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Epicardium-derived cells organize through tight junctions to replenish cardiac muscle in salamanders

Authors: Elif Eroglu, Christopher Y T Yen, Yat-Long Tsoi, Nevin Witman, Ahmed Elewa, Alberto Joven Araus, Heng Wang, Tamara Szattler, Chimezie H Umeano, Jesper Sohlmér, Alexander Goedel, András Simon, Kenneth R Chien

Journal: Nat Cell Biol

PubMed ID: 35550612

Doi: 10.1038/s41556-022-00902-2

Products & Services: Plasmid DNA Preparation

Structure and Mechanism of a Cold-Adapted Bacterial Lipase

Authors: Florian van der Ent, Bjarte A Lund, Linn Svalberg, Miha Purg, Ghislean Chukwu, Mikael Widersten, Geir V Isaksen, Bjørn O Brandsdal, Johan Åqvist

Journal: Biochemistry

PubMed ID: 35503728

Doi: 10.1021/acs.biochem.2c00087

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Fermentative Indole Production via Bacterial Tryptophan Synthase Alpha Subunit and Plant Indole-3-Glycerol Phosphate Lyase Enzymes

Authors: Lenny Ferrer, Melanie Mindt, Maria Suarez-Diez, Tatjana Jilg, Maja Zagorščak, Jin-Ho Lee, Kristina Gruden, Volker F Wendisch, Katarina Cankar

Journal: J Agric Food Chem

PubMed ID: 35500281

Doi: 10.1021/acs.jafc.2c01042

Products & Services: PCR Cloning and Subcloning

Quantitative proteomics of HFD-induced fatty liver uncovers novel transcription factors of lipid metabolism

Authors: Shang Zhi, Zhang Congcong, Gao Zhiling, Qian Yihan, Xin Yijing, Liu Guanjie, Wang Fang, Sun Xuehua, Li Hongjie, Kong Xiaoni, Gao Yueqiu

Journal: Int J Biol Sci

PubMed ID: 35637971

Doi: 10.7150/ijbs.71431

Products & Services: Proteins, Expression, Isolation and Analysis

Comparison of pathogenicity of different subgenotype porcine reproductive and respiratory syndrome viruses isolated in China

Authors: Jie Zhang, Juan Bai, Yangyang Sun, Xing Liu, Yanni Gao, Xianwei Wang, Yuanqi Yang, Ping Jiang

Journal: Microb Pathog

PubMed ID: 35640766

Doi: 10.1016/j.micpath.2022.105607

Products & Services: DNA Sequencing

Complex protein interactions mediate Drosophila Lar function in muscle tissue

Authors: Jessica Kawakami, David Brooks, Rana Zalmai, Steven D Hartson, Samuel Bouyain, Erika R Geisbrecht

Journal: PLoS ONE

PubMed ID: 35622884

Doi: 10.1371/journal.pone.0269037

Products & Services: PCR Cloning and Subcloning

Sequestration of TDP-43 Aggregates by Cytoplasmic Expression of the proSAAS Chaperone

Authors: Juan R Peinado, Kriti Chaplot, Timothy S Jarvela, Edward M Barbieri, James Shorter, Iris Lindberg

Journal: ACS Chem Neurosci

PubMed ID: 35549000

Doi: 10.1021/acschemneuro.2c00156

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A myosin chaperone, UNC-45A, is a novel regulator of intestinal epithelial barrier integrity and repair

Authors: Susana Lechuga, Alexander X Cartagena-Rivera, Afshin Khan, Bert I Crawford, Vani Narayanan, Daniel E Conway, Jaakko Lehtimäki, Pekka Lappalainen, Florian Rieder, Michelle S Longworth, Andrei I Ivanov

Journal: FASEB J

PubMed ID: 35344227

Doi: 10.1096/fj.202200154R

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Humoral Immune Response Diversity to Different COVID-19 Vaccines: Implications for the "Green Pass" Policy

Authors: Immacolata Polvere, Alfredina Parrella, Lucrezia Zerillo, Serena Voccola, Gaetano Cardinale, Silvia D'Andrea, Jessica Raffaella Madera, Romania Stilo, Pasquale Vito, Tiziana Zotti

Journal: Front Immunol

PubMed ID: 35634315

Doi: 10.3389/fimmu.2022.833085

Oncogenic circTICRR suppresses autophagy via binding to HuR protein and stabilizing GLUD1 mRNA in cervical cancer

Authors: Tingjia Zhu, Yixuan Cen, Zhuoye Chen, Yanan Zhang, Lu Zhao, Jiaying Wang, Weiguo Lu, Xing Xie, Xinyu Wang

Journal: Cell Death Dis

PubMed ID: 35595754

Doi: 10.1038/s41419-022-04943-1

Products & Services: Proteins, Expression, Isolation and Analysis

Epitope-Based Vaccines against the Major Outer Membrane Protein Variable Domain 4 Elicit Protection in Mice

Authors: Amanda L Collar, Alexandria C Linville, Susan B Core, Kathryn M Frietze

Journal: Vaccines (Basel)

PubMed ID: 35746483

Doi: 10.3390/vaccines10060875

Products & Services: Proteins, Expression, Isolation and Analysis

Covalent Adduct Formation in Methylthio-d-ribose-1-phosphate Isomerase: Reaction Intermediate or Artifact?

Authors: Vamsee M Veeramachineni, Subashi T Ubayawardhana, Andrew S Murkin

Journal: Biochemistry

PubMed ID: 35580612

Doi: 10.1021/acs.biochem.2c00142

Products & Services: Plasmid DNA Preparation

CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids

Authors: Megan Lo, Amnon Sharir, Michael D Paul, Hayarpi Torosyan, Christopher Agnew, Amy Li, Cynthia Neben, Pauline Marangoni, Libin Xu, David R Raleigh, Natalia Jura, Ophir D Klein

Journal: Nat Commun

PubMed ID: 35504891

Doi: 10.1038/s41467-022-30186-x

Products & Services: Proteins, Expression, Isolation and Analysis

Coronavirus Disease 2019 Vaccine Booster Effects Are Seen in Human Milk Antibody Response

Authors: Jeffrey M Bender, Yesun Lee, Wesley A Cheng, Carolyn J Marentes Ruiz, Pia S Pannaraj

Journal: Front Nutr

PubMed ID: 35685893

Doi: 10.3389/fnut.2022.898849

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The key sulfometuron-methyl degrading bacteria isolation based on soil bacterial phylogenetic molecular ecological networks and application for bioremediation of contaminated soil by immobilization

Authors: Hao Zhang, Chun-Yang Liu, Xin Zhang, Hui-Ying Yang, Jie Sun, Cheng-Bin Liu, Na Li

Journal: Ecotoxicol Environ Saf

PubMed ID: 35561546

Doi: 10.1016/j.ecoenv.2022.113605

Products & Services: Proteins, Expression, Isolation and Analysis

Identification of RBMX as a splicing regulator in Parkinsonian mimetic induced alternative splicing of α-synuclein

Authors: Swaroop Thonda, Ravali L Vinnakota, Swathi V Kona, Shasi V Kalivendi

Journal: Biochim Biophys Acta Gene Regul Mech

PubMed ID: 35577270

Doi: 10.1016/j.bbagrm.2022.194825

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Enhancing fluxes through the mevalonate pathway in Saccharomyces cerevisiae by engineering the HMGR and β-alanine metabolism

Authors: Surui Lu, Chenyao Zhou, Xuena Guo, Zhengda Du, Yanfei Cheng, Zhaoyue Wang, Xiuping He

Journal: Microb Biotechnol

PubMed ID: 35531990

Doi: 10.1111/1751-7915.14072

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Smartly responsive DNA-miRNA hybrids packaged in exosomes for synergistic enhancement of cancer cell apoptosis

Authors: Fan Zhang, Albertina N Isak, Shiqi Yang, Yuchen Song, Lingjie Ren, Chang Feng, Guifang Chen

Journal: Nanoscale

PubMed ID: 35421879

Doi: 10.1039/d1nr08539e

Products & Services: Gene Synthesis

Glutathione S-transferase: a candidate gene for berry color in muscadine grapes (Vitis rotundifolia)

Authors: Aruna Varanasi, Margaret Worthington, Lacy Nelson, Autumn Brown, Thomas Mason Chizk, Renee Threlfall, Luke Howard, Patrick Conner, Rosa Figueroa-Balderas, Mélanie Massonnet, Dario Cantu, John R Clark

Journal: G3 (Bethesda)

PubMed ID: 35302606

Doi: 10.1093/g3journal/jkac060

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Crosstalk between IL-15Rα tumor-associated macrophages and breast cancer cells reduces CD8 T cell recruitment

Authors: Wenlong Zhang, Qing Zhang, Nanfei Yang, Qian Shi, Huifang Su, Tingsheng Lin, Zhonglei He, Wenxin Wang, Hongqian Guo, Pingping Shen

Journal: Cancer Commun (Lond)

PubMed ID: 35615815

Doi: 10.1002/cac2.12311

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A Novel Ig Domain-Containing C-Type Lectin Triggers the Intestine-Hemocyte Axis to Regulate Antibacterial Immunity in Crab

Authors: Kaimin Zhou, Yukai Qin, Yu Song, Ke Zhao, Weijuan Pan, Xingyu Nan, Yue Wang, Qun Wang, Weiwei Li

Journal: J Immunol

PubMed ID: 35508356

Doi: 10.4049/jimmunol.2101027

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Self-Assembling Nanovaccine Confers Complete Protection Against Zika Virus Without Causing Antibody-Dependent Enhancement

Authors: Heng Rong, Mi Qi, Jingdi Pan, Yuhan Sun, Jiawang Gao, Xiaowei Zhang, Wei Li, Bo Zhang, Xian-En Zhang, Zongqiang Cui

Journal: Front Immunol

PubMed ID: 35615356

Doi: 10.3389/fimmu.2022.905431

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Structural basis of sodium-dependent bile salt uptake into the liver

Authors: Kapil Goutam, Francesco S Ielasi, Els Pardon, Jan Steyaert, Nicolas Reyes

Journal: Nature

PubMed ID: 35545671

Doi: 10.1038/s41586-022-04723-z

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Duo Cadherin-Functionalized Microparticles Synergistically Induce Chondrogenesis and Cartilage Repair of Stem Cell Aggregates

Authors: Xueping Wang, Xingquan Xu, Yan Zhang, Xueying An, Xue Zhang, Guoqiang Chen, Qing Jiang, Jun Yang

Journal: Adv Healthc Mater

PubMed ID: 35485302

Doi: 10.1002/adhm.202200246

Products & Services: Mammalian Expression

Revisiting misfolding propensity of serum amyloid A1: Special focus on the signal peptide region

Authors: Morgan S Haines, Eduardo Ramirez, Kendall B E Moore, Jessica S Fortin

Journal: Biochem Biophys Rep

PubMed ID: 35664543

Doi: 10.1016/j.bbrep.2022.101284

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Antibodies targeting the European lobster (Palinurus elephas) vitellogenin developed by mRNA isolation and in-silico-designed antigenic peptides

Authors: Faustina B Cannea, Maria Cristina Follesa, Cristina Porcu, Rossano Rossino, Alessandra Olianas, Antonio Rescigno, Alessandra Padiglia

Journal: Biol Open

PubMed ID: 35452506

Doi: 10.1242/bio.059019

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Small, charged proteins in salmon louse (Lepeophtheirus salmonis) secretions modulate Atlantic salmon (Salmo salar) immune responses and coagulation

Authors: Aina-Cathrine Øvergård, Helena M D Midtbø, Lars A Hamre, Michael Dondrup, Gro E K Bjerga, Øivind Larsen, Jiwan Kumar Chettri, Kurt Buchmann, Frank Nilsen, Sindre Grotmol

Journal: Sci Rep

PubMed ID: 35568726

Doi: 10.1038/s41598-022-11773-w

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Functional validation of a novel AAAS variant in an atypical presentation of Allgrove syndrome

Authors: Erica L Macke, Joel A Morales-Rosado, Sarah K Macklin-Mantia, Christopher T Schmitz, Björn Oskarsson, Eric W Klee, Klaas J Wierenga

Journal: Mol Genet Genomic Med

PubMed ID: 35570467

Doi: 10.1002/mgg3.1966

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SARS-CoV-2 BA1 variant is neutralized by vaccine booster-elicited serum but evades most convalescent serum and therapeutic antibodies

Authors: Sabrina Lusvarghi, Simon D Pollett, Sabari Nath Neerukonda, Wei Wang, Richard Wang, Russell Vassell, Nusrat J Epsi, Anthony C Fries, Brian K Agan, David A Lindholm, Christopher J Colombo, Rupal Mody, Evan C Ewers, Tahaniyat Lalani, Anuradha Ganesan, Emilie Goguet, Monique Hollis-Perry, Si'Ana A Coggins, Mark P Simons, Leah C Katzelnick, Gregory Wang, David R Tribble, Lisa Bentley, Ann E Eakin, Christopher C Broder, Karl J Erlandson, Eric D Laing, Timothy H Burgess, Edward Mitre, Carol D Weiss

Journal: Sci Transl Med

PubMed ID: 35380448

Doi: 10.1126/scitranslmed.abn8543

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Lactoferrin Inhibition of the Complex Formation between ACE2 Receptor and SARS CoV-2 Recognition Binding Domain

Authors: Roberta Piacentini, Laura Centi, Mattia Miotto, Edoardo Milanetti, Lorenzo Di Rienzo, Martina Pitea, Paolo Piazza, Giancarlo Ruocco, Alberto Boffi, Giacomo Parisi

Journal: Int J Mol Sci

PubMed ID: 35628247

Doi: 10.3390/ijms23105436

Products & Services: Proteins, Expression, Isolation and Analysis

Computational approach for binding prediction of SARS-CoV-2 with neutralizing antibodies

Authors: Daria Beshnova, Yan Fang, Mingjian Du, Yehui Sun, Fenghe Du, Jianfeng Ye, Zhijian James Chen, Bo Li

Journal: Comput Struct Biotechnol J

PubMed ID: 35530743

Doi: 10.1016/j.csbj.2022.04.038

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α-toxin activates the NLRP3 inflammasome by engaging GPI-anchored proteins

Authors: Weidong Jing, Jordan Lo Pilato, Callum Kay, Shouya Feng, Daniel Enosi Tuipulotu, Anukriti Mathur, Cheng Shen, Chinh Ngo, Anyang Zhao, Lisa A Miosge, Sidra A Ali, Elizabeth E Gardiner, Milena M Awad, Dena Lyras, Avril A B Robertson, Nadeem O Kaakoush, Si Ming Man

Journal: Sci Immunol

PubMed ID: 35594341

Doi: 10.1126/sciimmunol.abm1803

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An Immunoinformatic Strategy to Develop New Multi-epitope Vaccine

Authors:

Journal: INT J PEPT RES THER

PubMed ID: 35573911

Doi: 10.1007/s10989-022-10406-0

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Constitutively Active STAT5b Feminizes Mouse Liver Gene Expression

Authors: Dana Lau-Corona, Hong Ma, Cameron Vergato, Andre Sarmento-Cabral, Mercedes Del Rio-Moreno, Rhonda D Kineman, David J Waxman

Journal: Endocrinology

PubMed ID: 35396838

Doi: 10.1210/endocr/bqac046

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Characterization of a New Multifunctional GH20 β--Acetylglucosaminidase From sp GC72 and Its Application in Converting Chitin Into Acetyl Glucosamine

Authors: Yan Chen, Ning Zhou, Xueman Chen, Guoguang Wei, Alei Zhang, Kequan Chen, Pingkai Ouyang

Journal: Front Microbiol

PubMed ID: 35620090

Doi: 10.3389/fmicb.2022.874908

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Lentiviral gene therapy prevents anti-human acid α-glucosidase antibody formation in murine Pompe disease

Authors: Qiushi Liang, Eva C Vlaar, Fabio Catalano, Joon M Pijnenburg, Merel Stok, Yvette van Helsdingen, Arnold G Vulto, Wendy W J Unger, Ans T van der Ploeg, W W M Pim Pijnappel, Niek P van Til

Journal: Mol Ther Methods Clin Dev

PubMed ID: 35662813

Doi: 10.1016/j.omtm.2022.04.016

Products & Services: Mammalian Expression

Biosynthesis of valerenic acid by engineered Saccharomyces cerevisiae

Authors: Mengya Zhao, Chuanbo Zhang, Haibin Wang, Shifan He, Wenyu Lu

Journal: Biotechnol Lett

PubMed ID: 35643816

Doi: 10.1007/s10529-022-03264-9

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A proof-of-concept study on the use of a fluorescein-based 18F-tracer for pretargeted PET

Authors: Hugo Helbert , Emily M Ploeg , Douwe F Samplonius , Simon N Blok , Ines F Antunes , Verena I Böhmer , Gert Luurtsema , Rudi A J O Dierckx , Ben L Feringa , Philip H Elsinga , Wiktor Szymanski , Wijnand Helfrich

Journal: EJNMMI Radiopharm Chem .

PubMed ID: 35239034

Doi: 10.1186/s41181-022-00155-2

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Cell-Penetrating Peptide TAT-HuR-HNS3 Suppresses Proinflammatory Gene Expression via Competitively Blocking Interaction of HuR with Its Partners

Authors: Ke Wang, Haibin Tong, Yitian Gao, Lan Xia, Xin Jin, Xiaoxue Li, Xianlu Zeng, Istvan Boldogh, Yueshuang Ke, Xueqing Ba

Journal: J Immunol

PubMed ID: 35444028

Doi: 10.4049/jimmunol.2200002

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Thioester-Assisted Sortase-A - Mediated Ligation

Authors: Chong Zuo 1, Ruichao Ding 1, Xiangwei Wu , Yuanxia Wang , Guo-Chao Chu, Lu-Jun Liang, Huasong Ai ， Ze-Bin Tong , Junxiong Mao , Qingyun Zheng , Tian Wang , Zichen Li , Lei Liu, Demeng Sun

Journal: Angew Chem Int Ed Engl

PubMed ID: 35514243

Doi: 10.1002/anie.202201887

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An Arabidopsis pre-RNA processing8a (prp8a) missense allele restores splicing of a subset of mis-spliced mRNAs

Authors: Roxanna J Llinas , Jia Qi Xiong , Natalie M Clark , Sarah E Burkhart , Bonnie Bartel

Journal: Plant Physiol

PubMed ID: 35608297

Doi: 10.1093/plphys/kiac221

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Adaptation-Proof SARS-CoV-2 Vaccine Design

Authors: Yashavantha L Vishweshwaraiah, Brianna Hnath, Brendan Rackley, Jian Wang, Abhinay Gontu, Morgan Chandler, Kirill A Afonin, Suresh V Kuchipudi, Neil Christensen, Neela H Yennawar, Nikolay V Dokholyan

Journal: biorxiv

PubMed ID: 35611332

Doi: doi.org/10.1002/adfm.202206055

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Effective-Component Compatibility of Bufei Yishen Formula III Combined with Electroacupuncture Suppresses Inflammatory Response in Rats with Chronic Obstructive Pulmonary Disease via Regulating SIRT1/NF-B Signaling

Authors: Fanli Jin, Lanxi Zhang, Kai Chen, Yufang Miao, Yang Liu, Yange Tian, Jiansheng Li

Journal: Biomed Res Int

PubMed ID: 35586807

Doi: 10.1155/2022/3360771

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3,5,3'-Triiodothyronine-Loaded Liposomes Inhibit Hepatocarcinogenesis Inflammation-Associated Macrophages

Authors: Gangqi Sun, Xiaojuan Hou, Luyao Zhang, Hengyan Zhang, Changchun Shao, Fengwei Li, Chen Zong, Rong Li, Junxia Shi, Xue Yang, Li Zhang

Journal: Front Oncol

PubMed ID: 35646705

Doi: 10.3389/fonc.2022.877982

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Identification and Functional Characterization of Peptides With Antimicrobial Activity From the Syphilis Spirochete,

Authors: Simon Houston, Ethan Schovanek, Kate M E Conway, Sarah Mustafa, Alloysius Gomez, Raghavendran Ramaswamy, Ayman Haimour, Martin J Boulanger, Lisa A Reynolds, Caroline E Cameron

Journal: Front Microbiol

PubMed ID: 35722306

Doi: 10.3389/fmicb.2022.888525

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Carboxymethylcellulose biofunctionalized ternary quantum dots for subcellular-targeted brain cancer nanotheranostics

Authors: Alexandra A P Mansur, Mayara R B Paiva, Oliver A L Cotta, Luciana M Silva, Isadora C Carvalho, Nádia S V Capanema, Sandhra M Carvalho, Érica A Costa, Nelson R Martin, Roselene Ecco, Beatriz S Santos, Silvia L Fialho, Zélia I P Lobato, Herman S Mansur

Journal: Int J Biol Macromol

PubMed ID: 35513094

Doi: 10.1016/j.ijbiomac.2022.04.207

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The Toxoplasma glucan phosphatase TgLaforin utilizes a distinct functional mechanism that can be exploited by therapeutic inhibitors

Authors: Robert D Murphy, Tiantian Chen, Jianping Lin, Rongjun He, Li Wu, Caden R Pearson, Savita Sharma, Carl D Vander Kooi, Anthony P Sinai, Zhong-Yin Zhang, Craig W Vander Kooi, Matthew S Gentry

Journal: J Biol Chem

PubMed ID: 35640720

Doi: 10.1016/j.jbc.2022.102089

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Phosphatidylinositol transfer protein/planar cell polarity axis regulates neocortical morphogenesis by supporting interkinetic nuclear migration

Authors: Zhigang Xie, Vytas A Bankaitis

Journal: Cell Rep

PubMed ID: 35649377

Doi: 10.1016/j.celrep.2022.110869

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Crosstalk of hepatocyte nuclear factor 4a and glucocorticoid receptor in the regulation of lipid metabolism in mice fed a high-fat-high-sugar diet

Authors: Hong Lu, Xiaohong Lei, Rebecca Winkler, Savio John, Devendra Kumar, Wenkuan Li, Yazen Alnouti

Journal: Lipids Health Dis

PubMed ID: 35614477

Doi: 10.1186/s12944-022-01654-6

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Antibody engineering improves neutralization activity against K417 spike mutant SARS-CoV-2 variants

Authors: Lili Li, Meiling Gao, Peng Jiao, Shulong Zu, Yong-Qiang Deng, Dingyi Wan, Yang Cao, Jing Duan, Saba R Aliyari, Jie Li, Yueyue Shi, Zihe Rao, Cheng-Feng Qin, Yu Guo, Genhong Cheng, Heng Yang

Journal: Cell Biosci

PubMed ID: 35581593

Doi: 10.1186/s13578-022-00794-7

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Identification, expression and subcellular localization of Orc1 in the microsporidian Nosema bombycis

Authors: Fuzhen Sun, Guanyu Zhu, Ping He, Erjun Wei, Runpeng Wang, Qiang Wang, Xudong Tang, Yiling Zhang, Zhongyuan Shen

Journal: Gene

PubMed ID: 35609797

Doi: 10.1016/j.gene.2022.146607

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Preclinical Studies of Granulysin-Based Anti-MUC1-Tn Immunotoxins as a New Antitumoral Treatment

Authors: Patricia Guerrero-Ochoa, Raquel Ibáñez-Pérez, Germán Berbegal-Pinilla, Diederich Aguilar, Isabel Marzo, Francisco Corzana, Martha Minjárez-Sáenz, Javier Macías-León, Blanca Conde, Javier Raso, Ramón Hurtado-Guerrero, Alberto Anel

Journal: Biomedicines

PubMed ID: 35740244

Doi: 10.3390/biomedicines10061223

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A minimal bile salt excretory pump promoter allows bile acid-driven physiological regulation of transgene expression from a gene therapy vector

Authors: Javier Martínez-García, Manuela Molina, Leticia Odriozola, Angie Molina, Gloria González-Aseguinolaza, Nicholas D Weber, Cristian Smerdou

Journal: Cell Biosci

PubMed ID: 35641984

Doi: 10.1186/s13578-022-00803-9

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Electrostatics Drive the Molecular Chaperone BiP to Preferentially Bind Oligomerized States of a Client Protein

Authors: Erin E Deans, Judy L M Kotler, Wei-Shao Wei, Timothy O Street

Journal: J Mol Biol

PubMed ID: 35597552

Doi: 10.1016/j.jmb.2022.167638

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Atypical B cells up-regulate costimulatory molecules during malaria and secrete antibodies with T follicular helper cell support

Authors: Christine S Hopp, Jeff Skinner, Sarah L Anzick, Christopher M Tipton, Mary E Peterson, Shanping Li, Safiatou Doumbo, Kassoum Kayentao, Aissata Ongoiba, Craig Martens, Boubacar Traore, Peter D Crompton

Journal: Sci Immunol

PubMed ID: 35559666

Doi: 10.1126/sciimmunol.abn1250

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Candidate Chemosensory Genes Identified in the Adult Antennae of and Binding Property of Odorant-Binding Protein 15

Authors: Xiao Li, Jian-Wen Li, Wen-Xiu Sun, Wei Li, Hua-Yuan Gao, Tong-Xian Liu, Ming-Jing Qu

Journal: Front Physiol

PubMed ID: 35711318

Doi: 10.3389/fphys.2022.907667

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Structural variation between neuropeptide isoforms affects function in the lobster cardiac system

Authors: Audrey J Muscato, Daniel J Powell, Warsameh Bulhan, Evalyn S Mackenzie, Alixander Pupo, Madeline Rolph, Andrew E Christie, Patsy S Dickinson

Journal: Gen Comp Endocrinol

PubMed ID: 35623446

Doi: 10.1016/j.ygcen.2022.114065

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Sox2 levels regulate the chromatin occupancy of WNT mediators in epiblast progenitors responsible for vertebrate body formation

Authors: Robert Blassberg, Harshil Patel, Thomas Watson, Mina Gouti, Vicki Metzis, M Joaquina Delás, James Briscoe

Journal: Nat Cell Biol

PubMed ID: 35550614

Doi: 10.1038/s41556-022-00910-2

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The CD8α hinge is intrinsically disordered with a dynamic exchange that includes proline cis-trans isomerization

Authors: Xiang Chen, Justin M Mirazee, Katarzyna A Skorupka, Hiroshi Matsuo, Philippe Youkharibache, Naomi Taylor, Kylie J Walters

Journal: J Magn Reson

PubMed ID: 35617919

Doi: 10.1016/j.jmr.2022.107234

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SOLVx therapeutics vaccine - Activate T-cell immunity using broad surveillance epitope strategy against mutant strains SARS-COV2

Authors: Md Shamsuddin Sultan Khan, John A Catanzaro

Journal: Biomed Pharmacother

PubMed ID: 35653885

Doi: 10.1016/j.biopha.2022.113212

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CBR3-AS1 Accelerates the Malignant Proliferation of Gestational Choriocarcinoma Cells by Stabilizing SETD4

Authors: Yajuan Zhang, Hongxiu Zhang, Xiaolei Zhang, Bin Liu

Journal: Dis Markers

PubMed ID: 35655916

Doi: 10.1155/2022/7155525

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IgG targeting distinct seasonal coronavirus- conserved SARS-CoV-2 spike subdomains correlates with differential COVID-19 disease outcomes

Authors: Jose L Garrido, Matías A Medina, Felipe Bravo, Sarah McGee, Francisco Fuentes-Villalobos, Mario Calvo, Yazmin Pinos, James W Bowman, Christopher D Bahl, Maria Ines Barria, Rebecca A Brachman, Raymond A Alvarez

Journal: Cell Rep

PubMed ID: 35617962

Doi: 10.1016/j.celrep.2022.110904

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Thymosin α-1 Reverses M2 Polarization of Tumor-Associated Macrophages during Efferocytosis

Authors: Yi-Ting Wei, Xu-Ru Wang, Chunguang Yan, Fang Huang, Yunpeng Zhang, Xueming Liu, Zhi-Fa Wen, Xiao-Tong Sun, Yue Zhang, Yong-Qiang Chen, Rong Gao, Ning Pan, Li-Xin Wang

Journal: Cancer Res

PubMed ID: 35364609

Doi: 10.1158/0008-5472.CAN-21-4260

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BCG-Based Vaccines Elicit Antigen-Specific Adaptive and Trained Immunity against SARS-CoV-2 and

Authors: Jorge A Soto, Fabián E Díaz, Angello Retamal-Díaz, Nicolás M S Gálvez, Felipe Melo-González, Alejandro Piña-Iturbe, Mario A Ramírez, Karen Bohmwald, Pablo A González, Susan M Bueno, Alexis M Kalergis

Journal: Vaccines (Basel)

PubMed ID: 35632475

Doi: 10.3390/vaccines10050721

Products & Services: Proteins, Expression, Isolation and Analysis

Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein

Authors: M Alejandra Tortorici, Alexandra C Walls, Anshu Joshi, Young-Jun Park, Rachel T Eguia, Marcos C Miranda, Elizabeth Kepl, Annie Dosey, Terry Stevens-Ayers, Michael J Boeckh, Amalio Telenti, Antonio Lanzavecchia, Neil P King, Davide Corti, Jesse D Bloom, David Veesler

Journal: Cell

PubMed ID: 35700730

Doi: 10.1016/j.cell.2022.05.019

Products & Services: Mammalian Expression

Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen

Authors: Zaid Taha, Rozanne Arulanandam, Glib Maznyi, Elena Godbout, Madalina E Carter-Timofte, Naziia Kurmasheva, Line S Reinert, Andrew Chen, Mathieu J F Crupi, Stephen Boulton, Geneviève Laroche, Alexandra Phan, Reza Rezaei, Nouf Alluqmani, Anna Jirovec, Alexandra Acal, Emily E F Brown, Ragunath Singaravelu, Julia Petryk, Manja Idorn, Kyle G Potts, Hayley Todesco, Cini John, Douglas J Mahoney, Carolina S Ilkow, Patrick Giguère, Tommy Alain, Marceline Côté, Søren R Paludan, David Olagnier, John C Bell, Taha Azad, Jean-Simon Diallo

Journal: Mol Ther

PubMed ID: 35526097

Doi: 10.1016/j.ymthe.2022.04.025

Products & Services: Mammalian Expression

BpEIN31 represses leaf senescence by inhibiting synthesis of ethylene and abscisic acid in Betula platyphylla

Authors: Shiyu Song, Mengyan Ge, Wei Wang, Chenrui Gu, Kun Chen, Qingzhu Zhang, Qibin Yu, Guifeng Liu, Jing Jiang

Journal: Plant Sci

PubMed ID: 35696929

Doi: 10.1016/j.plantsci.2022.111330

Products & Services: Protein Tools

Cancer genomic profiling identified dihydropyrimidine dehydrogenase deficiency in bladder cancer promotes sensitivity to gemcitabine

Authors: Shigehiro Tsukahara, Masaki Shiota, Dai Takamatsu, Shohei Nagakawa, Takashi Matsumoto, Ryo Kiyokoba, Mikako Yagi, Daiki Setoyama, Nozomi Noda, Shinya Matsumoto, Tetsutaro Hayashi, Alberto Contreras-Sanz, Peter C Black, Junichi Inokuchi, Kenichi Kohashi, Yoshinao Oda, Takeshi Uchiumi, Masatoshi Eto, Dongchon Kang

Journal: Sci Rep

PubMed ID: 35595780

Doi: 10.1038/s41598-022-12528-3

Products & Services: Mutagenesis Services

LncRNA JPX Promotes Esophageal Squamous Cell Carcinoma Progression by Targeting miR-516b-5p/VEGFA Axis

Authors: Yi He, Rong Hua, Yang Yang, Bin Li, Xufeng Guo, Zhigang Li

Journal: Cancers (Basel)

PubMed ID: 35681693

Doi: 10.3390/cancers14112713

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Analysis of rhodopsin G protein-coupled receptor orthologs reveals semiochemical peptides for parasite (Schistosoma mansoni) and host (Biomphalaria glabrata) interplay

Authors: Phong Phan, Di Liang, Min Zhao, Russell C Wyeth, Conor Fogarty, Mary G Duke, Donald P McManus, Tianfang Wang, Scott F Cummins

Journal: Sci Rep

PubMed ID: 35581232

Doi: 10.1038/s41598-022-11996-x

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Patients with treated indolent lymphomas immunized with BNT162b2 have reduced anti-spike neutralizing IgG to SARS-CoV-2 variants, but preserved antigen-specific T cell responses

Authors: Brendan Beaton, Sarah C Sasson, Katherine Rankin, Juliette Raedemaeker, Alexander Wong, Priyanka Hastak, Chansavath Phetsouphanh, Andrew Warden, Vera Klemm, C Mee Ling Munier, Alexandra Carey Hoppe, Fiona Tea, Aleha Pillay, Alberto Ospina Stella, Anupriya Aggarwal, Orly Lavee, Ian D Caterson, Stuart Turville, Anthony D Kelleher, Fabienne Brilot, Judith Trotman

Journal: Am J Hematol

PubMed ID: 35607995

Doi: 10.1002/ajh.26619

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Discovery and functional assessment of a novel adipocyte population driven by intracellular Wnt/β-catenin signaling in mammals

Authors: Zhi Liu, Tian Chen, Sicheng Zhang, Tianfang Yang, Yun Gong, Hong-Wen Deng, Ding Bai, Weidong Tian, YiPing Chen

Journal: Elife

PubMed ID: 35503096

Doi: 10.7554/eLife.77740

Products & Services: Molecular Biology Reagents

Mitochondrial and glucose metabolic dysfunctions in granulosa cells induce impaired oocytes of polycystic ovary syndrome through Sirtuin 3

Authors: Qing Zhang, Jun Ren, Fangfang Wang, Manman Pan, Long Cui, Mingqian Li, Fan Qu

Journal: Free Radic Biol Med

PubMed ID: 35594990

Doi: 10.1016/j.freeradbiomed.2022.05.010

Products & Services: Proteins, Expression, Isolation and Analysis

A Transfected Parasite Line Expressing eGFP Is Able to Complete the Full Life Cycle of the Parasite in Mammalian and Tick Hosts

Authors: Wendell C Johnson, Hala E Hussein, Janaina Capelli-Peixoto, Jacob M Laughery, Naomi S Taus, Carlos E Suarez, Massaro W Ueti

Journal: Pathogens

PubMed ID: 35745477

Doi: 10.3390/pathogens11060623

Products & Services: Plasmid DNA Preparation

Multiple stem-loop primers induced cascaded loop-mediated isothermal amplification for direct recognition and specific detection of circular RNAs

Authors: Xin Liu, Pengbo Zhang, Kejian Gao, Xiaoyu Wang, Zhengping Li

Journal: Analyst

PubMed ID: 35506753

Doi: 10.1039/d2an00261b

Products & Services: Proteins, Expression, Isolation and Analysis

An aggregation-induced emission immunoassay for broad detection of polychlorinated biphenyls in chicken and crab

Authors: Chang Han, Yulong Wang, Pengyan Liu, Pan Li, Beibei Liu, Ning Ding, Michael N Routledge, Zhengjiang Liu, Cunzheng Zhang

Journal: Anal Bioanal Chem

PubMed ID: 35606453

Doi: 10.1007/s00216-022-04123-2

Products & Services: Proteins, Expression, Isolation and Analysis

SERCA interacts with chitin synthase and participates in cuticular chitin biogenesis in Drosophila

Authors: Weixing Zhu, Yanwei Duan, Jiqiang Chen, Hans Merzendorfer, Xu Zou, Qing Yang

Journal: Insect Biochem Mol Biol

PubMed ID: 35525402

Doi: 10.1016/j.ibmb.2022.103783

Products & Services: Proteins, Expression, Isolation and Analysis

Are Hamsters a Suitable Model for Evaluating the Immunogenicity of RBD-Based Anti-COVID-19 Subunit Vaccines?

Authors: Iuliia A Merkuleva, Dmitry N Shcherbakov, Mariya B Borgoyakova, Anastasiya A Isaeva, Valentina S Nesmeyanova, Natalia V Volkova, Vazirbek S Aripov, Daniil V Shanshin, Larisa I Karpenko, Svetlana V Belenkaya, Elena I Kazachinskaia, Ekaterina A Volosnikova, Tatiana I Esina, Alexandr A Sergeev, Kseniia A Titova, Yulia V Konyakhina, Anna V Zaykovskaya, Oleg V Pyankov, Evgeniia A Kolosova, Olesya E Viktorina, Arseniya A Shelemba, Andrey P Rudometov, Alexander A Ilyichev

Journal: Viruses

PubMed ID: 35632800

Doi: 10.3390/v14051060

Products & Services: Mammalian Expression

Development of DNA Vaccine Candidate against SARS-CoV-2

Authors: Xingyun Wang, Nino Rcheulishvili, Jie Cai, Cong Liu, Fengfei Xie, Xing Hu, Nuo Yang, Mengqi Hou, Dimitri Papukashvili, Yunjiao He, Peng George Wang

Journal: Viruses

PubMed ID: 35632789

Doi: 10.3390/v14051049

Complementary Roles of Antibody Heavy and Light Chain Somatic Hypermutation in Conferring Breadth and Potency to the HIV-1-Specific CAP256-VRC26 bNAb Lineage

Authors: David Sacks, Kevin Wiehe, Lynn Morris, Penny L Moore

Journal: J Virol

PubMed ID: 35510865

Doi: 10.1128/jvi.00270-22

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OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage

Authors: Xiaoli S Wu, Xue-Yan He, Jonathan J Ipsaro, Yu-Han Huang, Jonathan B Preall, David Ng, Yan Ting Shue, Julien Sage, Mikala Egeblad, Leemor Joshua-Tor, Christopher R Vakoc

Journal: Nature

PubMed ID: 35576971

Doi: 10.1038/s41586-022-04842-7

Products & Services: ORF cDNA Clones/MolecularCloud

Characterization of the Biomass Degrading Enzyme GuxA from

Authors: Neal N Hengge, Sam J B Mallinson, Patthra Pason, Vladimir V Lunin, Markus Alahuhta, Daehwan Chung, Michael E Himmel, Janet Westpheling, Yannick J Bomble

Journal: Int J Mol Sci

PubMed ID: 35682749

Doi: 10.3390/ijms23116070

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Tuaimenal A, a Meroterpene from the Irish Deep-Sea Soft Coral , Displays Inhibition of the SARS-CoV-2 3CLpro Enzyme

Authors: Nicole E Avalon, Jordan Nafie, Carolina De Marco Verissimo, Luke C Warrensford, Sarah G Dietrick, Amanda R Pittman, Ryan M Young, Fiona L Kearns, Tracess Smalley, Jennifer M Binning, John P Dalton, Mark P Johnson, H Lee Woodcock, A Louise Allcock, Bill J Baker

Journal: J Nat Prod

PubMed ID: 35549259

Doi: 10.1021/acs.jnatprod.2c00054

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A paper-based optical sensor for the screening of viruses through the cysteine residues of their surface proteins: A proof of concept on the detection of coronavirus infection

Authors: Mahnaz D Gholami, Kristyan Guppy-Coles, Serena Nihal, Daman Langguth, Prashant Sonar, Godwin A Ayoko, Chamindie Punyadeera, Emad L Izake

Journal: Talanta

PubMed ID: 35660992

Doi: 10.1016/j.talanta.2022.123630

Products & Services: Recombinant Antibody Expression

Immunoinformatic approach for the construction of multi-epitopes vaccine against omicron COVID-19 variant

Authors: Kanwal Khan, Salman Ali Khan, Khurshid Jalal, Zaheer Ul-Haq, Reaz Uddin

Journal: Virology

PubMed ID: 35576833

Doi: 10.1016/j.virol.2022.05.001

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Efficacy, T cell activation and antibody responses in accelerated Plasmodium falciparum sporozoite chemoprophylaxis vaccine regimens

Authors: Javier Ibanez, Rolf Fendel, Freia-Raphaella Lorenz, Patricia Granados-Bayon, Sina Brückner, Meral Esen, Mihály Sulyok, Zita Sulyok, Steffen Borrmann, Petra Bacher, Alexander Scheffold, Stephen L Hoffman, Peter G Kremsner, Benjamin Mordmüller

Journal: npj Vaccines

PubMed ID: 35641527

Doi: 10.1038/s41541-022-00473-1

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Elimination of a closed population of the yellow fever mosquito, Aedes aegypti, through releases of self-limiting male mosquitoes

Authors: Prabhakargouda B Patil, Shaibal Kumar Dasgupta, Kevin Gorman, Angela Pickl-Herk, Mirel Puinean, Andrew McKemey, Bharat Char, Usha B Zehr, Shirish R Barwale

Journal: PLoS Negl Trop Dis

PubMed ID: 35576193

Doi: 10.1371/journal.pntd.0010315

Products & Services: Plasmid DNA Preparation

The Carotenoid Esterification Gene Controls Pale-Yellow Petal Color in Flowering Chinese Cabbage ( L subsp )

Authors: Peirong Li, Sirui Lv, Deshuang Zhang, Tongbing Su, Xiaoyun Xin, Weihong Wang, Xiuyun Zhao, Yangjun Yu, Yaowei Zhang, Shuancang Yu, Fenglan Zhang

Journal: Front Plant Sci

PubMed ID: 35592555

Doi: 10.3389/fpls.2022.844140

Products & Services: GenParts™ DNA Fragments

Novel small molecules targeting bZIP23 TF improve stomatal conductance and photosynthesis under mild drought stress by regulating ABA

Authors: Vanitha Pa, Preethi Vijayaraghavareddy, Akshay Uttarkar, Akashata Dawane, Sujitha D, Ashwin V, Babitha Kc, Vidya Niranjan, Sheshshayee Ms, Anuradha Cv, Udayakumar Makarla, Ramu S Vemanna

Journal: FEBS J

PubMed ID: 35445538

Doi: 10.1111/febs.16461

Products & Services: PCR Cloning and Subcloning

Mammalian Display Platform for the Maturation of Bispecific TCR-Based Molecules

Authors: Janine Dilchert, Martin Hofmann, Felix Unverdorben, Roland Kontermann, Sebastian Bunk

Journal: Antibodies (Basel)

PubMed ID: 35645207

Doi: 10.3390/antib11020034

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Randomizing of Oligopeptide Conformations by Nearest Neighbor Interactions between Amino Acid Residues

Authors: Reinhard Schweitzer-Stenner, Bridget Milorey, Harald Schwalbe

Journal: Biomolecules

PubMed ID: 35625612

Doi: 10.3390/biom12050684

Products & Services: Peptide Synthesis

Molecular mechanism of the wake-promoting agent TAK-925

Authors: Jie Yin, Yanyong Kang, Aaron P McGrath, Karen Chapman, Megan Sjodt, Eiji Kimura, Atsutoshi Okabe, Tatsuki Koike, Yuhei Miyanohana, Yuji Shimizu, Rameshu Rallabandi, Peng Lian, Xiaochen Bai, Mack Flinspach, Jef K De Brabander, Daniel M Rosenbaum

Journal: Nat Commun

PubMed ID: 35614071

Doi: 10.1038/s41467-022-30601-3

Products & Services: Proteins, Expression, Isolation and Analysis

Reduction of Influenza A Virus Transmission in Mice by a Universal Intranasal Vaccine Candidate is Long-Lasting and Does Not Require Antibodies

Authors: Graeme E Price, Chia-Yun Lo, Julia A Misplon, Suzanne L Epstein

Journal: J Virol

PubMed ID: 35638848

Doi: 10.1128/jvi.00320-22

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Allosteric Regulation of IGF2BP1 as a Novel Strategy for the Activation of Tumor Immune Microenvironment

Authors: Yang Liu, Qiang Guo, Heng Yang, Xiao-Wen Zhang, Na Feng, Jing-Kang Wang, Ting-Ting Liu, Ke-Wu Zeng, Peng-Fei Tu

Journal: ACS Cent Sci

PubMed ID: 36032766

Doi: 10.1021/acscentsci.2c00107

Products & Services: Plasmid DNA Preparation

Optimization of the antimicrobial peptide Bac7 by deep mutational scanning

Authors: Philipp Koch, Steven Schmitt, Alexander Heynisch, Anja Gumpinger, Irene Wüthrich, Marina Gysin, Dimitri Shcherbakov, Sven N Hobbie, Sven Panke, Martin Held

Journal: BMC Biol

PubMed ID: 35578204

Doi: 10.1186/s12915-022-01304-4

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Immunogenicity, safety, and antiphospholipid antibodies after SARS-CoV-2 vaccine in patients with primary antiphospholipid syndrome

Authors: Flavio Signorelli, Gustavo Guimarães Moreira Balbi, Nadia E Aikawa, Clovis A Silva, Léonard de Vinci Kanda Kupa, Ana C Medeiros-Ribeiro, Emily Fn Yuki, Sandra G Pasoto, Carla Gs Saad, Eduardo F Borba, Luciana Parente Costa Seguro, Tatiana Pedrosa, Vitor Antonio de Angeli Oliveira, Ana Luisa Cerqueira de Sant'Ana Costa, Carolina T Ribeiro, Roseli Eliana Beseggio Santos, Danieli Castro Oliveira Andrade, Eloisa Bonfá

Journal: Lupus

PubMed ID: 35593174

Doi: 10.1177/09612033221102073

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Luteolin suppresses TNF-α-induced inflammatory injury and senescence of nucleus pulposus cells via the Sirt6/NF-κB pathway

Authors: Tian Xie, Jun Yuan, Ling Mei, Ping Li, Ruijie Pan

Journal: Exp Ther Med

PubMed ID: 35747154

Doi: 10.3892/etm.2022.11396

Products & Services: Custom DNA/RNA Oligos

Performance analysis among multiple fully automated anti-SARS-CoV-2 antibody measurement reagents: A potential indicator for the correlation of protection in the antibody titer

Authors: Ryo Kobayashi, Ema Suzuki, Ryosei Murai, Makito Tanaka, Yoshihiro Fujiya, Satoshi Takahashi

Journal: J Infect Chemother

PubMed ID: 35667939

Doi: 10.1016/j.jiac.2022.05.016

Products & Services: Recombinant Proteins

Phosphorylation of HORMA-domain protein HTP-3 at Serine 285 is dispensable for crossover formation

Authors: Debabrata Das, Shalini Trivedi, Jitka Blazícková, Swathi Arur, Nicola Silva

Journal: G3 (Bethesda)

PubMed ID: 35389463

Doi: 10.1093/g3journal/jkac079

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Assessing the Activity of Antimicrobial Peptides Against Common Marine Bacteria Located in Rotifer (Brachionus plicatilis) Cultures

Authors: Chelsea Woods, Lindsey Woolley, Gavin Partridge, Mengqi Chen, Evan F Haney, Robert E W Hancock, Nicky Buller, Andrew Currie

Journal: Probiotics Antimicrob Proteins

PubMed ID: 35612776

Doi: 10.1007/s12602-022-09928-2

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