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Induction of lung mucosal immunity by a next-generation inhaled aerosol COVID-19 vaccine: an open-label, multi-arm phase 1 clinical trial

Authors: Mangalakumari Jeyanathan, Sam Afkhami, Michael R D'Agostino, Imran Satia, Dominik K Fritz, Kate Miyasaki, Jann C Ang, Anna Zganiacz, Karen J Howie, Marilyn Swinton, Emilio Aguirre, Michael B Zheng, Natallia Kazhdan, Anna Dvorkin-Gheva, Lawrence Mbuagbaw, Maria Fe C Medina, Nermin Diab, Danica L Brister, Gail M Gauvreau, Brian D Lichty, Matthew S Miller, Fiona Smaill, Zhou Xing

Journal: Nature Communications

PubMed ID: 40603330

Doi: 10.1038/s41467-025-60726-0

Products & Services: Codon Optimization

PPP2R1A mutations portend improved survival after cancer immunotherapy

Authors: Yibo Dai, Anne Knisely, Mitsutake Yano, Minghao Dang, Emily M Hinchcliff, Sanghoon Lee, Annalyn Welp, Manoj Chelvanambi, Matthew Lastrapes, Heng Liu, Zhe Yuan, Chen Wang, Hao Nie, Stephanie Jean, Luis J Montaner, Jiakai Hou, Ami Patel, Shrina Patel, Bryan Fellman, Ying Yuan, Baohua Sun, Renganayaki Krishna Pandurengan, Edwin Roger Parra Cuentas, Joseph Celestino, Yan Liu, Jinsong Liu, R Tyler Hillman, Shannon N Westin, Anil K Sood, Pamela T Soliman, Aaron Shafer, Larissa A Meyer, David M Gershenson, David Vining, Dhakshinamoorthy Ganeshan, Karen Lu, Jennifer A Wargo, Weiyi Peng, Rugang Zhang, Linghua Wang, Amir A Jazaeri

Journal: Nature

PubMed ID: 40604275

Doi: 10.1038/s41586-025-09203-8

Products & Services: Gene Synthesis

Analysis of the Rehmannia chingii geneome identifies RcCYP72H7 as an epoxidase in iridoid glycoside biosynthesis

Authors: Fengqing Wang, Zhennan Jiang, Junge Gao, Chunyan Miao, Ci Song, Yahe Yang, Ning Ding, Yajing Li, Hongzheng Sun, Caixia Xie, Bao Zhang, Pengyu Zhang, Li Gu, Qiuwen Hao, Zhongyi Zhang, Luqi Huang, Yuan Yuan

Journal: Nature Communications

PubMed ID: 40593652

Doi: 10.1038/s41467-025-60909-9

Products & Services: Protein Electrophoresis and Western

Human neutrophil α-defensin HNP1 interacts with bacterial OmpA to promote Acinetobacter baumannii biofilm formation

Authors: Chongbing Liao, Qihui Liu, Gan Luo, Yinyue Luo, Dan Yao, Qingxia Wang, Jue Zhang, Yang Wu, Jialin Jin, Dan Xu, Wuyuan Lu

Journal: Nature Communications

PubMed ID: 40595622

Doi: 10.1038/s41467-025-60935-7

Products & Services: Protein Electrophoresis and Western

HIV-1 vif mediates ubiquitination of the proximal protomer in the APOBEC3H dimer to induce degradation

Authors: Katarzyna A Skorupka, Kazuhiro Matsuoka, Bakar Hassan, Rodolfo Ghirlando, Vanivilasini Balachandran, Ting-Hua Chen, Kylie J Walters, Celia A Schiffer, Matthias Wolf, Yasumasa Iwatani, Hiroshi Matsuo

Journal: Nature Communications

PubMed ID: 40593686

Doi: 10.1038/s41467-025-60984-y

Products & Services: Gene Synthesis

The haplotype-resolved telomere-to-telomere genome and OMICS analyses reveal genetic responses to tapping in rubber tree

Authors: Chaochao Li, Yuan Yuan, Zhiyi Nie, Tingkai Wu, Zhiyuan Wang, Jiangxia Qiao, Zhi Deng, Xiaobo Wang, Dong Xu, Xu Wang, Shuo Cao, Bingqin Li, Zewei An, Wenguan Wu, Zhongxin Jin, Huasun Huang, Wei Hu, Yongfeng Zhou, Han Cheng

Journal: Nature Communications

PubMed ID: 40624070

Doi: 10.1038/s41467-025-61527-1

Products & Services: Protein and Antibody Isolation

Structural basis for engagement of Western Equine Encephalitis Virus with the PCDH10 receptor

Authors: Shengjian Liang, Yan Yang, Yixiao Liu, Zhili Xu, Jichao Hou, Donghan Li, Lixin Zhao, Chuyu Hu, Xiaoke Liu, Zihe Rao, Yanyi Wang, Zhiyong Lou

Journal: Nature Communications

PubMed ID: 40628733

Doi: 10.1038/s41467-025-61659-4

Products & Services: Protein and Antibody Isolation

The defensome of prokaryotes in aquifers

Authors: Pengwei Li, Zongzhi Wu, Tang Liu, Chunfang Deng, Quan Liu, Jinren Ni

Journal: Nature Communications

PubMed ID: 40659683

Doi: 10.1038/s41467-025-61467-w

Products & Services: PCR Cloning and Subcloning

Staphylococcus aureus LukMF' targets neutrophils to promote skin and soft tissue infection

Authors: Daiane Boff, Ravishankar Chandrasekaran, Gregory Putzel, Rachel M Kratofil, Xuhui Zheng, Ashley Castellaw, Kody Mansfield, Ikjot Sidhu, Avantika Dhabaria, Keenan A Lacey, Sandra Gonzalez, Filadelfia Tadjibaeva, Beatrix Ueberheide, Cynthia Loomis, Alejandro Pironti, Silva Holtfreter, Shruti Naik, Victor J Torres

Journal: SCIENCE ADVANCES

PubMed ID: 40614206

Doi: 10.1126/sciadv.adr5240

Products & Services: Endotoxin Detection & Removal System

Optimizing a human monoclonal antibody for better neutralization of SARS-CoV-2

Authors: Qian Wang, Yicheng Guo, Ryan G Casner, Jian Yu, Manoj S Nair, Jerren Ho, Eswar R Reddem, Ian A Mellis, Madeline Wu, Chih-Chen Tzang, Hsiang Hong, Yaoxing Huang, Lawrence Shapiro, Lihong Liu, David D Ho

Journal: Nature Communications

PubMed ID: 40615407

Doi: 10.1038/s41467-025-61472-z

Products & Services: Gene Synthesis