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Non-antibiotics disrupt colonization resistance against enteropathogens

Authors: Anne Grießhammer, Jacobo de la Cuesta-Zuluaga, Patrick Müller, Cordula Gekeler, Jan Homolak, Hsuan Chang, Katharina Schmitt, Chiara Planker, Verena Schmidtchen, Suchira Gallage, Erwin Bohn, Taylor H Nguyen, Jenny Hetzer, Mathias Heikenwälder, Kerwyn Casey Huang, Taiyeb Zahir, Lisa Maier

Journal: Nature

PubMed ID: 40670795

Doi: 10.1038/s41586-025-09217-2

Products & Services: Gene Synthesis

The mitotic chromosome periphery modulates chromosome mechanics

Authors: Tania Mendonca, Roman Urban, Kellie Lucken, George Coney, Neil M Kad, Manlio Tassieri, Amanda J Wright, Daniel G Booth

Journal: Nature Communications

PubMed ID: 40640170

Doi: 10.1038/s41467-025-61755-5

Products & Services: Gene Synthesis

Structure-guided engineering of snake toxins for selective modulation of adrenergic and muscarinic receptors

Authors: Yixuan Zhong, Huihui Tao, Yu Zhang, Binbin He, Haizhan Jiao, Dandan Wang, Maikun Teng, Hongli Hu, Qiong Guo, Yuyong Tao

Journal: Nature Communications

PubMed ID: 40659608

Doi: 10.1038/s41467-025-61695-0

Natural variation of an E3 ubiquitin ligase encoding gene Chalk9 regulates grain chalkiness in rice

Authors: Zhi Hu, Hongchun Liu, Min Guo, Xiang Han, Youguang Li, Rujia Chen, Yifan Guo, Yihao Yang, Shengyuan Sun, Yong Zhou, Minghong Gu, Changjie Yan

Journal: Nature Communications

PubMed ID: 40683885

Doi: 10.1038/s41467-025-61683-4

Products & Services: Polyclonal Antibody Services

Rice E3 ubiquitin ligase BLAST AND BTH-INDUCED 1 targets jasmonic acid signaling co-repressors to release Myelocytomatosis protein 2 for modulating immune responses against blast fungus

Authors: Yan Bi , Yuqing Yan , Hui Wang , Leeza Tariq , Dayong Li , Fengming Song

Journal: International Journal of Biological Macromolecules

PubMed ID: 40543771

Doi: doi.org/10.1016/j.ijbiomac.2025.145363

Products & Services: Catalog Peptides

LEDGF Binds H3R17me2a Promoting De Novo Nucleotide Biosynthesis in SETD2 Mutant Clear Cell Renal Cell Carcinoma

Authors: Yuwei Zhang, Yuhua Zhou, Yuezhou Zhang, Jing Lv, Yang Shen, Dong Zhang, Bo Liu, Wei Zhao, Junyi Ju, Qingyi Zhu, Ke Wang, Ninghan Feng

Journal: Advanced Science

Doi: doi.org/10.1002/advs.202416809

Products & Services: Peptide Synthesis

Activation of mechanosensitive ion channel Piezo1 linking metabolic reprogramming and pro-inflammatory responses in hepatocellular carcinoma

Authors: Juanfen Mo, YuXuan Zhang, Chenxi Cao, WeiLi Zheng, Li Zheng, Xiaoguang Wang, Shiyue Wang, Jiayuan Wu, Yi Bao

Journal: Cell Communication and Signaling

PubMed ID: 40514668

Doi: 10.1186/s12964-025-02289-7

Products & Services: Protein and Antibody Isolation

Topical delivery of a human single-domain antibody targeting IL-33 to inhibit mucosal inflammation

Authors: Keke Huang, Yuqing Wu, Yu Kong, Qingyuan Xu, Mingwei Lv, Yirou Zhang, Yiteng Lu, Quanxiao Li, Cheng Li, Wenping Song, Xiaoyi Zhu, Zhenlin Yang, Changchang Xin, Xujiao Zhou, Tianlei Ying, Yanling Wu, Jiaxu Hong

Journal: Cellular & molecular immunology

PubMed ID: 40500403

Doi: 10.1038/s41423-025-01305-7

Products & Services: Protein and Antibody Isolation

An all-silk-based functional system promotes tendon regeneration by regulating the cell fate of TSPCs in an inflammatory microenvironment

Authors: Qingyun Mo, Haotian Zheng, Chuanquan Liu, Yuzhi Sun, Zhicheng Cao, Renwang Sheng, Yanan Zhang, Mingyue Wang, Baian Kuang, Ludvig J Backman, Jiaxiang Li, Wei Zhang, Jialin Chen

Journal: Acta Biomaterialia

PubMed ID: 40409996

Doi: 10.1016/j.actbio.2025.05.040

Products & Services: Recombinant Proteins

AIDS patients suffer higher risk of advanced knee osteoarthritis progression due to lopinavir-induced Zmpste24 inhibition

Authors: Keyu Kong, Li Liu, Renfang Zhang, Yongyun Chang, Yueming Shao, Chen Zhao, Hua Qiao, Minghao Jin, Xuzhuo Chen, Wentao Shi, Xinru Wu, Wenxuan Fan, Yuehao Hu, Kewei Rong, Pu Zhang, Baixing Li, Jingwei Zhang, Peixiang Ma, Xiaoling Zhang, Huiwu Li, Zanjing Zhai

Journal: Bone Research

PubMed ID: 40461512

Doi: 10.1038/s41413-025-00431-2

Products & Services: Recombinant Proteins