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Structures of topoisomerase V in complex with DNA reveal unusual DNA-binding mode and novel relaxation mechanism

Authors: Amy Osterman, Alfonso Mondragón

Journal: Elife

PubMed ID: 35969036

Doi: 10.7554/eLife.72702

Products & Services: Plasmid DNA Preparation

Salvianolic acid B activates chondrocytes autophagy and reduces chondrocyte apoptosis in obese mice via the KCNQ1OT1/miR-128-3p/SIRT1 signaling pathways

Authors: Tianwen Sun, Fei Wang, Gaojian Hu, Zhizhou Li

Journal: Nutr Metab (Lond)

PubMed ID: 35922815

Doi: 10.1186/s12986-022-00686-0

Products & Services: Gene Synthesis

High-titre production of aromatic amines in metabolically engineered Escherichia coli

Authors: Taiwei Yang, Peiling Wu, Yang Zhang, Mingfeng Cao, Jifeng Yuan

Journal: J Appl Microbiol

PubMed ID: 35938518

Doi: 10.1111/jam.15745

Products & Services: Codon Optimization

MTP18 inhibition triggers mitochondrial hyperfusion to induce apoptosis through ROS-mediated lysosomal membrane permeabilization-dependent pathway in oral cancer

Authors: Debasna Pritimanjari Panigrahi, Srimanta Patra, Bishnu Prasad Behera, Pradyota Kumar Behera, Shankargouda Patil, Birija Sankar Patro, Laxmidhar Rout, Itisam Sarangi, Sujit Kumar Bhutia

Journal: Free Radic Biol Med

PubMed ID: 35985563

Doi: 10.1016/j.freeradbiomed.2022.08.019

Products & Services: Custom Vector Construction

A Rapid Translational Immune Response Program in CD8 Memory T Lymphocytes

Authors: Darin Salloum, Kamini Singh, Natalie R Davidson, Linlin Cao, David Kuo, Viraj R Sanghvi, Man Jiang, Maria Tello Lafoz, Agnes Viale, Gunnar Ratsch, Hans-Guido Wendel

Journal: J Immunol

PubMed ID: 36002234

Doi: 10.4049/jimmunol.2100537

Products & Services: Catalog Peptides

Effects of boosted mRNA and adenoviral-vectored vaccines on immune responses to omicron BA1 and BA2 following the heterologous CoronaVac/AZD1222 vaccination

Authors: Nungruthai Suntronwong, Sitthichai Kanokudom, Chompoonut Auphimai, Suvichada Assawakosri, Thanunrat Thongmee, Preeyaporn Vichaiwattana, Thaneeya Duangchinda, Warangkana Chantima, Pattarakul Pakchotanon, Jira Chansaenroj, Jiratchaya Puenpa, Pornjarim Nilyanimit, Donchida Srimuan, Thaksaporn Thatsanatorn, Natthinee Sudhinaraset, Nasamon Wanlapakorn, Juthathip Mongkolsapaya, Yong Poovorawan

Journal: J Med Virol

PubMed ID: 35924475

Doi: 10.1002/jmv.28044

Products & Services: Protein and Antibody Isolation

Translational potential of base-editing tools for gene therapy of monogenic diseases

Authors: Vasiliy V Reshetnikov, Angelina V Chirinskaite, Julia V Sopova, Roman A Ivanov, Elena I Leonova

Journal: Front Bioeng Biotechnol

PubMed ID: 36032737

Doi: 10.3389/fbioe.2022.942440

Products & Services: Codon Optimization

Signal Peptide-rheostat Dynamics Delay Secretory Preprotein Folding

Authors: Dries Smets, Jochem Smit, Ying Xu, Spyridoula Karamanou, Anastassios Economou

Journal: J Mol Biol

PubMed ID: 35970402

Doi: 10.1016/j.jmb.2022.167790

Products & Services: Custom Vector Construction

Generation of T-cell-receptor-negative CD8αβ-positive CAR T cells from T-cell-derived induced pluripotent stem cells

Authors: Sjoukje J C van der Stegen, Pieter L Lindenbergh, Roseanna M Petrovic, Hongyao Xie, Mame P Diop, Vera Alexeeva, Yuzhe Shi, Jorge Mansilla-Soto, Mohamad Hamieh, Justin Eyquem, Annalisa Cabriolu, Xiuyan Wang, Ramzey Abujarour, Tom Lee, Raedun Clarke, Bahram Valamehr, Maria Themeli, Isabelle Riviere, Michel Sadelain

Journal: Nat Biomed Eng

PubMed ID: 35941192

Doi: 10.1038/s41551-022-00915-0

Products & Services: PCR Cloning and Subcloning

Quorum Sensing Regulation of a Major Facilitator Superfamily Transporter Affects Multiple Streptococcal Virulence Factors

Authors: Jennifer C Chang, Reid V Wilkening, Kate M Rahbari, Michael J Federle

Journal: J Bacteriol

PubMed ID: 35938850

Doi: 10.1128/jb.00176-22

Products & Services: Catalog Peptides