120

Products & Services: Gene Synthesis

A plant virus hijacks phosphatidylinositol-3,5-bisphosphate to escape autophagic degradation in its insect vector

Authors: Haitao Wang, Jianhua Zhang, Haoqiu Liu, Man Wang, Yan Dong, Yijun Zhou, Sek-Man Wong, Kai Xu, Qiufang Xu

Journal: Autophagy

PubMed ID: 36093594

Doi: 10.1080/15548627.2022.2116676

Products & Services: Protein Electrophoresis and Western