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Engineering an adenine base editor in human embryonic stem cells with minimal DNA and RNA off-target activities

Authors: Zhenwu Zhang, Wanyu Tao, Shisheng Huang, Wenjun Sun, Yue Wang, Wen Jiang, Xingxu Huang, Chao-Po Lin

Journal: Mol Ther Nucleic Acids

PubMed ID: 35991312

Doi: 10.1016/j.omtn.2022.07.026

Products & Services: Gene Fragments

Immunogenicity and Protective Efficacy of a Recombinant Pichinde Viral-Vectored Vaccine Expressing Influenza Virus Hemagglutinin Antigen in Pigs

Authors: Sushmita Kumari, Jayeshbhai Chaudhari, Qinfeng Huang, Phillip Gauger, Marcelo Nunes De Almeida, Yuying Liang, Hinh Ly, Hiep L X Vu

Journal: Vaccines (Basel)

PubMed ID: 36146478

Doi: 10.3390/vaccines10091400

Products & Services: Gene Synthesis

Membrane transporters control cerebrospinal fluid formation independently of conventional osmosis to modulate intracranial pressure

Authors: Eva K Oernbo, Annette B Steffensen, Pooya Razzaghi Khamesi, Trine L Toft-Bertelsen, Dagne Barbuskaite, Frederik Vilhardt, Niklas J Gerkau, Katerina Tritsaris, Anja H Simonsen, Sara D Lolansen, Søren N Andreassen, Steen G Hasselbalch, Thomas Zeuthen, Christine R Rose, Vartan Kurtcuoglu, Nanna MacAulay

Journal: Fluids Barriers CNS

PubMed ID: 36038945

Doi: 10.1186/s12987-022-00358-4

Products & Services: Gene Synthesis

MTP18 inhibition triggers mitochondrial hyperfusion to induce apoptosis through ROS-mediated lysosomal membrane permeabilization-dependent pathway in oral cancer

Authors: Debasna Pritimanjari Panigrahi, Srimanta Patra, Bishnu Prasad Behera, Pradyota Kumar Behera, Shankargouda Patil, Birija Sankar Patro, Laxmidhar Rout, Itisam Sarangi, Sujit Kumar Bhutia

Journal: Free Radic Biol Med

PubMed ID: 35985563

Doi: 10.1016/j.freeradbiomed.2022.08.019

Products & Services: Custom Vector Construction

A Rapid Translational Immune Response Program in CD8 Memory T Lymphocytes

Authors: Darin Salloum, Kamini Singh, Natalie R Davidson, Linlin Cao, David Kuo, Viraj R Sanghvi, Man Jiang, Maria Tello Lafoz, Agnes Viale, Gunnar Ratsch, Hans-Guido Wendel

Journal: J Immunol

PubMed ID: 36002234

Doi: 10.4049/jimmunol.2100537

Products & Services: Catalog Peptides

Effects of boosted mRNA and adenoviral-vectored vaccines on immune responses to omicron BA1 and BA2 following the heterologous CoronaVac/AZD1222 vaccination

Authors: Nungruthai Suntronwong, Sitthichai Kanokudom, Chompoonut Auphimai, Suvichada Assawakosri, Thanunrat Thongmee, Preeyaporn Vichaiwattana, Thaneeya Duangchinda, Warangkana Chantima, Pattarakul Pakchotanon, Jira Chansaenroj, Jiratchaya Puenpa, Pornjarim Nilyanimit, Donchida Srimuan, Thaksaporn Thatsanatorn, Natthinee Sudhinaraset, Nasamon Wanlapakorn, Juthathip Mongkolsapaya, Yong Poovorawan

Journal: J Med Virol

PubMed ID: 35924475

Doi: 10.1002/jmv.28044

Products & Services: Protein and Antibody Isolation

The antibody landscapes following AS03 and MF59 adjuvanted H5N1 vaccination

Authors: Johannes B Goll, Aarti Jain, Travis L Jensen, Rafael Assis, Rie Nakajima, Algis Jasinskas, Lynda Coughlan, Sami R Cherikh, Casey E Gelber, S Khan, D Huw Davies, Philip Meade, Daniel Stadlbauer, Shirin Strohmeier, Florian Krammer, Wilbur H Chen, Philip L Felgner

Journal: npj Vaccines

PubMed ID: 36042229

Doi: 10.1038/s41541-022-00524-7

Products & Services: Protein and Antibody Isolation

A cytoskeletal vortex drives phage nucleus rotation during jumbo phage replication in E coli

Authors: Erica A Birkholz, Thomas G Laughlin, Emily Armbruster, Sergey Suslov, Jina Lee, Johannes Wittmann, Kevin D Corbett, Elizabeth Villa, Joe Pogliano

Journal: Cell Rep

PubMed ID: 35977483

Doi: 10.1016/j.celrep.2022.111179

Products & Services: Plasmid DNA Preparation

Structural basis for Sarbecovirus ORF6 mediated blockage of nucleocytoplasmic transport

Authors: Xiaopan Gao, Huabin Tian, Kaixiang Zhu, Qing Li, Wei Hao, Linyue Wang, Bo Qin, Hongyu Deng, Sheng Cui

Journal: Nat Commun

PubMed ID: 35970938

Doi: 10.1038/s41467-022-32489-5

Products & Services: Protein and Antibody Isolation

EmCyclinD-EmCDK4/6 complex is involved in the host EGF-mediated proliferation of germinative cells the EGFR-ERK pathway

Authors: Chonglv Feng, Zhe Cheng, Zhijian Xu, Ye Tian, Huimin Tian, Fan Liu, Damin Luo, Yanhai Wang