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GPBAR1 preserves neurite and synapse of dopaminergic neurons via RAD21-OPCML signaling: Role in preventing Parkinson's disease in mouse model and human patients

Authors: Yajie Zhang, Xin Sun, Youjiao Zhang, Zhengwei Kang, Lei Cai, Jianhua Ding, Ming Lu, Gang Hu

Journal: Pharmacol Res

PubMed ID: 36152741

Doi: 10.1016/j.phrs.2022.106459

Products & Services: Custom DNA/RNA Oligos

Molecular study on recombinant cold-adapted, detergent- and alkali stable esterase (EstRag) from Lysinibacillus sp.: a member of family VI.

Authors: Amira A Matrawy, Ahmed I Khalil, Amira M Embaby

Journal: World J Microbiol Biotechnol .

PubMed ID: 36070019

Doi: 10.1007/s11274-022-03402-5

Products & Services: Gene Synthesis

Arabidopsis Ubiquitin-Conjugating Enzymes UBC4, UBC5, and UBC6 Have Major Functions in Sugar Metabolism and Leaf Senescence

Authors: Sheng Wang , Ling Cao , Ian R Willick , Hong Wang , Karen K Tanino

Journal: Int J Mol Sci

PubMed ID: 36232444

Doi: ijms231911143

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HOXB13 facilitates hepatocellular carcinoma progression by activating AKT/mTOR signaling pathway

Authors: Miao Li, Tingting Tan, Yu Geng, Yue Tao, Jie Pan, Jun Zhang, Qin Xu, Han Shen, Lingyun Zuo, Yuxin Chen

Journal: Ann Hepatol

PubMed ID: 36179794

Doi: 10.1016/j.aohep.2022.100759

Products & Services: CRISPR Plasmids

An investigation across 45 languages and 12 language families reveals a universal language network

Authors: Saima Malik-Moraleda, Dima Ayyash, Jeanne Gallée, Josef Affourtit, Malte Hoffmann, Zachary Mineroff, Olessia Jouravlev, Evelina Fedorenko

Journal: Nat Neurosci

PubMed ID: 35856094

Doi: 10.1038/s41593-022-01114-5

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GAPDH mediates plant reovirus-induced incomplete autophagy for persistent viral infection in leafhopper vector

Authors: Qian Chen, Yuele Zhang, Hengsong Yang, Xin Wang, Jiping Ren, Dongsheng Jia, Hongyan Chen, Taiyun Wei

Journal: Autophagy

PubMed ID: 36036160

Doi: 10.1080/15548627.2022.2115830

Products & Services: Polyclonal Antibody Services

Conformational buffering underlies functional selection in intrinsically disordered protein regions

Authors: Nicolás S González-Foutel, Juliana Glavina, Wade M Borcherds, Matías Safranchik, Susana Barrera-Vilarmau, Amin Sagar, Alejandro Estaña, Amelie Barozet, Nicolás A Garrone, Gregorio Fernandez-Ballester, Clara Blanes-Mira, Ignacio E Sánchez, Gonzalo de Prat-Gay, Juan Cortés, Pau Bernadó, Rohit V Pappu, Alex S Holehouse, Gary W Daughdrill, Lucía B Chemes

Journal: Nat Struct Mol Biol

PubMed ID: 35948766

Doi: 10.1038/s41594-022-00811-w

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Identification of linear epitopes and their major role in the immunoglobulin E-binding capacity of tropomyosin from

Authors: Nai-Ru Ji, Xin-Yu Han, Chen-Chen Yu, Xin-Rong He, Shi-Tao Rao, Fei Huan, Hong Liu, Gui-Xia Chen, Min-Jie Cao, Guang-Ming Liu

Journal: Food Funct

PubMed ID: 35943407

Doi: 10.1039/d2fo01713j

Products & Services: Peptide Synthesis

AL101, a gamma-secretase inhibitor, has potent antitumor activity against adenoid cystic carcinoma with activated NOTCH signaling

Authors: Renata Ferrarotto, Vasudha Mishra, Elad Herz, Adar Yaacov, Oz Solomon, Rami Rauch, Adi Mondshine, Maria Motin, Tal Leibovich-Rivkin, Matti Davis, Joel Kaye, Christopher R Weber, Le Shen, Alexander T Pearson, Ari J Rosenberg, Xiangying Chen, Alka Singh, Jon C Aster, Nishant Agrawal, Evgeny Izumchenko

Journal: Cell Death Dis

PubMed ID: 35931701

Doi: 10.1038/s41419-022-05133-9

Products & Services: Mammalian Expression

Oral glucagon-like peptide 1 analogue ameliorates glucose intolerance in db/db mice

Authors: Hanlin Zhang, Meng Dong, Shouli Yuan, Wanzhu Jin

Journal: Biotechnol Lett

PubMed ID: 36006576

Doi: 10.1007/s10529-022-03288-1

Products & Services: Peptide Synthesis