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High-fidelity DNA polymerase for DNA-based digital Information Storage

Authors: Xutong Liu, Kai Wen, Enyang Yu, Qixuan Zhao, Haoran Fu, Jingxuan Zhu, Haobo Han, Quanshun Li

Journal: Small Methods

PubMed ID: 40665906

Doi: 10.1002/smtd.202500817

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Metabotropic glutamate receptor 4-mediated glutamatfergic signaling reshapes the tumor microenvironment by regulating dendritic cell maturation

Authors: Xiaoman Ju, Eva Maria Putz, Yaqi Liu, Dongchen Yuan, Guowei Sun, Stephane Koda, Zhuo Fu, Simin Shao, Chunrong Tong, Biping Deng, Jing Hu, Juming Yan

Journal: Nature Communications

PubMed ID: 40593670

Doi: 10.1038/s41467-025-60922-y.

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CRISPRi screen identifies FprB as a synergistic target for gallium therapy in Pseudomonas aeruginosa

Authors: Yu Zhang, Tingting Zhang, Xue Xiao, Yejun Wang, Adam Kawalek, Jinzhao Ou, Anmin Ren, Wenhao Sun, Vincent de Bakker, Yujie Liu, Yuelong Li, Liang Yang, Liang Ye, Ning Jia, Jan-Willem Veening, Xue Liu

Journal: Nature Communications

PubMed ID: 40595632

Doi: 10.1038/s41467-025-61208-z

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DRAM1 promotes the stability of lysosomal VAMP8 to enhance autolysosome formation and facilitates the extravasation

Authors: Rui Zhang, Xin Zhang, Hua Bai, Qiuyu Cheng, Xia Yao, Shi Li, Vincenzo Torraca, Chaojun Yan, Xueying Dong, Siyi Miao, Xueyuan Hu, Yeping Yu, Yueyan Wu, Hongfei Tan, Xin Chen, Shicheng Liu, Hao Lyu, Shuai Xiao, Dong Guo, Qi Zhang, Xing-Zhen Chen, Zhiyin Song, Cefan Zhou, Jingfeng Tang

Journal: Nature Communications

PubMed ID: 40595569

Doi: 10.1038/s41467-025-60887-y

Induction of lung mucosal immunity by a next-generation inhaled aerosol COVID-19 vaccine: an open-label, multi-arm phase 1 clinical trial

Authors: Mangalakumari Jeyanathan, Sam Afkhami, Michael R D'Agostino, Imran Satia, Dominik K Fritz, Kate Miyasaki, Jann C Ang, Anna Zganiacz, Karen J Howie, Marilyn Swinton, Emilio Aguirre, Michael B Zheng, Natallia Kazhdan, Anna Dvorkin-Gheva, Lawrence Mbuagbaw, Maria Fe C Medina, Nermin Diab, Danica L Brister, Gail M Gauvreau, Brian D Lichty, Matthew S Miller, Fiona Smaill, Zhou Xing

Journal: Nature Communications

PubMed ID: 40603330

Doi: 10.1038/s41467-025-60726-0

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PPP2R1A mutations portend improved survival after cancer immunotherapy

Authors: Yibo Dai, Anne Knisely, Mitsutake Yano, Minghao Dang, Emily M Hinchcliff, Sanghoon Lee, Annalyn Welp, Manoj Chelvanambi, Matthew Lastrapes, Heng Liu, Zhe Yuan, Chen Wang, Hao Nie, Stephanie Jean, Luis J Montaner, Jiakai Hou, Ami Patel, Shrina Patel, Bryan Fellman, Ying Yuan, Baohua Sun, Renganayaki Krishna Pandurengan, Edwin Roger Parra Cuentas, Joseph Celestino, Yan Liu, Jinsong Liu, R Tyler Hillman, Shannon N Westin, Anil K Sood, Pamela T Soliman, Aaron Shafer, Larissa A Meyer, David M Gershenson, David Vining, Dhakshinamoorthy Ganeshan, Karen Lu, Jennifer A Wargo, Weiyi Peng, Rugang Zhang, Linghua Wang, Amir A Jazaeri

Journal: Nature

PubMed ID: 40604275

Doi: 10.1038/s41586-025-09203-8

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Analysis of the Rehmannia chingii geneome identifies RcCYP72H7 as an epoxidase in iridoid glycoside biosynthesis

Authors: Fengqing Wang, Zhennan Jiang, Junge Gao, Chunyan Miao, Ci Song, Yahe Yang, Ning Ding, Yajing Li, Hongzheng Sun, Caixia Xie, Bao Zhang, Pengyu Zhang, Li Gu, Qiuwen Hao, Zhongyi Zhang, Luqi Huang, Yuan Yuan

Journal: Nature Communications

PubMed ID: 40593652

Doi: 10.1038/s41467-025-60909-9

Products & Services: Protein Electrophoresis and Western

Human neutrophil α-defensin HNP1 interacts with bacterial OmpA to promote Acinetobacter baumannii biofilm formation

Authors: Chongbing Liao, Qihui Liu, Gan Luo, Yinyue Luo, Dan Yao, Qingxia Wang, Jue Zhang, Yang Wu, Jialin Jin, Dan Xu, Wuyuan Lu

Journal: Nature Communications

PubMed ID: 40595622

Doi: 10.1038/s41467-025-60935-7

Products & Services: Protein Electrophoresis and Western

HIV-1 vif mediates ubiquitination of the proximal protomer in the APOBEC3H dimer to induce degradation

Authors: Katarzyna A Skorupka, Kazuhiro Matsuoka, Bakar Hassan, Rodolfo Ghirlando, Vanivilasini Balachandran, Ting-Hua Chen, Kylie J Walters, Celia A Schiffer, Matthias Wolf, Yasumasa Iwatani, Hiroshi Matsuo

Journal: Nature Communications

PubMed ID: 40593686

Doi: 10.1038/s41467-025-60984-y

Products & Services: Gene Synthesis

Staphylococcus aureus LukMF' targets neutrophils to promote skin and soft tissue infection

Authors: Daiane Boff, Ravishankar Chandrasekaran, Gregory Putzel, Rachel M Kratofil, Xuhui Zheng, Ashley Castellaw, Kody Mansfield, Ikjot Sidhu, Avantika Dhabaria, Keenan A Lacey, Sandra Gonzalez, Filadelfia Tadjibaeva, Beatrix Ueberheide, Cynthia Loomis, Alejandro Pironti, Silva Holtfreter, Shruti Naik, Victor J Torres

Journal: SCIENCE ADVANCES

PubMed ID: 40614206

Doi: 10.1126/sciadv.adr5240

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