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Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease

Authors: Raaj S Mehta, Jared R Mayers, Yancong Zhang, Amrisha Bhosle, Nathaniel R Glasser, Long H Nguyen, Wenjie Ma, Sena Bae, Tobyn Branck, Kijun Song, Luke Sebastian, Julian Avila Pacheco, Hyuk-Soo Seo, Clary Clish, Sirano Dhe-Paganon, Ashwin N Ananthakrishnan, Eric A Franzosa, Emily P Balskus, Andrew T Chan, Curtis Huttenhower

Journal: Nat Med

PubMed ID: 36823301

Doi: 10.1038/s41591-023-02217-7

Products & Services: Protein and Antibody Isolation

Exocytic machineries differentially control mediator release from allergen-triggered RBL-2H3 cells

Authors: Pratikshya Adhikari, Tolulope E Ayo, John C Vines, Shuzo Sugita, Hao Xu

Journal: Inflamm Res

PubMed ID: 36725743

Doi: 10.1007/s00011-023-01698-z

Products & Services: Protein and Antibody Isolation

Transplantation of A2 type astrocytes promotes neural repair and remyelination after spinal cord injury

Authors: Jie Chang, Zhanyang Qian, Binyu Wang, Jiang Cao, Sheng Zhang, Fan Jiang, Renyi Kong, Xiao Yu, Xiaojian Cao, Lei Yang, Hongtao Chen

Journal: Cell Commun Signal

PubMed ID: 36797790

Doi: 10.1186/s12964-022-01036-6

Products & Services: Protein and Antibody Isolation

Generation of TGFβR2(-1) neoantigen-specific HLA-DR4-restricted T cell receptors for cancer therapy

Authors: Natalia Plewa, Lucia Poncette, Thomas Blankenstein

Journal: J Immunother Cancer

PubMed ID: 36822673

Doi: 10.1136/jitc-2022-006001

Products & Services: Peptide Synthesis

Function of the bacteriophage P2 baseplate central spike Apex domain in the infection process

Authors: John-Mark Miller, Ekaterina S Knyazhanskaya, Sergii A Buth, Nikolai S Prokhorov, Petr G Leiman

Journal: biorxiv

PubMed ID: 36865152

Doi: 10.1101/2023.02.25.529910

Products & Services: Protein and Antibody Isolation

A novel binary pesticidal protein from Chryseobacterium arthrosphaerae controls western corn rootworm by a different mode of action to existing commercial pesticidal proteins

Authors: Rania Jabeur, Virginie Guyon, Szabolcs Toth, Adriano E Pereira, Man P Huynh, Zakia Selmani, Erin Boland, Mickael Bosio, Laurent Beuf, Pete Clark, David Vallenet, Wafa Achouak, Carine Audiffrin, François Torney, Wyatt Paul, Thierry Heulin, Bruce E Hibbard, Stefan Toepfer, Christophe Sallaud

Journal: PLoS ONE

PubMed ID: 36800363

Doi: 10.1371/journal.pone.0267220

Products & Services: Protein and Antibody Isolation

pH-Sensitive and Biodegradable Mn3(PO4)2·3H2O Nanoparticles as an Adjuvant of Protein-Based Bivalent COVID-19 Vaccine to Induce Potent and Broad-Spectrum Immunity

Authors: Shi-Hao Zhou,‡Ru-Yan Zhang,Zi-Wei You, Yong-Ke Zou, Yu Wen, Jian Wang, Dong Ding, Miao-Miao Bian, Zhi-Ming Zhang, Hong Yuan, Guang-Fu Yang, and Jun Guo

Journal: ACS Applied Materials & Interfaces

Doi: 10.1021/acsami.2c19736

Products & Services: Recombinant Proteins

Revealing the role of tunable amino acid residues in elastin-like polypeptides (ELPs)-mediated biomimetic silicification

Authors: Yue Qiu , Yuanqing Lin , Bo Zeng , Peiliang Qin , Zhiwei Yi , Guangya Zhang

Journal: Int J Biol Macromol

PubMed ID: 36539170

Doi: 10.1016/j.ijbiomac.2022.12.152

Products & Services: Gene Synthesis

Multi-omic screening of invasive GBM cells in engineered biomaterials and patient biopsies reveals targetable transsulfuration pathway alterations

Authors: Joseph H Garcia, Erin A Akins, Saket Jain, Kayla J Wolf, Jason Zhang, Nikita Choudhary, Meeki Lad, Poojan Shukla, Sabraj Gill, Will Carson, Luis Carette, Allison Zheng, Sanjay Kumar, Manish K Aghi

Journal: biorxiv

PubMed ID: 36865128

Doi: 10.1101/2023.02.23.529575

Products & Services: Peptide Synthesis

SARS-CoV-2 Main Protease Targets Host Selenoproteins and Glutathione Biosynthesis for Knockdown via Proteolysis, Potentially Disrupting the Thioredoxin and Glutaredoxin Redox Cycles

Authors: Ignacio A Gallardo, Daniel A Todd, Stella T Lima, Jonathan R Chekan, Norman H Chiu, Ethan Will Taylor

Journal: Antioxidants (Basel)

PubMed ID: 36978807

Doi: 10.3390/antiox12030559

Products & Services: Protein and Antibody Isolation