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Developing deprotectase biocatalysts for synthesis

Authors: Lisa Kennedy, Mariyah Sajjad, Michael A Herrera, Peter Szieber, Natasza Rybacka, Yinan Zhao, Craig Steven, Zainab Alghamdi, Ivan Zlatkov, Julie Hagen, Chloe Lauder, Natalie Rudolfova, Magdalena Abramiuk, Karolina Bolimowska, Daniel Joynt, Angelica Lucero, Gustavo Perez Ortiz, Annamaria Lilienkampf, Alison N Hulme, Dominic J Campopiano

Journal: Faraday Discuss

PubMed ID: 38856717

Doi: 10.1039/d4fd00016a

Products & Services: Gene Synthesis

Nonclinical immunogenicity risk assessment for knobs-into-holes bispecific IgG antibodies

Authors: Wen-Ting K Tsai, Yinyin Li, Zhaojun Yin, Peter Tran, Qui Phung, Zhenru Zhou, Kun Peng, Dan Qin, Sien Tam, Christoph Spiess, Jochen Brumm, Manda Wong, Zhengmao Ye, Patrick Wu, Sivan Cohen, Paul J Carter

Journal: MAbs

PubMed ID: 38845069

Doi: 10.1080/19420862.2024.2362789

Products & Services: Gene Synthesis

Aerobic exercise-induced HIF-1α upregulation in heart failure: exploring potential impacts on MCT1 and MPC1 regulation

Authors: Longfei Xu, Miaomiao Yang, Aili Wei, Zilin Wei, Yingkai Qin, Kun Wang, Bin Li, Kang Chen, Chen Liu, Chao Li, Tianhui Wang

Journal: Mol Med

PubMed ID: 38867145

Doi: 10.1186/s10020-024-00854-3

Products & Services: Protein and Antibody Isolation

MCTP1 increases the malignancy of androgen-deprived prostate cancer cells by inducing neuroendocrine differentiation and EMT

Authors: Yen-Nien Liu, Wei-Yu Chen, Hsiu-Lien Yeh, Wei-Hao Chen, Kuo-Ching Jiang, Han-Ru Li, Phan Vu Thuy Dung, Zi-Qing Chen, Wei-Jiunn Lee, Michael Hsiao, Jiaoti Huang, Yu-Ching Wen

Journal: Sci Signal

PubMed ID: 38861615

Doi: 10.1126/scisignal.adc9142

Products & Services: Protein and Antibody Isolation

Down-regulation of SLC14A1 in prostate cancer activates CDK1/CCNB1 and mTOR pathways and promotes tumor progression

Authors: Jianbin Ma, Kaihua Xue, Yifan Jiang, Xinyang Wang, Dalin He, Peng Guo

Journal: Sci Rep

PubMed ID: 38942821

Doi: 10.1038/s41598-024-66020-1

Products & Services: Molecular Biology Reagents

Neutralizing antibodies reveal cryptic vulnerabilities and interdomain crosstalk in the porcine deltacoronavirus spike protein

Authors: Wenjuan Du, Oliver Debski-Antoniak, Dubravka Drabek, Rien van Haperen, Melissa van Dortmondt, Joline van der Lee, Ieva Drulyte, Frank J M van Kuppeveld, Frank Grosveld, Daniel L Hurdiss, Berend-Jan Bosch

Journal: Nat Commun

PubMed ID: 38909062

Doi: 10.1038/s41467-024-49693-0

Products & Services: DNA Sequencing

Anaplastic Lymphoma Kinase signaling stabilizes SLC3A2 expression via MARCH11 to promote neuroblastoma cell growth

Authors: Wei-Yun Lai, Tzu-Po Chuang, Marcus Borenäs, Dan E Lind, Bengt Hallberg, Ruth H Palmer

Journal: Cell Death Differ

PubMed ID: 38858548

Doi: 10.1038/s41418-024-01319-0

Products & Services: Molecular Biology Reagents

Puferfsh gasdermin Ea is a signifcant player in the defense against bacterial pathogens

Authors: Hang Xu, Kunpeng Qin, Kangwei Hao, Zihao Yuan & Li Sun

Journal: Marine Life Science & Technology

Doi: //doi.org/10.1007/s42995-024-00237-x

Products & Services: Protein and Antibody Isolation

Lipid-Polymer Nanoparticles Mediate Compartmentalized Delivery of Cas9 and sgRNA for Glioblastoma Vasculature and Immune Reprogramming

Authors: Huaqing Zhang, Wenxin Jiang, Tingting Song, Mingjie Song, Shengyu Liu, Jianping Zhou, Hao Cheng, Yang Ding

Journal: Adv Sci (Weinh)

PubMed ID: 38923275

Doi: 10.1002/advs.202309314

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

CD147-K148me2-Driven Tumor Cell-Macrophage Crosstalk Provokes NSCLC Immunosuppression via the CCL5/CCR5 Axis

Authors: Ke Wang, Xiaohong Chen, Peng Lin, Jiao Wu, Qiang Huang, Zhi-Nan Chen, Jiale Tian, Hao Wang, Ye Tian, Mingyan Shi, Meirui Qian, Bengang Hui, Yumeng Zhu, Ling Li, Rui Yao, Huijie Bian, Ping Zhu, Ruo Chen, Liang Chen

Journal: Adv Sci (Weinh)

PubMed ID: 38873823

Doi: 10.1002/advs.202400611

Products & Services: Recombinant Proteins