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Antigen-Induced IL-1RA Production Discriminates Active and Latent Tuberculosis Infection

Authors: Cesar Sanchez, Luis Jaramillo-Valverde, Silvia Capristano, Gilmer Solis, Alonso Soto, Julio Valdivia-Silva, Julio A Poterico, Heinner Guio

Journal: Microorganisms

PubMed ID: 37374887

Doi: 10.3390/microorganisms11061385

Products & Services: Peptide Synthesis

Small heterodimer partner interacting leucine zipper protein (SMILE) ameliorates autoimmune arthritis via AMPK signaling pathway and the regulation of B cell activation

Authors: JooYeon Jhun, Jeonghyeon Moon, Ji Ye Kwon, Keun-Hyung Cho, Seang Yoon Lee, Hyun Sik Na, Mi-La Cho, Jun-Ki Min

Journal: Cell Commun Signal

PubMed ID: 37143079

Doi: 10.1186/s12964-023-01054-y

Products & Services: Codon Optimization

Topically Administered NOX4 Inhibitor, GLX7013114, Is Efficacious in Treating the Early Pathological Events of Diabetic Retinopathy

Authors: Stavroula Dionysopoulou, Per Wikstrom, Claudio Bucolo, Giovanni Luca Romano, Vincenzo Micale, Richard Svensson, Dimitris Spyridakos, Niki Mastrodimou, Spiros Georgakis, Panayotis Verginis, Erik Walum, Kyriaki Thermos

Journal: Diabetes

PubMed ID: 36821829

Doi: 10.2337/db22-0515

Products & Services: Protein and Antibody Isolation

The Nucleocapsid Proteins of SARS-CoV-2 and Its Close Relative Bat Coronavirus RaTG13 Are Capable of Inhibiting PKR- and RNase L-Mediated Antiviral Pathways

Authors: Kyle LeBlanc, Jessie Lynch, Christine Layne, Robert Vendramelli, Angela Sloan, Nikesh Tailor, Yvon Deschambault, Fushun Zhang, Darwyn Kobasa, David Safronetz, Yan Xiang, Jingxin Cao

Journal: Microbiol Spectr

PubMed ID: 37154717

Doi: 10.1128/spectrum.00994-23

Products & Services: Protein and Antibody Isolation

Functionalized Metal–Organic Framework-Modified Hydrogel That Breaks the Vicious Cycle of Inflammation and ROS for Repairing of Diabetic Bone Defects

Authors: An Lao, Jiaqing Wu, Dejian Li, Aili Shen, Yaxin Li, Yu Zhuang, Kaili Lin, Jianyong Wu, Jiaqiang Liu

Journal: Small

PubMed ID: 37183293

Doi: smll.202206919

Products & Services: Protein and Antibody Isolation

Co-delivery of Cas9 mRNA and guide RNAs edits hepatitis B virus episomal and integration DNA in mouse and tree shrew models

Authors: Junzhu Yi, Xinlin Lei, Fangteng Guo, Qiubing Chen, Xueyong Chen, Kaitao Zhao, Chengliang Zhu, Xiaoming Cheng, Jiangwei Lin, Hao Yin, Yuchen Xia

Journal: Antiviral research

PubMed ID: 37142191

Doi: 10.1016/j.antiviral.2023.105618

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

Immunogenic SARS-CoV-2 S and N Protein Peptide and Cytokine Combinations as Biomarkers for Early Prediction of Fatal COVID-19

Authors: Ekaterina Martynova , Shaimaa Hamza , Maria Markelova , Ekaterina Garanina , Yuriy Davidyuk , Venera Shakirova , Neha Kaushal , Manoj Baranwal , Robert J Stott-Marshall , Toshana L Foster , Albert Rizvanov , Svetlana Khaiboullina

Journal: Front Immunol .

PubMed ID: 35386707

Doi: 10.3389/fimmu.2022.830715

Products & Services: Peptide Synthesis

In vitro reconstitution of SARS-CoV-2 Nsp1-induced mRNA cleavage reveals the key roles of the N-terminal domain of Nsp1 and the RRM domain of eIF3g

Authors: Irina S. Abaeva, Yani Arhab, Anna Miscicka, Christopher U.T. Hellen, and Tatyana V. Pestova

Journal: bioRxiv .

PubMed ID: 37292671

Doi: 10.1101/gad.350829.123

Products & Services: Gene Synthesis

Simultaneous enhancement of multiple functional properties using evolution-informed protein design

Authors: Benjamin Fram, Ian Truebridge, Yang Su, Adam J Riesselman, John B Ingraham, Alessandro Passera, Eve Napier, Nicole N Thadani, Samuel Lim, Kristen Roberts, Gurleen Kaur, Michael Stiffler, Debora S Marks, Christopher D Bahl, Amir R Khan, Chris Sander, Nicholas P Gauthier

Journal: biorxiv

PubMed ID: 37214973

Doi: 10.1101/2023.05.09.539914

Products & Services: Molecular Biology Reagents

Inflammation Modifies miR-21 Expression Within Neuronal Extracellular Vesicles to Regulate Remyelination Following Spinal Cord Injury

Authors: Tianyu Han, Peiwen Song, Zuomeng Wu, Yunlei Liu, Wang Ying, Cailiang Shen

Journal: Stem Cell Rev Rep

PubMed ID: 37256514

Doi: 10.1007/s12015-023-10560-y

Products & Services: Gene Synthesis